MA124966

beta Amyloid Monoclonal Antibody (DE2B4), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA124966-Each-of-1 In Stock ₹ 51,250.44

MA124966 - Each of 1

₹ 51,250.44

In Stock

Quantity

1

Base Price: ₹ 51,250.44

GST (18%): ₹ 9,225.079

Total Price: ₹ 60,475.519

Antigen

beta Amyloid

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P05067

Gene Symbols

APP

Immunogen

Synthetic peptide corresponding to residues 1-17 of human beta Amyloid.

Quantity

50 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1

Applications

ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

DE2B4

Conjugate

Unconjugated

Gene

APP

Gene Alias

A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; amyloid precursor protein variant 1; amyloid precursor protein variant 2; Amyloid β; amyloid-beta A4 protein; amyloid-beta A4 protein; amyloid beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta amyloid protein; beta amyloid protein precursor; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); Beta-amyloid precursor protein; betaApp; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTF gamma; CTF-alpha; CTFgamma; CVAP; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; OTTHUMP00000096096; P3(40); P3(42); Pan-Abeta; peptidase nexin-II; PN2; PN-II; PreA4; PreA4 751; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2

Host Species

Mouse

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

351

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • Protein digestion pretreatment of paraffin sections using formic acid for 2 - 3 minutes is required prior to staining with MA1-24966
  • Positive Control: Alzheimer's disease brain Amyloid beta peptide (Abeta/Beta-amyloid) is the major constituent of amyloid plaques in the brains of individuals afflicted with Alzheimer's disease
  • Abeta peptide is 40-43 amino acids long and generated from the beta-amyloid precursor protein (beta APP) in a two-step process
  • The first step involves cleavage of the extracellular, amino-terminal domain of beta APP
  • Protein cleavage is performed by an aspartyl protease, beta-secretase (BACE) which is synthesized as a propeptide and must be modified to the mature and active form by the prohormone convertase, furin
  • Beta APP cleavage by the mature form of BACE results in the cellular secretion of a segment of beta APP, and a membrane-bound remnant
  • The remnant protein is processed by another protease, gamma-secretase
  • Gamma-secretase cleaves an intra-membrane site in the carboxyl-terminal domain of beta APP, thus generating the amyloid beta peptide
  • Gamma-secretase is believed to be a multi-subunit complex containing presenilin-1 and 2 as central components
  • The transmembrane glycoprotein, nicastrin, is associated with presinilins and has been found to bind to the carboxyl-terminus of beta APP and helps to modulate the production of the amyloid beta peptide
  • Abeta is an extracellular filamentous protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles
  • Alzheimer’s disease, the most common cause of senile dementia, is characterized by abnormal filamentous protein deposits in the brain
  • Beta amyloid deposits are also detected in Lewy body dementia, Down’s syndrome, amyloidosis (Dutch type), cerebroarterial amyloidosis (cerebral amyloid angiopathy) and in the Guam Parkinson-Dementia complex.

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Img

Thermo Scientific

MA124966

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Antigen:
beta Amyloid

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
P05067

Gene Symbols:
APP

Immunogen:
Synthetic peptide corresponding to residues 1-17 of human beta Amyloid.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
DE2B4

Conjugate:
Unconjugated

Gene:
APP

Gene Alias:
A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; amyloid precursor protein variant 1; amyloid precursor protein variant 2; Amyloid β; amyloid-beta A4 protein; amyloid-beta A4 protein; amyloid beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta amyloid protein; beta amyloid protein precursor; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); Beta-amyloid precursor protein; betaApp; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTF gamma; CTF-alpha; CTFgamma; CVAP; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; OTTHUMP00000096096; P3(40); P3(42); Pan-Abeta; peptidase nexin-II; PN2; PN-II; PreA4; PreA4 751; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
351

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

MA1250

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Antigen:
CHOP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P35638, P35639

Gene Symbols:
DDIT3

Immunogen:
A bacterially expressed, mouse CHOP fusion protein.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
9C8

Conjugate:
Unconjugated

Gene:
DDIT3

Gene Alias:
C/EBP homologous protein; C/EBP homoologous protein 10; C/EBP zeta; C/EBP-homologous protein; C/EBP-homologous protein 10; CCAAT/enhancer-binding protein homologous protein; CEBPZ; CHOP; CHOP10; CHOP-10; Ddit3; DDIT-3; ddit3.L; DNA damage inducible transcript 3; DNA damage inducible transcript 3 L homeolog; DNA damage-inducible transcript 3 protein; DNA-damage inducible transcript 3; DNA-damage-inducible transcript 3; GADD153; growth arrest and DNA damage-inducible; growth arrest and DNA damage-inducible protein GADD153; Growth arrest and DNA-damage-inducible protein GADD153; MGC4154; transcription factor GADD153; Xchop; XELAEV_18013440mg

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
13198, 1649

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA125005

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Antigen:
S100B

Classification:
Monoclonal

Concentration:
13.5 mg/mL

Formulation:
Ascites with 15mM sodium azide

Gene Accession No.:
P02638, P04271, P04631, Q6YNR6

Gene Symbols:
S100B

Immunogen:
Purified, full length, native bovine S100b protein.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Feline, Goat, Human, Ovine, Porcine, Rabbit, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone:
SH-B4

Conjugate:
Unconjugated

Gene:
S100B

Gene Alias:
AI850290; Bpb; hypothetical protein LOC525716; NEF; protein S100-B; S100; S100 calcium binding protein B; S100 calcium binding protein beta (neural); S100 calcium-binding protein B; S100 calcium-binding protein beta (neural); S-100 calcium-binding protein beta subunit; S100 calcium-binding protein, beta (neural); S-100 calcium-binding protein, beta chain; S100 protein beta chain; S-100 protein beta chain; S-100 protein subunit beta; S100 protein, beta polypeptide; S100 protein, beta polypeptide, neural; S100B; S100-B; S100beta; S100P

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
100009495, 100623510, 101099488, 101113190, 102169524, 25742, 491615, 525716, 6285

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

MA125027

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Antigen:
Cytokeratin 5/6/8

Classification:
Monoclonal

Concentration:
3 mg/mL

Formulation:
0.01M PBS with 1% BSA and 15mM sodium azide; pH 7.4

Gene Accession No.:
P02538, P05786, P05787, P11679, P13647, P50446, Q10758, Q4FZU2, Q5XQN5, Q6P6Q2, Q922U2

Gene Symbols:
KRT5, KRT6A, KRT8

Immunogen:
Cytokeratin preparation from human epidermis.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Canine, Chicken, Feline, Fish, Goat, Guinea Pig, Hamster, Human, Mouse, Ovine, Rabbit, Rat, Reptile

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone:
PCK-26

Conjugate:
FITC

Gene:
KRT5

Gene Alias:
2310016L08Rik; 3300001P10Rik; 58 kDa cytokeratin; 60-kDa keratin; AA960620; AL022697; alpha keratin; AU019895; AW146334; Card2; CK5; CK-5; CK6A; CK-6A; CK6C; CK-6C; CK6D; CK-6D; CK-6E; CK8; CK-8; CYK8; CYKER; cytokeratin 5; cytokeratin 6A; cytokeratin 6C; cytokeratin 6D; cytokeratin 8; cytokeratin 8 (370 AA); cytokeratin endo A; cytokeratin type II, component III; cytokeratin-5; Cytokeratin-6A; cytokeratin-6C; Cytokeratin-6D; cytokeratin-6E; cytokeratin-8; Cytokeratin-A; DDD; DDD1; EBS2; EndoA; epidermolysis bullosa simplex 2 Dowling-Meara/Kobner/Weber-Cockayne types; Hom s 5; K2C8; K5; K6A; K6a keratin; K6C; K6D; K8; kamp-keratin derived antimicrobial peptide; KDAMP; Ker2; KERA; keratin 5; keratin 5 (epidermolysis bullosa simplex Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5 (epidermolysis bullosa simplex, Dowling-Meara/Kobner/Weber-Cockayne types); keratin 5, type II; keratin 6 alpha; keratin 6A; keratin 6A, , type II; keratin 6A, type II; keratin 6B; keratin 8; keratin 8, type II; keratin complex 2, basic, gene 5; keratin complex 2, basic, gene 6a; keratin complex 2, basic, gene 6c; keratin complex 2, basic, gene 8; keratin complex 2, gene 6a; keratin IV; keratin K6; keratin K6h; keratin, epidermal type II, K6A; keratin, type II cytoskeletal 5; keratin, type II cytoskeletal 60 kDa, component III; keratin, type II cytoskeletal 6A; keratin, type II cytoskeletal 6C; keratin, type II cytoskeletal 8; keratin, type II cytoskeletal 8-like protein; keratin-5; keratin-6A; Keratin-6-alpha; keratin-6C; keratin-8; KO; Krt-2.8; Krt2-5; Krt2-6; Krt2-6a; Krt2-6c; Krt2-8; KRT5; KRT5A; Krt6; KRT6A; Krt6b; KRT6C; KRT6D; Krt8; LOC683313; LOW QUALITY PROTEIN: keratin, type II cytoskeletal 5; LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8; mK6[a]; MK6a; mK6-alpha; PC3; Sak57; similar to keratin complex 2, basic, gene 6a; Tfip8; tuftelin interacting protein 8; type II alpha-keratin IIA; type II alpha-keratin IIC; type II cytokeratin A (no.8); type-II keratin Kb12; type-II keratin Kb5; Type-II keratin Kb6; type-II keratin Kb8

Host Species:
Mouse

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
100303605, 100348891, 100352658, 100687760, 100715346, 100715629, 100736243, 100759488, 101081312, 101100735, 101110495, 102174931, 102175207, 102182762, 110308, 120093743, 16687, 16691, 25626, 281268, 281269, 369017, 3852, 3853, 3856, 407779, 408041, 426896, 486513, 486523, 614456

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Store in the dark.

Form:
Liquid