MA125568

Synaptotagmin 1 Monoclonal Antibody (ASV30), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA125568-Each-of-1 In Stock ₹ 51,336.00

MA125568 - Each of 1

₹ 51,336.00

In Stock

Quantity

1

Base Price: ₹ 51,336.00

GST (18%): ₹ 9,240.48

Total Price: ₹ 60,576.48

Antigen

Synaptotagmin 1

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.1mM PMSF, 50% glycerol and no preservative; pH 7.2

Gene Accession No.

P21707, P46096, P48018

Gene Symbols

Syt1, syt1.L

Immunogen

Rat brain synaptic junctional protein complexes.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Bovine, Mouse, Rabbit, Rat, Shark, X. laevis

Product Type

Antibody

Isotype

IgG2a

Applications

Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone

ASV30

Conjugate

Unconjugated

Gene

Syt1

Gene Alias

AW124717; DKFZp781D2042; FLJ42519; G630098F17Rik; P65; SV DKFZp781D2042; SV SYT; svp65; Syb1; synaptotagmin 1; synaptotagmin 1 L homeolog; synaptotagmin 2; synaptotagmin I; synaptotagmin I protein; synaptotagmin I variant b; Synaptotagmin II; Synaptotagmin XI; synaptotagmin-1; Synaptotagmin-2; SYT; Syt1; syt1.L; SYT2; SytI; SytII; XELAEV_18022019mg

Host Species

Mouse

Purification Method

Protein G

Regulatory Status

RUO

Gene ID (Entrez)

100350072, 20979, 25716, 281511, 447431

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Related Products

Img

Thermo Scientific

MA120689

--

Img

Thermo Scientific

MA125500

--

Img

Thermo Scientific

MA146412

--

Img

Thermo Scientific

PA130197

--

Img

Thermo Scientific

MA126001

--

Img

Thermo Scientific

MA123304

--

Img

Thermo Scientific

MA123240

--

Img

Thermo Scientific

MA180729

--

Description

  • Recommended positive controls: Mouse or Rat brain tissue extract.
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • Synaptotagmin 1 is a synaptic vesicle membrane glycoprotein that is widely expressed throughout the CNS and is generally thought to act as the Ca2+ sensor in the regulation of exocytosis and neurotransmitter release
  • Studies indicate that synaptotagmin’s Ca2+ mediated binding of SNAP25 is essential for the Ca2+ dependent triggering of membrane
  • It has been demonstrated that discrete residues within the c(2)b binding domain of synaptotagmin 1 independently specify endocytic rate and synaptic vesicle size
  • Synaptotagmin 1 may have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse
  • Further, Synaptotagmin 1 binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone
  • A Ca(2+)-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has been reported
  • Synaptotagmin 1 can also bind to at least three additional proteins in a Ca(2+)-independent manner; these are neurexins, syntaxin and AP2
  • Diseases associated with the dysfunction of Synaptotagmin 1 include food-borne botulism and infant botulism.

Compare Similar Items

Show Difference

Img

Thermo Scientific

MA125568

--


Antigen:
Synaptotagmin 1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.1mM PMSF, 50% glycerol and no preservative; pH 7.2

Gene Accession No.:
P21707, P46096, P48018

Gene Symbols:
Syt1, syt1.L

Immunogen:
Rat brain synaptic junctional protein complexes.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Bovine, Mouse, Rabbit, Rat, Shark, X. laevis

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
ASV30

Conjugate:
Unconjugated

Gene:
Syt1

Gene Alias:
AW124717; DKFZp781D2042; FLJ42519; G630098F17Rik; P65; SV DKFZp781D2042; SV SYT; svp65; Syb1; synaptotagmin 1; synaptotagmin 1 L homeolog; synaptotagmin 2; synaptotagmin I; synaptotagmin I protein; synaptotagmin I variant b; Synaptotagmin II; Synaptotagmin XI; synaptotagmin-1; Synaptotagmin-2; SYT; Syt1; syt1.L; SYT2; SytI; SytII; XELAEV_18022019mg

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
RUO

Gene ID (Entrez):
100350072, 20979, 25716, 281511, 447431

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

MA125615

--


Antigen:
DC-SIGN

Classification:
Monoclonal

Concentration:
0.5 mg/mL

Formulation:
PBS with 5% trehalose and no preservative

Gene Accession No.:
Q9NNX6

Gene Symbols:
CD209

Immunogen:
NIH/3T3 transfectants stably expressing human DC-SIGN1.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG2b

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Clone:
120507

Conjugate:
Unconjugated

Gene:
CD209

Gene Alias:
CD209; CD209 antigen; CD209 antigen-like protein A; CD209 molecule; Cd209a; CD209a antigen; CD209a molecule; Cd209d; CD209d antigen; CDSIGN; Cire; CLEC4L; Clec4m; C-type lectin domain family 4 member L; C-type lectin domain family 4, member L; C-type lectin domain family 4, member M; Dcsign; DC-SIGN; DC-SIGN1; Dc-signr; DC-SIGN-related protein; Dendritic cell-specific ICAM-3-grabbing non-integrin; dendritic cell-specific ICAM-3-grabbing non-integrin 1; dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin; dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin; HIV gpl20-binding protein; MGC129965; MGC130443; RGD1561104; SIGN-R1; SIGNR5

Host Species:
Mouse

Purification Method:
IgG fraction

Regulatory Status:
RUO

Gene ID (Entrez):
30835

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

MA125778

--


Antigen:
Nucleolin

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
tissue culture supernatant with 30% glycerol and 0.05% sodium azide

Gene Accession No.:
P19338

Gene Symbols:
NCL

Immunogen:
Nuclear matrix extract from human MDCK cells.

Quantity:
25 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG1

Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
4i51

Conjugate:
Unconjugated

Gene:
NCL

Gene Alias:
B530004O11Rik; C23; D0Nds28; D1Nds28; FLJ45706; FLJ59041; Ncl; Nuc; Nucl; nucl antibody; Nucleolin; nucleolin-like protein; Protein C23

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Gene ID (Entrez):
4691, 608445

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Img

Thermo Scientific

MA125840

--


Antigen:
TOLLIP

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q9H0E2, Q9QZ06

Gene Symbols:
TOLLIP

Immunogen:
Recombinant fragment corresponding to residues 1-274 of mouse Tollip.

Quantity:
50 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunoprecipitation, Western Blot

Clone:
Kimmy-2

Conjugate:
Unconjugated

Gene:
TOLLIP

Gene Alias:
4930403G24Rik; 4931428G15Rik; adapter protein; EMBL:AAI33068.1}; FLJ33531; IL-1RAcPIP; toll interacting protein; toll-interacting protein; TOLLIP; tollip {ECO:0000312

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
54472, 54473

Content And Storage:
4° C

Form:
Liquid