OMA103132
Amyloid Precursor Protein Monoclonal Antibody (mAbP2-1), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | OMA103132-Each-of-1 | In Stock | ₹ 46,587.42 |
OMA103132 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,587.42
GST (18%): ₹ 8,385.736
Total Price: ₹ 54,973.156
Antigen
Amyloid Precursor Protein
Classification
Monoclonal
Concentration
1.0 mg/mL
Formulation
PBS with no preservative; pH 7.4
Gene Accession No.
P05067
Gene Symbols
APP
Immunogen
Native, secreted form of APP
Quantity
50 μg
Primary or Secondary
Primary
Target Species
Human, Non-human Primate
Product Type
Antibody
Isotype
IgG1
Applications
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
mAbP2-1
Conjugate
Unconjugated
Gene
APP
Gene Alias
A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; amyloid precursor protein variant 1; amyloid precursor protein variant 2; Amyloid β; amyloid-beta A4 protein; amyloid-beta A4 protein; amyloid beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta amyloid protein; beta amyloid protein precursor; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); Beta-amyloid precursor protein; betaApp; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTF gamma; CTF-alpha; CTFgamma; CVAP; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; OTTHUMP00000096096; P3(40); P3(42); Pan-Abeta; peptidase nexin-II; PN2; PN-II; PreA4; PreA4 751; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
351
Content And Storage
-80° C, Avoid Freeze/Thaw Cycles
Form
Liquid
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Description
- OMA1-03132 detects amyloid precursor protein (APP) from human and monkey tissues
- This antibody is specific for native, non-denatured protein, and does not cross-react with mouse, rat APP or other APP homologs
- OMA1-03132 has been successfully used in Western blot (non-reducing conditions), immunocytochemistry, immunoprecipitation and ELISA procedures
- This antibody does not work in in IHC on paraffin embedded tissues nor does it recognize APP if the samples are boiled in Laemmli (SDS) sample buffer containing a reducing agent such as DTT or β-ME
- Can be used in immunoprecipitation utilizing 25 μg/mL of OMA1-03132 linked sepharose
- OMA1-03132 antigen is the native, secreted form of human APP
- The epitope recognized by OMA1-03132 maps to residues 104-118 of APP Amyloid beta peptide (Abeta/Beta-amyloid) is the major constituent of amyloid plaques in the brains of individuals afflicted with Alzheimer's disease
- Abeta peptide is 40-43 amino acids long and generated from the beta-amyloid precursor protein (beta APP) in a two-step process
- The first step involves cleavage of the extracellular, amino-terminal domain of beta APP
- Protein cleavage is performed by an aspartyl protease, beta-secretase (BACE) which is synthesized as a propeptide and must be modified to the mature and active form by the prohormone convertase, furin
- Beta APP cleavage by the mature form of BACE results in the cellular secretion of a segment of beta APP, and a membrane-bound remnant
- The remnant protein is processed by another protease, gamma-secretase
- Gamma-secretase cleaves an intra-membrane site in the carboxyl-terminal domain of beta APP, thus generating the amyloid beta peptide
- Gamma-secretase is believed to be a multi-subunit complex containing presenilin-1 and 2 as central components
- The transmembrane glycoprotein, nicastrin, is associated with presinilins and has been found to bind to the carboxyl-terminus of beta APP and helps to modulate the production of the amyloid beta peptide
- Abeta is an extracellular filamentous protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles
- Alzheimer’s disease, the most common cause of senile dementia, is characterized by abnormal filamentous protein deposits in the brain
- Beta amyloid deposits are also detected in Lewy body dementia, Down’s syndrome, amyloidosis (Dutch type), cerebroarterial amyloidosis (cerebral amyloid angiopathy) and in the Guam Parkinson-Dementia complex.
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Antigen: Amyloid Precursor Protein
Classification: Monoclonal
Concentration: 1.0 mg/mL
Formulation: PBS with no preservative; pH 7.4
Gene Accession No.: P05067
Gene Symbols: APP
Immunogen: Native, secreted form of APP
Quantity: 50 μg
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG1
Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: mAbP2-1
Conjugate: Unconjugated
Gene: APP
Gene Alias: A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; amyloid precursor protein variant 1; amyloid precursor protein variant 2; Amyloid β; amyloid-beta A4 protein; amyloid-beta A4 protein; amyloid beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta amyloid protein; beta amyloid protein precursor; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); Beta-amyloid precursor protein; betaApp; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTF gamma; CTF-alpha; CTFgamma; CVAP; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; OTTHUMP00000096096; P3(40); P3(42); Pan-Abeta; peptidase nexin-II; PN2; PN-II; PreA4; PreA4 751; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 351
Content And Storage: -80° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Antigen:
Amyloid Precursor Protein
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Formulation:
PBS with no preservative; pH 7.4
Gene Accession No.:
P05067
Gene Symbols:
APP
Immunogen:
Native, secreted form of APP
Quantity:
50 μg
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG1
Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
mAbP2-1
Conjugate:
Unconjugated
Gene:
APP
Gene Alias:
A4; AAA; ABETA; Abeta40; Abeta42; ABPP; AD1; Adap; AG; AICD-50; AICD-57; AICD-59; AID(50); AID(57); AID(59); Alpha-CTF; Alpha-secretase C-terminal fragment; Alzheimer disease; Alzheimer disease amyloid A4 protein homolog; alzheimer disease amyloid protein; Amyloid; amyloid A4; Amyloid b; Amyloid beta; amyloid beta (A4) precursor protein; amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease); amyloid beta A4 protein; amyloid beta precursor protein; Amyloid intracellular domain 50; Amyloid intracellular domain 57; Amyloid intracellular domain 59; Amyloid precursor protein; amyloid precursor protein variant 1; amyloid precursor protein variant 2; Amyloid β; amyloid-beta A4 protein; amyloid-beta A4 protein; amyloid beta A4 protein; Amyloid-beta precursor protein; Amyloid-beta protein 40; Amyloid-beta protein 42; Amyloidogenic glycoprotein; APP; APP-C57; APP-C59; APP-C99; APPI; appican; beta amyloid protein; beta amyloid protein precursor; beta-amyloid peptide; beta-amyloid peptide(1-40); beta-amyloid peptide(1-42); Beta-amyloid precursor protein; betaApp; Beta-APP40; Beta-APP42; Beta-CTF; Beta-secretase C-terminal fragment; C31; C80; C83; C99; Cerebral vascular amyloid peptide; CTF gamma; CTF-alpha; CTFgamma; CVAP; E030013M08Rik; Gamma-CTF(50); Gamma-CTF(57); Gamma-CTF(59); Gamma-secretase C-terminal fragment 50; Gamma-secretase C-terminal fragment 57; Gamma-secretase C-terminal fragment 59; N-APP; OTTHUMP00000096096; P3(40); P3(42); Pan-Abeta; peptidase nexin-II; PN2; PN-II; PreA4; PreA4 751; protease nexin II; protease nexin-II; S-APP-alpha; S-APP-beta; Soluble APP-alpha; Soluble APP-beta; testicular tissue protein Li 2
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
351
Content And Storage:
-80° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Antigen: Smoothelin
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: P53814, Q921U8
Gene Symbols: SMTN
Immunogen: Cytoskeletal smoothelin extract of chicken gizzard.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Chicken, Feline, Human, Mouse, Non-human Primate, Porcine, Rat
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone: R4A
Conjugate: Unconjugated
Gene: SMTN
Gene Alias: FLJ35365; FLJ38597; smoothelin; smoothelin-B; smsmo; SMTN
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 100858894, 101094884, 289734, 29856, 414369, 477542, 6525
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Smoothelin
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
P53814, Q921U8
Gene Symbols:
SMTN
Immunogen:
Cytoskeletal smoothelin extract of chicken gizzard.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Chicken, Feline, Human, Mouse, Non-human Primate, Porcine, Rat
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
R4A
Conjugate:
Unconjugated
Gene:
SMTN
Gene Alias:
FLJ35365; FLJ38597; smoothelin; smoothelin-B; smsmo; SMTN
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
100858894, 101094884, 289734, 29856, 414369, 477542, 6525
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: Cardiotin
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: __
Gene Symbols: __
Immunogen: Total protein extract of chicken gizzard.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Chicken, Feline, Goat, Hamster, Human, Mouse, Non-human Primate, Rabbit, Rat, X. laevis, Zebrafish
Product Type: Antibody
Isotype: IgM
Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone: R2G
Conjugate: Unconjugated
Gene: __
Gene Alias: __
Host Species: Mouse
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
Cardiotin
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
Total protein extract of chicken gizzard.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Chicken, Feline, Goat, Hamster, Human, Mouse, Non-human Primate, Rabbit, Rat, X. laevis, Zebrafish
Product Type:
Antibody
Isotype:
IgM
Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
R2G
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
__
Host Species:
Mouse
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Antigen: NEFM
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.09% sodium azide
Gene Accession No.: O77788, P07197, P12839
Gene Symbols: NEFM, nefm.S
Immunogen: Cytoskeletal preparation of calf brain tissue.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bovine, Hamster, Human, Non-human Primate, Rat, X. laevis
Product Type: Antibody
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone: RNF 403
Conjugate: Unconjugated
Gene: NEFM
Gene Alias: 160 kDa neurofilament protein; major neuronal intermediate filament subunit; medium neurofilament subunit; middle molecular weight neurofilament protein NF-M(2); Nef3; Nefm; nef-m; nefm.S; nefm-a; nefm-b; Neurofilament 3; neurofilament 3 (150kDa medium); neurofilament 3, medium; neurofilament M subunit; neurofilament medium; neurofilament medium polypeptide; neurofilament medium S homeolog; neurofilament medium tail domain; neurofilament protein M; Neurofilament protein, middle polypeptide; neurofilament triplet M protein; neurofilament, medium polypeptide; neurofilament, medium polypeptide 150kDa; neurofilament, medium polypeptide S homeolog; neurofilament-3 (150 kD medium); neurofilament-M; neurofilament-M subunit; neuronal intermediate filament; NF160; NF165; NFM; NF-M; NF-M c-terminus; NF-M protein; NMC; XELAEV_18020229mg
Host Species: Mouse
Purification Method: purified
Regulatory Status: RUO
Gene ID (Entrez): 100773854, 24588, 281347, 397995, 4741, 780230
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Antigen:
NEFM
Classification:
Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.09% sodium azide
Gene Accession No.:
O77788, P07197, P12839
Gene Symbols:
NEFM, nefm.S
Immunogen:
Cytoskeletal preparation of calf brain tissue.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Hamster, Human, Non-human Primate, Rat, X. laevis
Product Type:
Antibody
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot
Clone:
RNF 403
Conjugate:
Unconjugated
Gene:
NEFM
Gene Alias:
160 kDa neurofilament protein; major neuronal intermediate filament subunit; medium neurofilament subunit; middle molecular weight neurofilament protein NF-M(2); Nef3; Nefm; nef-m; nefm.S; nefm-a; nefm-b; Neurofilament 3; neurofilament 3 (150kDa medium); neurofilament 3, medium; neurofilament M subunit; neurofilament medium; neurofilament medium polypeptide; neurofilament medium S homeolog; neurofilament medium tail domain; neurofilament protein M; Neurofilament protein, middle polypeptide; neurofilament triplet M protein; neurofilament, medium polypeptide; neurofilament, medium polypeptide 150kDa; neurofilament, medium polypeptide S homeolog; neurofilament-3 (150 kD medium); neurofilament-M; neurofilament-M subunit; neuronal intermediate filament; NF160; NF165; NFM; NF-M; NF-M c-terminus; NF-M protein; NMC; XELAEV_18020229mg
Host Species:
Mouse
Purification Method:
purified
Regulatory Status:
RUO
Gene ID (Entrez):
100773854, 24588, 281347, 397995, 4741, 780230
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid