MA3070

Importin beta-1 Monoclonal Antibody (3E9), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA3070-Each-of-1 In Stock ₹ 46,416.30

MA3070 - Each of 1

₹ 46,416.30

In Stock

Quantity

1

Base Price: ₹ 46,416.30

GST (18%): ₹ 8,354.934

Total Price: ₹ 54,771.234

Antigen

Importin beta-1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.05% sodium azide

Gene Accession No.

P52296, P70168, Q14974

Gene Symbols

KPNB1

Immunogen

Purified NTF97 from bovine erythrocytes.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Canine, Human, Mouse, Porcine, Rat

Product Type

Antibody

Isotype

IgG2a

Applications

Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Inhibition Assays, Immunoprecipitation, Western Blot

Clone

3E9

Conjugate

Unconjugated

Gene

KPNB1

Gene Alias

AA409963; HGNC:6400; IMB1; Impnb; importin 1; importin 90; importin beta; importin beta-1 subunit; importin subunit beta-1; Importin-90; IPO1; IPOB; KapB1; karyopherin (importin) beta 1; karyopherin beta 1; karyopherin subunit beta 1; karyopherin subunit beta-1; karyopherin,beta 1; Kpnb1; MGC2155; MGC2156; MGC2157; NTF97; Nuclear factor p97; pore targeting complex 97 kDa subunit; PTAC97; SCG

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

100518449, 16211, 24917, 3837, 491042, 507804

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MA3-070 detects Importin beta 1 from human, canine, bovine, rat and mouse tissues as well as porcine cell lysates
  • Importin beta 1 is also known as NTF97, Nuclear Transport Factor p97, and karyopherin beta 1
  • This antibody does not detect bacterially expressed recombinant NTF97
  • MA3-070 has been successfully used in Western blot, immunofluorescence, and immunoprecipitation procedures
  • By Western blot, this antibody detects a single ∽97 kDa protein representing NTF97 in MDBK cell homogenate
  • Immunofluorescence staining of NTF97 in MDBK cells with MA3-070 results in the labeling of both the nuclear envelope (NE) and the cytoplasm and shows discontinuous, punctate staining along the rim of the NE
  • This antibody can inhibit import of nuclear localization sequence-containing proteins in permeabilized cells
  • The MA3-070 antigen is purified NTF97 from bovine erythrocytes
  • Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope
  • The import of proteins containing a nuclear localization signal requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins
  • Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex
  • In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate
  • Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore
  • Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex
  • The protein encoded by this gene is a member of the importin beta family.

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Thermo Scientific

MA3070

--


Antigen:
Importin beta-1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P52296, P70168, Q14974

Gene Symbols:
KPNB1

Immunogen:
Purified NTF97 from bovine erythrocytes.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Human, Mouse, Porcine, Rat

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Inhibition Assays, Immunoprecipitation, Western Blot

Clone:
3E9

Conjugate:
Unconjugated

Gene:
KPNB1

Gene Alias:
AA409963; HGNC:6400; IMB1; Impnb; importin 1; importin 90; importin beta; importin beta-1 subunit; importin subunit beta-1; Importin-90; IPO1; IPOB; KapB1; karyopherin (importin) beta 1; karyopherin beta 1; karyopherin subunit beta 1; karyopherin subunit beta-1; karyopherin,beta 1; Kpnb1; MGC2155; MGC2156; MGC2157; NTF97; Nuclear factor p97; pore targeting complex 97 kDa subunit; PTAC97; SCG

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100518449, 16211, 24917, 3837, 491042, 507804

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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MA3071D488

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Antigen:
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Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with proprietary stabilizer and 0.02% sodium azide

Gene Accession No.:
__

Gene Symbols:
__

Immunogen:
5-iodouridine covalently coupled to ovalbumin

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
__

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry

Clone:
BU-1

Conjugate:
DyLight 488

Gene:
__

Gene Alias:
5-Bromo-2-deoxyuridine; Bromodeoxyuridine

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
__

Content And Storage:
4° C, do not freeze

Form:
Liquid

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MA3218

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Antigen:
TSH Receptor

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.05% sodium azide

Gene Accession No.:
P16473, Q8SPP9

Gene Symbols:
TSHR

Immunogen:
Purified extracellular domain of recombinant human thyrotropin receptor.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Porcine

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Western Blot

Clone:
49

Conjugate:
Unconjugated

Gene:
TSHR

Gene Alias:
AI481368; CHNG1; hTSHR-I; hypothroid; hyt; LGR3; MGC141920; pet; seven transmembrane helix receptor; thyroid stimulating hormone receptor; thyroid stimulating hormone receptor, isoform 2; thyroid-stimulating hormone receptor; thyroid-stimulating hormone receptor variant; thyrotropin receptor; thyrotropin receptor-I, hTSHR-I; TSHR; TSH-R; TSHR; seven transmembrane domain G protein-coupled receptor; TSHRA

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
397560, 7253

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

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Antigen:
HIP

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites diluted in PBS with 0.05% sodium azide

Gene Accession No.:
P50502, Q5ZLF0, Q99L47

Gene Symbols:
St13

Immunogen:
Recombinant human Hip protein.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Chicken, Human, Mouse, Rabbit

Product Type:
Antibody

Isotype:
IgG

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
2G6

Conjugate:
Unconjugated

Gene:
St13

Gene Alias:
1110007I03Rik; 3110002K08Rik; AAG2; aging-associated protein 2; AW555194; FAM10A1; FAM10A4; heat shock 70kD protein binding protein; hedgehog interacting protein; hedgehog-interacting protein; HHIP; HIP; HOP; Hsc70-interacting protein; Hsp70 interacting protein; Hsp70-interacting protein; HSPABP; HSPABP1; hypothetical protein; p48; PRO0786; Progesterone receptor-associated p48 protein; Protein FAM10A1; Protein ST13 homolog; putative tumor suppressor ST13; RCJMB04_6h13; Renal carcinoma antigen NY-REN-33; SNC6; ST13; ST13 Hsp70 interacting protein; ST13, Hsp70 interacting protein; ST13P5; suppression of tumorigenicity 13; suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein); suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) pseudogene 5; suppression of tumorigenicity 13 (colon carcinoma) Hsp70-interacting protein; suppression of tumorigenicity 13 protein; testis secretory sperm-binding protein Li 233m; UNQ5825/PRO19644

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
100354640, 418003, 6767, 70356

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid