FERMA549058
Leptin Receptor Monoclonal Antibody (2F1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | FERMA549058-Each-of-1 | In Stock | ₹ 49,410.90 |
FERMA549058 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,410.90
GST (18%): ₹ 8,893.962
Total Price: ₹ 58,304.862
Antigen
Leptin Receptor
Classification
Monoclonal
Concentration
100 μg/mL
Formulation
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.
P48357
Gene Symbols
Lepr
Immunogen
The monoclonal antibody 2F1 reacts with human soluble leptin receptor (sLR) in plasma
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Inhibition Assays, Western Blot
Clone
2F1
Conjugate
Unconjugated
Gene
Lepr
Gene Alias
B219; CD antigen CD295; CD295; CD295 antigen; db; diabetes; Fa; HuB219; HuB219.2; LEPR; LEP-R; Leprb; LEPRD; LEPROT; leptin receptor; Leptin receptor (fatty); leptin receptor gene-related protein; Modb1; OB receptor; obese-like; obl; Obr; OB-R; OB-RGRP
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
3953
Content And Storage
4° C
Isotype
IgG1
Related Products
Description
- The monoclonal antibody 2F1 specifically reacts with sLR with a molecular mass of 180kD
- The 2F1 antibody can be used to measure in both free sLR and sLR bound to leptin in plasma
- The leptin (OB-R) receptor is a member of the cytokine receptor superfamily which plays an important role in mammalian body weight homeostasis and energy balance
- Ligand-induced activation of the OB-R by the adipose tissue-secreted hormone, leptin, appears to activate downstream signaling events through the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway
- Leptin can homo-dimerize OB-R extracellular domains while downstream signaling events are initiated upon homo-dimerization of OB-R intracellular domains
- Several isoforms of the OB-R which differ in length and signaling capabilities have been reported
- RNA transcripts encoding the OB-R long form have been found in the choroid plexus and in the hypothalamus which has been proposed as a control center for satiety and energy expenditure
- Mutations in either the mouse OB-R (db) or leptin (ob) genes have been shown to result in early-onset obesity
- Metabolic abnormalities attributable to these genotypes include hypercorticoidemia, hyperinsulinemia and insulin resistance, hyperglycemia, altered CNS activity, reduced metabolic rate of brown adipose tissue, and a large increase in white adipose tissue.
Compare Similar Items
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Antigen: Leptin Receptor
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: P48357
Gene Symbols: Lepr
Immunogen: The monoclonal antibody 2F1 reacts with human soluble leptin receptor (sLR) in plasma
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Inhibition Assays, Western Blot
Clone: 2F1
Conjugate: Unconjugated
Gene: Lepr
Gene Alias: B219; CD antigen CD295; CD295; CD295 antigen; db; diabetes; Fa; HuB219; HuB219.2; LEPR; LEP-R; Leprb; LEPRD; LEPROT; leptin receptor; Leptin receptor (fatty); leptin receptor gene-related protein; Modb1; OB receptor; obese-like; obl; Obr; OB-R; OB-RGRP
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 3953
Content And Storage: 4° C
Isotype: IgG1
Antigen:
Leptin Receptor
Classification:
Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
P48357
Gene Symbols:
Lepr
Immunogen:
The monoclonal antibody 2F1 reacts with human soluble leptin receptor (sLR) in plasma
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Inhibition Assays, Western Blot
Clone:
2F1
Conjugate:
Unconjugated
Gene:
Lepr
Gene Alias:
B219; CD antigen CD295; CD295; CD295 antigen; db; diabetes; Fa; HuB219; HuB219.2; LEPR; LEP-R; Leprb; LEPRD; LEPROT; leptin receptor; Leptin receptor (fatty); leptin receptor gene-related protein; Modb1; OB receptor; obese-like; obl; Obr; OB-R; OB-RGRP
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
3953
Content And Storage:
4° C
Isotype:
IgG1
Antigen: LTBR
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 0.1% BSA and no preservative
Gene Accession No.: P50284
Gene Symbols: Ltbr
Immunogen: Drosophila S2 expressed mouse LTbR Ig fusion protein
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Form: Liquid
Applications: Flow Cytometry, Functional Assay, Inhibition Assays, Western Blot
Clone: 5G11
Conjugate: Unconjugated
Gene: Ltbr
Gene Alias: AI256028; CD18; D12S370; LT beta-R; Ltar; LT-beta receptor; LTbetaR; LT-BETA-R; Ltbr; lymphotoxin B receptor; lymphotoxin beta receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); lymphotoxin-beta receptor; TNF receptor-related protein; Tnfbr; TNFCR; TNFR2-RP; TNFR3; TNF-RIII; TNF-R-III; TNFR-III; TNFRrp; TNFR-RP; Tnfrsf3; Tumor necrosis factor C receptor; tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor superfamily member 3; tumor necrosis factor receptor superfamily, member 3; tumor necrosis factor receptor type III
Host Species: Rat
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 17000
Content And Storage: 4° C
Isotype: IgG2a
Antigen:
LTBR
Classification:
Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 0.1% BSA and no preservative
Gene Accession No.:
P50284
Gene Symbols:
Ltbr
Immunogen:
Drosophila S2 expressed mouse LTbR Ig fusion protein
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Liquid
Applications:
Flow Cytometry, Functional Assay, Inhibition Assays, Western Blot
Clone:
5G11
Conjugate:
Unconjugated
Gene:
Ltbr
Gene Alias:
AI256028; CD18; D12S370; LT beta-R; Ltar; LT-beta receptor; LTbetaR; LT-BETA-R; Ltbr; lymphotoxin B receptor; lymphotoxin beta receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); lymphotoxin-beta receptor; TNF receptor-related protein; Tnfbr; TNFCR; TNFR2-RP; TNFR3; TNF-RIII; TNF-R-III; TNFR-III; TNFRrp; TNFR-RP; Tnfrsf3; Tumor necrosis factor C receptor; tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor superfamily member 3; tumor necrosis factor receptor superfamily, member 3; tumor necrosis factor receptor type III
Host Species:
Rat
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
17000
Content And Storage:
4° C
Isotype:
IgG2a
Antigen: Macrophages (Mature)
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: The monoclonal antibody 25F9 recognizes a protein of 86 kD on the cell surface and within the cytoplasm of mature macrophages.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone: 25F9
Conjugate: Unconjugated
Gene: __
Gene Alias: Macrophages; Mature Macrophages
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C
Isotype: IgG1
Antigen:
Macrophages (Mature)
Classification:
Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 0.1% BSA and 0.02% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
The monoclonal antibody 25F9 recognizes a protein of 86 kD on the cell surface and within the cytoplasm of mature macrophages.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
25F9
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
Macrophages; Mature Macrophages
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C
Isotype:
IgG1
Antigen: Macrophages (Mature)
Classification: Monoclonal
Concentration: 100 μg/mL
Formulation: PBS with 1% BSA and 0.02% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: The monoclonal antibody 25F9 recognizes a protein of 86 kD on the cell surface and within the cytoplasm of mature macrophages
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone: 25F9
Conjugate: FITC
Gene: __
Gene Alias: Macrophages; Mature Macrophages
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: 4° C, store in dark
Isotype: IgG1
Antigen:
Macrophages (Mature)
Classification:
Monoclonal
Concentration:
100 μg/mL
Formulation:
PBS with 1% BSA and 0.02% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
The monoclonal antibody 25F9 recognizes a protein of 86 kD on the cell surface and within the cytoplasm of mature macrophages
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
25F9
Conjugate:
FITC
Gene:
__
Gene Alias:
Macrophages; Mature Macrophages
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
4° C, store in dark
Isotype:
IgG1