FERMA549051

IGF1R (CD221) Monoclonal Antibody (1B1), Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 FERMA549051-Each-of-1 In Stock ₹ 54,073.92

FERMA549051 - Each of 1

₹ 54,073.92

In Stock

Quantity

1

Base Price: ₹ 54,073.92

GST (18%): ₹ 9,733.306

Total Price: ₹ 63,807.226

Antigen

IGF1R (CD221)

Classification

Monoclonal

Concentration

100 μg/mL

Formulation

PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.

P08069

Gene Symbols

IGF1R

Immunogen

Recombinant IGF-1R (aa 1-932)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Inhibition Assays

Clone

1B1

Conjugate

Unconjugated

Gene

IGF1R

Gene Alias

A330103N21Rik; CD221; CD221 antigen; D930020L01; hyft; IGF 1 receptor; IGF 1R; IGF1R; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2

Host Species

Rat

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

3480

Content And Storage

4° C

Isotype

IgG2b

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Description

  • Antibody 1B1 recognizes the extracellular domain if IGF-1R
  • IGF1R, also known as Insulin-like Growth Factor 1 (IGF-1) Receptor, is a receptor tyrosine kinase activated by IGF-1 and IGF-2
  • IGFR has been implicated in a variety of cancers
  • The protein is a tetramer consisting of two alpha, and two beta subunits
  • The alpha-subunits binds to insulin growth factor 1 with higher affinity than to insulin growth factor 2
  • Binding results in a conformational change, followed by autophosphorylation of IGF-1R at positions 1134, 1135, 1136
  • The activated IGF-1R in turn, causes phosphorylation of substrate proteins, followed by sequential activation of RAS, RAF, and mitogen-activated protein kinase isoforms ERK, p38, and JNK, leading to the transcription of genes that drive proliferation.

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Img

Thermo Scientific

FERMA549051

--


Antigen:
IGF1R (CD221)

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P08069

Gene Symbols:
IGF1R

Immunogen:
Recombinant IGF-1R (aa 1-932)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Inhibition Assays

Clone:
1B1

Conjugate:
Unconjugated

Gene:
IGF1R

Gene Alias:
A330103N21Rik; CD221; CD221 antigen; D930020L01; hyft; IGF 1 receptor; IGF 1R; IGF1R; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3480

Content And Storage:
4° C

Isotype:
IgG2b

Img

Thermo Scientific

FERMA549052

--


Antigen:
IL1R1

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P13504

Gene Symbols:
Il1r1

Immunogen:
The monoclonal antibody binds to soluble mouse interleukin-1 receptor type I

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Western Blot

Clone:
D14e3

Conjugate:
Unconjugated

Gene:
Il1r1

Gene Alias:
antigen CD121a; CD121 alpha; CD121 antigen-like family member A; CD121a; CD121b; D2S1473; il1 receptor; il-1 receptor; IL-1 receptor alpha chain; IL1R; il-1r; IL1R1; IL-1R1; IL-1R-1; Il1r-1; IL1RA; IL-1R-alpha; IL1RT1; IL-1RT1; IL-1RT-1; IL-iR; interleukin 1 beta receptor type 1 short transmembrane form; interleukin 1 beta receptor type 1 soluble form; interleukin 1 bete receptor type 1 long transmembrane form; interleukin 1 receptor alpha, type I; interleukin 1 receptor type 1; interleukin 1 receptor, type I; interleukin-1 receptor; interleukin-1 receptor alpha; Interleukin-1 receptor type 1; Interleukin-1 receptor type 1, membrane form; Interleukin-1 receptor type 1, soluble form; Interleukin-1 receptor type I; mIL-1R1; p80; sIL-1R1

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16177

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

FERMA549053

--


Antigen:
IL1R1

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P13504

Gene Symbols:
Il1r1

Immunogen:
The monoclonal antibody binds to soluble mouse interleukin-1 receptor type I

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Functional Assay, Western Blot

Clone:
D1f3

Conjugate:
Unconjugated

Gene:
Il1r1

Gene Alias:
antigen CD121a; CD121 alpha; CD121 antigen-like family member A; CD121a; CD121b; D2S1473; il1 receptor; il-1 receptor; IL-1 receptor alpha chain; IL1R; il-1r; IL1R1; IL-1R1; IL-1R-1; Il1r-1; IL1RA; IL-1R-alpha; IL1RT1; IL-1RT1; IL-1RT-1; IL-iR; interleukin 1 beta receptor type 1 short transmembrane form; interleukin 1 beta receptor type 1 soluble form; interleukin 1 bete receptor type 1 long transmembrane form; interleukin 1 receptor alpha, type I; interleukin 1 receptor type 1; interleukin 1 receptor, type I; interleukin-1 receptor; interleukin-1 receptor alpha; Interleukin-1 receptor type 1; Interleukin-1 receptor type 1, membrane form; Interleukin-1 receptor type 1, soluble form; Interleukin-1 receptor type I; mIL-1R1; p80; sIL-1R1

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16177

Content And Storage:
4° C

Isotype:
IgG1

Img

Thermo Scientific

FERMA549054

--


Antigen:
IL1R1

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P13504

Gene Symbols:
Il1r1

Immunogen:
The monoclonal antibody binds to soluble mouse interleukin-1 receptor type I

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Immunoprecipitation, Inhibition Assays, Western Blot

Clone:
Reg20

Conjugate:
Unconjugated

Gene:
Il1r1

Gene Alias:
antigen CD121a; CD121 alpha; CD121 antigen-like family member A; CD121a; CD121b; D2S1473; il1 receptor; il-1 receptor; IL-1 receptor alpha chain; IL1R; il-1r; IL1R1; IL-1R1; IL-1R-1; Il1r-1; IL1RA; IL-1R-alpha; IL1RT1; IL-1RT1; IL-1RT-1; IL-iR; interleukin 1 beta receptor type 1 short transmembrane form; interleukin 1 beta receptor type 1 soluble form; interleukin 1 bete receptor type 1 long transmembrane form; interleukin 1 receptor alpha, type I; interleukin 1 receptor type 1; interleukin 1 receptor, type I; interleukin-1 receptor; interleukin-1 receptor alpha; Interleukin-1 receptor type 1; Interleukin-1 receptor type 1, membrane form; Interleukin-1 receptor type 1, soluble form; Interleukin-1 receptor type I; mIL-1R1; p80; sIL-1R1

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
16177

Content And Storage:
4° C

Isotype:
IgG2a