MA125500

Agrin Monoclonal Antibody (AGR 131), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA125500-Each-of-1 In Stock ₹ 50,352.06

MA125500 - Each of 1

₹ 50,352.06

In Stock

Quantity

1

Base Price: ₹ 50,352.06

GST (18%): ₹ 9,063.371

Total Price: ₹ 59,415.431

Antigen

Agrin

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.1mM PMSF, 50% glycerol and no preservative; pH 7.2

Gene Accession No.

A2ASQ1, P25304

Gene Symbols

Agrn

Immunogen

Recombinant rat agrin, C-terminal construct.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse, Rat

Product Type

Antibody

Isotype

IgG1

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Radioimmune Assays (RIA), Western Blot

Clone

AGR 131

Conjugate

Unconjugated

Gene

Agrn

Gene Alias

AGR; Agrin; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 22 kDa fragment; Agrin C-terminal 90 kDa fragment; Agrin N-terminal 110 kDa subunit; agrin proteoglycan; Agrn; C22; C90; CMS8; CMSPPD; nmf380; RP23-139J18.2

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

11603, 25592

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

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Description

  • This antibody detects all N1 isoforms, but fails to detect the N4 protein
  • Also, the antibody will detect the X, Y, and Z splice variants
  • Agrin is a molecule that resides in the basal lamina of muscle cells and directs key events in post synaptic differentiation
  • Most notably, Agrin is responsible for the clustering of acetylcholine receptors (AChRs) on the cell surface and their localization to the neuromuscular junction
  • Several Agrin variants have been identified which arise from alternative mRNA splicings
  • Agrin splice forms having inserts at two sites in the carboxy terminus designated &quotey&quote and &quotez&quote display a high affinity for AChRs, while splice forms lacking these inserts associate with AChRs weakly
  • Muscle alpha-dystroglycan has been postulated to be the receptor for the clustering activity of agrin; however, this is a point of contention
  • Tyrosine phosphorylation has been implicated as a required early step in AChR aggregation
  • Interestingly, a unique receptor tyrosine kinase, designated MuSK, has been discovered that interacts with Agrin and is specifically localized to developing muscle.

Compare Similar Items

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Thermo Scientific

MA125500

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Antigen:
Agrin

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1mM PMSF, 50% glycerol and no preservative; pH 7.2

Gene Accession No.:
A2ASQ1, P25304

Gene Symbols:
Agrn

Immunogen:
Recombinant rat agrin, C-terminal construct.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Radioimmune Assays (RIA), Western Blot

Clone:
AGR 131

Conjugate:
Unconjugated

Gene:
Agrn

Gene Alias:
AGR; Agrin; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 22 kDa fragment; Agrin C-terminal 90 kDa fragment; Agrin N-terminal 110 kDa subunit; agrin proteoglycan; Agrn; C22; C90; CMS8; CMSPPD; nmf380; RP23-139J18.2

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
11603, 25592

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

MA125524

--


Antigen:
Thyroid Peroxidase

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
tissue culture supernatant with 0.09% sodium azide

Gene Accession No.:
P07202

Gene Symbols:
TPO

Immunogen:
Thyroid Peroxidase purified from human thyroid microsomes.

Quantity:
250 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Paraffin)

Clone:
MoAb47

Conjugate:
Unconjugated

Gene:
TPO

Gene Alias:
EC 1.11.1; LOW QUALITY PROTEIN: thyroid peroxidase; MSA; TDH2A; thyroid microsomal antigen; thyroid peroxidase; thyroid peroxidase (332 AA); thyroperoxidase; TPO; TPX; TPXEC 1.11.1.8

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
7173

Content And Storage:
4° C, do not freeze

Form:
Liquid

Img

Thermo Scientific

MA125568

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Antigen:
Synaptotagmin 1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1mM PMSF, 50% glycerol and no preservative; pH 7.2

Gene Accession No.:
P21707, P46096, P48018

Gene Symbols:
Syt1, syt1.L

Immunogen:
Rat brain synaptic junctional protein complexes.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Mouse, Rabbit, Rat, Shark, X. laevis

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
ASV30

Conjugate:
Unconjugated

Gene:
Syt1

Gene Alias:
AW124717; DKFZp781D2042; FLJ42519; G630098F17Rik; P65; SV DKFZp781D2042; SV SYT; svp65; Syb1; synaptotagmin 1; synaptotagmin 1 L homeolog; synaptotagmin 2; synaptotagmin I; synaptotagmin I protein; synaptotagmin I variant b; Synaptotagmin II; Synaptotagmin XI; synaptotagmin-1; Synaptotagmin-2; SYT; Syt1; syt1.L; SYT2; SytI; SytII; XELAEV_18022019mg

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100350072, 20979, 25716, 281511, 447431

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

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Thermo Scientific

MA125615

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Antigen:
DC-SIGN

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 5% trehalose and no preservative

Gene Accession No.:
Q9NNX6

Gene Symbols:
CD209

Immunogen:
NIH/3T3 transfectants stably expressing human DC-SIGN1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
120507

Conjugate:
Unconjugated

Gene:
CD209

Gene Alias:
CD209; CD209 antigen; CD209 antigen-like protein A; CD209 molecule; Cd209a; CD209a antigen; CD209a molecule; Cd209d; CD209d antigen; CDSIGN; Cire; CLEC4L; Clec4m; C-type lectin domain family 4 member L; C-type lectin domain family 4, member L; C-type lectin domain family 4, member M; Dcsign; DC-SIGN; DC-SIGN1; Dc-signr; DC-SIGN-related protein; Dendritic cell-specific ICAM-3-grabbing non-integrin; dendritic cell-specific ICAM-3-grabbing non-integrin 1; dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin; dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin; HIV gpl20-binding protein; MGC129965; MGC130443; RGD1561104; SIGN-R1; SIGNR5

Host Species:
Mouse

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
30835

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid