FERMA549029

CHRM2 Monoclonal Antibody (B8E5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA549029-Each-of-1 In Stock ₹ 54,073.92

FERMA549029 - Each of 1

₹ 54,073.92

In Stock

Quantity

1

Base Price: ₹ 54,073.92

GST (18%): ₹ 9,733.306

Total Price: ₹ 63,807.226

Antigen

CHRM2

Classification

Monoclonal

Concentration

100 μg/mL

Formulation

PBS with 0.1% BSA and no preservative

Gene Accession No.

P08172

Gene Symbols

CHRM2

Immunogen

Peptide VRTVEDGECYIQFFSNAAVTFGTAI(C): Human second extracellular loop residues 168-192

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Inhibition Assays, Western Blot

Clone

B8E5

Conjugate

Unconjugated

Gene

CHRM2

Gene Alias

7TM receptor; acetylcholine receptor; acetylcholine receptor, muscarinic 2; AChR M2; AChR-M2; Acm2; cardiac muscarinic acetylcholine receptor; cholinergic receptor; cholinergic receptor muscarinic 2; cholinergic receptor, muscarinic 2; cholinergic receptor, muscarinic 2, cardiac; cholinergic receptor, muscarinic 2, isoform a; Chrm2; Chrm-2; FLJ43243; HM2; M2; M2 muscarinic acetylcholine receptor; m2AChR; M2-mAChR; MGC120006; MGC120007; muscarinic acetylcholine receptor 2; muscarinic acetylcholine receptor m2; muscarinic M2 receptor; muscarinic receptor m2; unnamed protein product

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

1129

Content And Storage

4° C

Isotype

IgG2a

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Description

  • Monoclonal antibody B8E5 acts by functional dimerization of the receptor resulting in stabilization of the constitutive active receptor dimers and paradoxically induces a small decrease in carbachol affinity for the M2 receptor
  • It recognizes the pentapeptide VRTVE (aa 168-172) corresponding to the N-terminal part of the second extracellular loop of the human M2 receptor
  • Muscarinic cholinergic receptor 2 (CHRM2) is an Acetylcholine Receptor has been suggested to function as a presynaptic autoreceptor that inhibits acetylcholine release
  • The M2 receptor has also been suggested to mediate smooth muscle contractility
  • Alzheimer's disease (AD) involves selective loss of M2 subtype receptors in cortical and hippocampal regions of the human brain
  • Increase in M2 receptor heterozygosity has been associated with depression in women
  • The M2 receptor has been reported to be expressed in various regions of the brain including the cerebellum, cerebral cortex, hippocampus, medulla, striatum, and thalamus, and in lung and prostate.

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Show Difference

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FERMA549029

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Antigen:
CHRM2

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and no preservative

Gene Accession No.:
P08172

Gene Symbols:
CHRM2

Immunogen:
Peptide VRTVEDGECYIQFFSNAAVTFGTAI(C): Human second extracellular loop residues 168-192

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Functional Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Inhibition Assays, Western Blot

Clone:
B8E5

Conjugate:
Unconjugated

Gene:
CHRM2

Gene Alias:
7TM receptor; acetylcholine receptor; acetylcholine receptor, muscarinic 2; AChR M2; AChR-M2; Acm2; cardiac muscarinic acetylcholine receptor; cholinergic receptor; cholinergic receptor muscarinic 2; cholinergic receptor, muscarinic 2; cholinergic receptor, muscarinic 2, cardiac; cholinergic receptor, muscarinic 2, isoform a; Chrm2; Chrm-2; FLJ43243; HM2; M2; M2 muscarinic acetylcholine receptor; m2AChR; M2-mAChR; MGC120006; MGC120007; muscarinic acetylcholine receptor 2; muscarinic acetylcholine receptor m2; muscarinic M2 receptor; muscarinic receptor m2; unnamed protein product

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
1129

Content And Storage:
4° C

Isotype:
IgG2a

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FERMA549030

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Antigen:
Creatine Kinase BB

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P12277

Gene Symbols:
CKB

Immunogen:
Synthetic 17-mer peptide corresponding to the N-terminal sequence of human creatine kinase brain-type (SNSHNALKLRFPAEDEF) Aliases Creatine kinase B chain, B-CK

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
CK-BYK/21E10

Conjugate:
Biotin

Gene:
CKB

Gene Alias:
Bck; B-CK; brain creatine kinase; Ck3; Ck-3; CKB; Ckbb; Ckbr; CPK-B; creatine kinase B; creatine kinase B chain; creatine kinase brain; creatine kinase brain-type; Creatine kinase B-type; creatine kinase, brain; creatine kinase-B; Creatine phosphokinase B-type; Creatine phosphokinase M-type; epididymis luminal protein 211; epididymis secretory protein Li 29; HEL-211; HEL-S-29

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
1152

Content And Storage:
4° C

Isotype:
IgG2b

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FERMA549031

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Antigen:
COLEC10

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
Q9Y6Z7

Gene Symbols:
COLEC10

Immunogen:
Antibody 4F9D7 recognizes human Collectin-10 (CL-L1)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Inhibition Assays, Western Blot

Clone:
4F9D7

Conjugate:
Unconjugated

Gene:
COLEC10

Gene Alias:
CL-34; CLL1; CL-L1; Colec10; collectin liver 1; collectin liver protein 1; collectin subfamily member 10; collectin sub-family member 10; collectin sub-family member 10 (C-type lectin); collectin-10; Collectin-34; collectin-L1; UNQ366/PRO702

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
10584

Content And Storage:
4° C

Isotype:
IgG1

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FERMA549032

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Antigen:
CD21/CD35

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P19070

Gene Symbols:
Cr2

Immunogen:
Purified mouse CR1 from serum

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
7E9

Conjugate:
Unconjugated

Gene:
Cr2

Gene Alias:
C3b/C4b receptor; C3-binding protein; C3DR; CD21; CD35; CD35 antigen; Complement C3d receptor; complement component (3d/Epstein Barr virus) receptor 2; complement component 3d receptor 2; complement receptor 2; complement receptor type 1; complement receptor type 2; CR; Cr1; Cr-1; Cr2; Cr-2; CVID7; EBV receptor; Epstein-Barr virus receptor; expressed in B lymphocytes; SLEB9

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
12902

Content And Storage:
4° C

Isotype:
IgG2a