PA1051
Leptin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PA1051-Each-of-1 | In Stock | ₹ 49,111.44 |
PA1051 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,111.44
GST (18%): ₹ 8,840.059
Total Price: ₹ 57,951.499
Antigen
Leptin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Lep
Gene Alias
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16846, 25608, 3952, 443534
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Concentration
2 mg/mL
Formulation
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.
P41159, P41160, P50596, Q28603
Gene Symbols
Lep
Immunogen
Synthetic peptide corresponding to residues Q(25) K V Q D D T K T L I K T I V T R I N D(44) of mouse Leptin.
Quantity
50 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Ovine, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PA1-051 detects leptin from human, mouse, sheep and rat samples
- PA1-051 has been successfully used in Western blot, immunocytochemistry and immunohistochemistry experiments
- By Western blot, this antibody detects an ∽16 kDa protein representing leptin from 3T3-L1 cell extract
- Immunohistochemical staining of leptin in sheep brain with PA1-051 results in staining of the ventromedial hypothalamus
- The PA1-051 immunogen is a synthetic peptide corresponding to residues Q(25) K V Q D D T K T L I K T I V T R I N D(44) of mouse Leptin
- This sequence is completely conserved between mouse and bovine
- Leptin is a 167 amino acid long protein hormone with important effects in regulating body weight, metabolism and reproductive function
- Leptin is approximately 16 kDa in mass and encoded by the obese (ob) gene
- Leptin is expressed predominantly by adipocytes, which fits with the idea that body weight is sensed as the total mass of fat in the body
- Smaller amounts of leptin are also secreted by cells in the epithelium of the stomach and in the placenta
- Leptin receptors are highly expressed in areas of the hypothalamus known to be important in regulating body weight, as well as in T lymphocytes and vascular endothelial cells
- Leptin's effects on body weight are mediated through effects on hypothalamic centers that control feeding behavior and hunger, body temperature and energy expenditure
- Leptin is involved in regulating food intake, energy expenditure, and adiposity through hypothalamic leptin receptors
- Leptin promotes hematopoiesis, angiogenesis, wound healing, inflammation, immune responses, influences pubertal development and fetal growth
- Studies have investigated the role of leptin in obesity, anorexia nervosa, insulin resistance, and hypertension
- Leptin also has thermogenic actions and regulates enzymes of fatty acid oxidation
- Severe hereditary obesity in rodents and humans can be caused by defects in leptin production.
Compare Similar Items
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Antigen: Leptin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Lep
Gene Alias: CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 16846, 25608, 3952, 443534
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ChIP Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Concentration: 2 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: P41159, P41160, P50596, Q28603
Gene Symbols: Lep
Immunogen: Synthetic peptide corresponding to residues Q(25) K V Q D D T K T L I K T I V T R I N D(44) of mouse Leptin.
Quantity: 50 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Ovine, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Leptin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Lep
Gene Alias:
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
16846, 25608, 3952, 443534
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Frozen), Western Blot
Concentration:
2 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
P41159, P41160, P50596, Q28603
Gene Symbols:
Lep
Immunogen:
Synthetic peptide corresponding to residues Q(25) K V Q D D T K T L I K T I V T R I N D(44) of mouse Leptin.
Quantity:
50 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Ovine, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Leptin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Lep
Gene Alias: CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin
Host Species: Rabbit
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 16846, 3952, 396832
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: __
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: P41159, P41160, Q29406
Gene Symbols: Lep
Immunogen: Synthetic peptide corresponding to residues S(91) R N V I Q I S N D L E N L R D(106) of human Leptin.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Porcine
Product Type: Antibody
Isotype: IgG
Antigen:
Leptin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Lep
Gene Alias:
CD295 antigen; H-Leptin; HuB219; Lep; LEPD; LEP-R; Leptin; leptin (murine obesity homolog); leptin (obesity homolog, mouse); leptin precursor; Method: conceptual translation supplied by author.; OB; obese; obese protein; obese, mouse, homolog of; obesity; obesity factor; obesity protein; OB-R; OBS; truncated leptin
Host Species:
Rabbit
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
16846, 3952, 396832
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
__
Formulation:
PBS with 0.05% sodium azide
Gene Accession No.:
P41159, P41160, Q29406
Gene Symbols:
Lep
Immunogen:
Synthetic peptide corresponding to residues S(91) R N V I Q I S N D L E N L R D(106) of human Leptin.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Porcine
Product Type:
Antibody
Isotype:
IgG
Antigen: Adiponectin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ADIPOQ
Gene Alias: 30 kDa adipocyte complement-related protein; 30kDa; Acdc; Acrp30; Ad; adipo; adipocyte complement related protein; adipocyte complement related protein of 30 kDa; adipocyte complement-related 30 kDa protein; adipocyte complement-related protein of 30 kDa; adipocyte, C1Q and collagen domain containing; adipocyte, C1q and collagen domain-containing protein; Adipocyte-specific protein AdipoQ; adiponectin; adiponectin, C1Q and collagen domain containing; Adipoq; Adipose most abundant gene transcript 1 protein; adipose specific collagen-like factor; ADIPQTL1; ADPIOQ; ADPN; Apm1; APM-1; APN; GBP28; Gelatin-binding protein; gelatin-binding protein 28
Host Species: Rabbit
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 11450
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: Q60994
Gene Symbols: ADIPOQ
Immunogen: Synthetic peptides corresponding to the residues E(18) D D V T T T E E L A P A L V(32) and F(187) T Y D Q Y Q E K N V D Q A(200) of mouse Adiponectin.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Adiponectin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ADIPOQ
Gene Alias:
30 kDa adipocyte complement-related protein; 30kDa; Acdc; Acrp30; Ad; adipo; adipocyte complement related protein; adipocyte complement related protein of 30 kDa; adipocyte complement-related 30 kDa protein; adipocyte complement-related protein of 30 kDa; adipocyte, C1Q and collagen domain containing; adipocyte, C1q and collagen domain-containing protein; Adipocyte-specific protein AdipoQ; adiponectin; adiponectin, C1Q and collagen domain containing; Adipoq; Adipose most abundant gene transcript 1 protein; adipose specific collagen-like factor; ADIPQTL1; ADPIOQ; ADPN; Apm1; APM-1; APN; GBP28; Gelatin-binding protein; gelatin-binding protein 28
Host Species:
Rabbit
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
11450
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
Q60994
Gene Symbols:
ADIPOQ
Immunogen:
Synthetic peptides corresponding to the residues E(18) D D V T T T E E L A P A L V(32) and F(187) T Y D Q Y Q E K N V D Q A(200) of mouse Adiponectin.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: UCP3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ucp3
Gene Alias: AI645527; mitochondrial uncoupling protein 3; Slc25a9; solute carrier family 25 member 9; UCP 3; UCP3; UCP-3; uncoupling protein; uncoupling protein 3; uncoupling protein 3 (mitochondrial, proton carrier); uncoupling protein 3, mitochondrial
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22229, 25708, 403575
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: P56499, P56501, Q9N2I9
Gene Symbols: Ucp3
Immunogen: Synthetic peptide corresponding to residues C R(295) A L M K V Q V L R E S P F(308) of mouse and rat UCP-3.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Canine, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
UCP3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ucp3
Gene Alias:
AI645527; mitochondrial uncoupling protein 3; Slc25a9; solute carrier family 25 member 9; UCP 3; UCP3; UCP-3; uncoupling protein; uncoupling protein 3; uncoupling protein 3 (mitochondrial, proton carrier); uncoupling protein 3, mitochondrial
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22229, 25708, 403575
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.:
P56499, P56501, Q9N2I9
Gene Symbols:
Ucp3
Immunogen:
Synthetic peptide corresponding to residues C R(295) A L M K V Q V L R E S P F(308) of mouse and rat UCP-3.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Canine, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG