GR37100UG

MilliporeSigma™ anti-Vitamin D Receptor Clone: 9A7γE10.4,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 GR37100UG-Each-of-1 In Stock ₹ 46,364.96

GR37100UG - Each of 1

₹ 46,364.96

In Stock

Quantity

1

Base Price: ₹ 46,364.96

GST (18%): ₹ 8,345.693

Total Price: ₹ 54,710.653

Antigen

Vitamin D Receptor

Classification

Monoclonal

Conjugate

Unconjugated

Host Species

Rat

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Amphibian, Chicken, Hamster, Human, Mouse, Porcine, Rat

Form

Purified

Applications

Gel Supershift, Immunoblot, Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone

9A7γE10.4

Formulation

In 10mM PBS, 0.2% BSA, pH 7.4.

Immunogen

purified, chick intestine vitamin D receptor

Regulatory Status

RUO

Test Specificity

Recognizes both occupied and unoccupied vitamin D receptor in breast carcinomas expressing the vitamin D receptor protein.

Content And Storage

2°C to 8°C

Isotype

IgG1

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Description

  • Specifically detects Vitamin D Receptor Clone: 9A7γE10.4 in Amphibian, Chicken, Hamster, Human, Mouse, Porcine, Rat samples, and it is validated for Gel Supershift, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Immuno Blotting Vitamin D Receptor (VDR) also known as 1,25-dihydroxyvitamin D3 receptor is a member of the nuclear steroid hormone receptor superfamily which regulate gene transcription by interacting with response elements in gene promoters
  • VDR binds with the retinoid X receptor (RXR) from specific DNA sequences in the promoter region of vitamin D response elements (VDREs)
  • VDR has been implicated in a variety of physiological functions including effects on growth and differentiation in normal and malignant cells
  • These effects are mediated through a single ligand, calcitriol
  • Cacitriol the active metabolite of vitamin D is a known regulator of calcium homeostasis but it also has numerous other functions including inhibition of proliferation of cancer cells and suppression of T-cell proliferation and cytokine production
  • Human breast carcinomas, leukemias, and prostatic carcinoma cells all express vitamin D receptor, suggesting that vitamin D may have beneficial actions on various malignancies that may prove useful in chemoprevention and/or differentiation therapy.

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GR37100UG

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Antigen:
Vitamin D Receptor

Classification:
Monoclonal

Conjugate:
Unconjugated

Host Species:
Rat

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Amphibian, Chicken, Hamster, Human, Mouse, Porcine, Rat

Form:
Purified

Applications:
Gel Supershift, Immunoblot, Immunoblot, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
9A7γE10.4

Formulation:
In 10mM PBS, 0.2% BSA, pH 7.4.

Immunogen:
purified, chick intestine vitamin D receptor

Regulatory Status:
RUO

Test Specificity:
Recognizes both occupied and unoccupied vitamin D receptor in breast carcinomas expressing the vitamin D receptor protein.

Content And Storage:
2°C to 8°C

Isotype:
IgG1

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Host Species:
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Primary or Secondary:
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Target Species:
Human

Form:
Liquid

Applications:
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Clone:
GB11

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Immunogen:
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4° C

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IgG1

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