PA1052
Leptin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA1052-Each-of-1 | In Stock | ₹ 46,416.30 |
PA1052 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,416.30
GST (18%): ₹ 8,354.934
Total Price: ₹ 54,771.234
Antigen
Leptin
Classification
Polyclonal
Formulation
PBS with 0.05% sodium azide
Gene Accession No.
P41159, P41160, Q29406
Gene Symbols
Lep
Immunogen
Synthetic peptide corresponding to residues S(91) R N V I Q I S N D L E N L R D(106) of human Leptin.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Porcine
Product Type
Antibody
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Conjugate
Unconjugated
Gene
Lep
Gene Alias
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
16846, 3952, 396832
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- PA1-052 detects leptin from human, mouse, and porcine samples
- PA1-052 has been successfully used in Western blot and ICC/IF procedures
- By Western blot, this antibody detects an ∽16 kDa protein representing leptin from human serum
- The PA1-052 immunogen is a synthetic peptide corresponding to residues S(91) R N V I Q I S N D L E N L R D(106) of human Leptin
- This sequence is 94% conserved between human and bovine
- Leptin is a 167 amino acid long protein hormone with important effects in regulating body weight, metabolism and reproductive function
- Leptin is approximately 16 kDa in mass and encoded by the obese (ob) gene
- Leptin is expressed predominantly by adipocytes, which fits with the idea that body weight is sensed as the total mass of fat in the body
- Smaller amounts of leptin are also secreted by cells in the epithelium of the stomach and in the placenta
- Leptin receptors are highly expressed in areas of the hypothalamus known to be important in regulating body weight, as well as in T lymphocytes and vascular endothelial cells
- Leptin's effects on body weight are mediated through effects on hypothalamic centers that control feeding behavior and hunger, body temperature and energy expenditure
- Leptin is involved in regulating food intake, energy expenditure, and adiposity through hypothalamic leptin receptors
- Leptin promotes hematopoiesis, angiogenesis, wound healing, inflammation, immune responses, influences pubertal development and fetal growth
- Studies have investigated the role of leptin in obesity, anorexia nervosa, insulin resistance, and hypertension
- Leptin also has thermogenic actions and regulates enzymes of fatty acid oxidation
- Severe hereditary obesity in rodents and humans can be caused by defects in leptin production.
Compare Similar Items
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Antigen: Leptin
Classification: Polyclonal
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: P41159, P41160, Q29406
Gene Symbols: Lep
Immunogen: Synthetic peptide corresponding to residues S(91) R N V I Q I S N D L E N L R D(106) of human Leptin.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Porcine
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Western Blot
Conjugate: Unconjugated
Gene: Lep
Gene Alias: CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 16846, 3952, 396832
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Leptin
Classification:
Polyclonal
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
P41159, P41160, Q29406
Gene Symbols:
Lep
Immunogen:
Synthetic peptide corresponding to residues S(91) R N V I Q I S N D L E N L R D(106) of human Leptin.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Porcine
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Western Blot
Conjugate:
Unconjugated
Gene:
Lep
Gene Alias:
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
16846, 3952, 396832
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Adiponectin
Classification: Polyclonal
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: Q60994
Gene Symbols: ADIPOQ
Immunogen: Synthetic peptides corresponding to the residues E(18) D D V T T T E E L A P A L V(32) and F(187) T Y D Q Y Q E K N V D Q A(200) of mouse Adiponectin.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Gene: ADIPOQ
Gene Alias: 30 kDa adipocyte complement-related protein; 30kDa; Acdc; Acrp30; Ad; adipo; adipocyte complement related protein; adipocyte complement related protein of 30 kDa; adipocyte complement-related 30 kDa protein; adipocyte complement-related protein of 30 kDa; adipocyte, C1Q and collagen domain containing; adipocyte, C1q and collagen domain-containing protein; Adipocyte-specific protein AdipoQ; adiponectin; adiponectin, C1Q and collagen domain containing; Adipoq; Adipose most abundant gene transcript 1 protein; adipose specific collagen-like factor; ADIPQTL1; ADPIOQ; ADPN; Apm1; APM-1; APN; GBP28; Gelatin-binding protein; gelatin-binding protein 28
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 11450
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Adiponectin
Classification:
Polyclonal
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
Q60994
Gene Symbols:
ADIPOQ
Immunogen:
Synthetic peptides corresponding to the residues E(18) D D V T T T E E L A P A L V(32) and F(187) T Y D Q Y Q E K N V D Q A(200) of mouse Adiponectin.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Gene:
ADIPOQ
Gene Alias:
30 kDa adipocyte complement-related protein; 30kDa; Acdc; Acrp30; Ad; adipo; adipocyte complement related protein; adipocyte complement related protein of 30 kDa; adipocyte complement-related 30 kDa protein; adipocyte complement-related protein of 30 kDa; adipocyte, C1Q and collagen domain containing; adipocyte, C1q and collagen domain-containing protein; Adipocyte-specific protein AdipoQ; adiponectin; adiponectin, C1Q and collagen domain containing; Adipoq; Adipose most abundant gene transcript 1 protein; adipose specific collagen-like factor; ADIPQTL1; ADPIOQ; ADPN; Apm1; APM-1; APN; GBP28; Gelatin-binding protein; gelatin-binding protein 28
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
11450
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: UCP3
Classification: Polyclonal
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: P56499, P56501, Q9N2I9
Gene Symbols: Ucp3
Immunogen: Synthetic peptide corresponding to residues C R(295) A L M K V Q V L R E S P F(308) of mouse and rat UCP-3.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Canine, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: Ucp3
Gene Alias: AI645527; mitochondrial uncoupling protein 3; Slc25a9; solute carrier family 25 member 9; UCP 3; UCP3; UCP-3; uncoupling protein; uncoupling protein 3; uncoupling protein 3 (mitochondrial, proton carrier); uncoupling protein 3, mitochondrial
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22229, 25708, 403575
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
UCP3
Classification:
Polyclonal
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
P56499, P56501, Q9N2I9
Gene Symbols:
Ucp3
Immunogen:
Synthetic peptide corresponding to residues C R(295) A L M K V Q V L R E S P F(308) of mouse and rat UCP-3.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Canine, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
Ucp3
Gene Alias:
AI645527; mitochondrial uncoupling protein 3; Slc25a9; solute carrier family 25 member 9; UCP 3; UCP3; UCP-3; uncoupling protein; uncoupling protein 3; uncoupling protein 3 (mitochondrial, proton carrier); uncoupling protein 3, mitochondrial
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22229, 25708, 403575
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: PCSK1
Classification: Polyclonal
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: P63239
Gene Symbols: PCSK1
Immunogen: Synthetic peptide corresponding to residues S(111) V Q K D S A L D L F N D P M W N(127) of mouse PC1.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Applications: Western Blot
Conjugate: Unconjugated
Gene: PCSK1
Gene Alias: Att-1; Bdp; BMIQ12; EC 3.4.21.93; Furin homolog; LOW QUALITY PROTEIN: neuroendocrine convertase 1; NEC 1; NEC1; Nec-1; Neuroendocrine convertase 1; PC1; PC3; PCSK1; Phpp-1; Prohormone convertase 1; prohormone convertase 1/3; prohormone convertase 3; propeptide-processing protease; Proprotein convertase 1; proprotein convertase subtilisin/kexin type 1; Protein convertase subtilisin / kexin type I; Protein convertase subtilisin / kexin, type I; SPC3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18548
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
PCSK1
Classification:
Polyclonal
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
P63239
Gene Symbols:
PCSK1
Immunogen:
Synthetic peptide corresponding to residues S(111) V Q K D S A L D L F N D P M W N(127) of mouse PC1.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Applications:
Western Blot
Conjugate:
Unconjugated
Gene:
PCSK1
Gene Alias:
Att-1; Bdp; BMIQ12; EC 3.4.21.93; Furin homolog; LOW QUALITY PROTEIN: neuroendocrine convertase 1; NEC 1; NEC1; Nec-1; Neuroendocrine convertase 1; PC1; PC3; PCSK1; Phpp-1; Prohormone convertase 1; prohormone convertase 1/3; prohormone convertase 3; propeptide-processing protease; Proprotein convertase 1; proprotein convertase subtilisin/kexin type 1; Protein convertase subtilisin / kexin type I; Protein convertase subtilisin / kexin, type I; SPC3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18548
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid