FERMA549056

Integrin beta 1 (CD29) Monoclonal Antibody (BV7), FITC, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 FERMA549056-Each-of-1 In Stock ₹ 56,726.28

FERMA549056 - Each of 1

₹ 56,726.28

In Stock

Quantity

1

Base Price: ₹ 56,726.28

GST (18%): ₹ 10,210.73

Total Price: ₹ 66,937.01

Antigen

Integrin beta 1 (CD29)

Classification

Monoclonal

Concentration

100 μg/mL

Formulation

PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.

P05556

Gene Symbols

ITGB1

Immunogen

Human umbilical vein EC

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Flow Cytometry, Functional Assay, Immunoprecipitation, Inhibition Assays, Western Blot

Clone

BV7

Conjugate

FITC

Gene

ITGB1

Gene Alias

4633401G24Rik; AA409975; AA960159; Beta OL; beta oligodendroglia; CD29; CSAT antigen; ENSMUSG00000051907; Fibronectin receptor subunit beta; FNRB; Glycoprotein IIa; Gm9863; gpIIa; integrin beta 1; integrin beta 1 (fibronectin receptor beta); integrin beta 1A precursor; Integrin beta1; integrin beta-1; integrin beta-1 subunit; integrin beta1D; integrin precursor; integrin subunit beta 1; integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, beta 1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITBG1D; ITGB1; JG22 antigen; MDF2; MSK12; RGD-receptor; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLAB; VLA-BETA

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

3688

Content And Storage

4° C, store in dark

Isotype

IgG1

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Description

  • BV7 binds to several other tumor cells (MG3 osteosarcoma, A375 melanoma, MHCC-1410 and Lovo colon carcinoma) but does not affect adhesion to endothelial cells
  • ITGB1 (Integrin Subunit Beta 1, beta1 integrin subunit, GPIIa, CD29) is a 110 kDa cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes
  • ITGB1 forms non-covalently linked heterodimers with at least 6 different alpha chains (alpha1-alpha6, CDa-f) determining the binding properties of beta1 (VLA) integrins
  • ITGB1 is a cell adhesion molecule appearing on platelets, as the common Beta subunit of the very late activation antigen (VLA), and as a component of various protein complexes binding to extracellular matrix proteins
  • Decreased expression of ITGB1 correlates with acquiring multidrug resistance of tumor cells in the presence of anti-tumor drug
  • ITGB1 is up-regulated in leukocytes during emigration and extravascular migration and appear to be critically involved in regulating the immune cell trafficking from blood to tissue
  • Further, ITGB1 also regulates tissue damage and disease symptoms related to inflammatory bowel disease
  • Through an ITGB1-dependent mechanism, fibronectin and type I collagen enhance cytokine secretion of human airway smooth muscle in response to IL-1beta
  • More than 8 beta subunits with numerous splice variant isoforms have been identified in mammals
  • There are two major forms of integrin beta1: beta1A and beta1D, which differ in 13 amino acids
  • The distribution pattern in adult tissues for integrin beta types are mutually exclusive
  • Beta1A is present in all tissues, except cardiac and skeletal muscle which express the beta1D variant.

Compare Similar Items

Show Difference

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Thermo Scientific

FERMA549056

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Antigen:
Integrin beta 1 (CD29)

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 1% BSA and 0.02% sodium azide

Gene Accession No.:
P05556

Gene Symbols:
ITGB1

Immunogen:
Human umbilical vein EC

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Immunoprecipitation, Inhibition Assays, Western Blot

Clone:
BV7

Conjugate:
FITC

Gene:
ITGB1

Gene Alias:
4633401G24Rik; AA409975; AA960159; Beta OL; beta oligodendroglia; CD29; CSAT antigen; ENSMUSG00000051907; Fibronectin receptor subunit beta; FNRB; Glycoprotein IIa; Gm9863; gpIIa; integrin beta 1; integrin beta 1 (fibronectin receptor beta); integrin beta 1A precursor; Integrin beta1; integrin beta-1; integrin beta-1 subunit; integrin beta1D; integrin precursor; integrin subunit beta 1; integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, beta 1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITBG1D; ITGB1; JG22 antigen; MDF2; MSK12; RGD-receptor; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLAB; VLA-BETA

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3688

Content And Storage:
4° C, store in dark

Isotype:
IgG1

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FERMA549057

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Antigen:
Integrin beta 3

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and no preservative

Gene Accession No.:
P05106

Gene Symbols:
ITGB3

Immunogen:
The monoclonal antibody BV4 recognizes human beta3 integrin subunit present in Platelet glycoprotein GPIIb-IIIa (integrin alphaIIb/beta3, CD41/CD61) and in the vitronectin receptor (integrin alphaV/beta3, CD51/CD61)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Functional Assay, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Inhibition Assays, Western Blot

Clone:
BV4

Conjugate:
Unconjugated

Gene:
ITGB3

Gene Alias:
antigen CD61; BDPLT16; BDPLT2; beta3 integrin; CD61; EGK_08849; glycoprotein GPIIIa; glycoprotein IIIa; GP3A; GPIIIa; GT; INGRB3; integrin beta 3; integrin beta 3 (Cd61); integrin beta-3; integrin beta-3 subunit; integrin subunit beta 3; integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGB3; platelet glycoprotein IIIa; platelet glycoprotein IIIa integrin subunit beta 3; platelet gpIIIa; platelet membrane glycoprotein IIIa

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3690

Content And Storage:
4° C

Isotype:
IgG1

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FERMA549058

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Antigen:
Leptin Receptor

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and 0.02% sodium azide

Gene Accession No.:
P48357

Gene Symbols:
Lepr

Immunogen:
The monoclonal antibody 2F1 reacts with human soluble leptin receptor (sLR) in plasma

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Inhibition Assays, Western Blot

Clone:
2F1

Conjugate:
Unconjugated

Gene:
Lepr

Gene Alias:
B219; CD antigen CD295; CD295; CD295 antigen; db; diabetes; Fa; HuB219; HuB219.2; LEPR; LEP-R; Leprb; LEPRD; LEPROT; leptin receptor; Leptin receptor (fatty); leptin receptor gene-related protein; Modb1; OB receptor; obese-like; obl; Obr; OB-R; OB-RGRP

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
3953

Content And Storage:
4° C

Isotype:
IgG1

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FERMA549059

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Antigen:
LTBR

Classification:
Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 0.1% BSA and no preservative

Gene Accession No.:
P50284

Gene Symbols:
Ltbr

Immunogen:
Drosophila S2 expressed mouse LTbR Ig fusion protein

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Applications:
Flow Cytometry, Functional Assay, Inhibition Assays, Western Blot

Clone:
5G11

Conjugate:
Unconjugated

Gene:
Ltbr

Gene Alias:
AI256028; CD18; D12S370; LT beta-R; Ltar; LT-beta receptor; LTbetaR; LT-BETA-R; Ltbr; lymphotoxin B receptor; lymphotoxin beta receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); lymphotoxin-beta receptor; TNF receptor-related protein; Tnfbr; TNFCR; TNFR2-RP; TNFR3; TNF-RIII; TNF-R-III; TNFR-III; TNFRrp; TNFR-RP; Tnfrsf3; Tumor necrosis factor C receptor; tumor necrosis factor receptor 2-related protein; Tumor necrosis factor receptor superfamily member 3; tumor necrosis factor receptor superfamily, member 3; tumor necrosis factor receptor type III

Host Species:
Rat

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
17000

Content And Storage:
4° C

Isotype:
IgG2a