MA14998

FceR1 alpha Monoclonal Antibody (CRA2 (AER24)), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA14998-Each-of-1 In Stock ₹ 60,063.12

MA14998 - Each of 1

₹ 60,063.12

In Stock

Quantity

1

Base Price: ₹ 60,063.12

GST (18%): ₹ 10,811.362

Total Price: ₹ 70,874.482

Antigen

FceR1 alpha

Classification

Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and no preservative; pH 7.4

Gene Accession No.

P12319

Gene Symbols

FCER1A

Immunogen

Recombinant extracellular portion of recombinant human FcER1 alpha (corresponds to amino acids Met-26-197 excluding signal peptide 1-25).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG1 κ

Applications

Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone

CRA2 (AER24)

Conjugate

Unconjugated

Gene

FCER1A

Gene Alias

alpha polypeptide; fc epsilon r1; Fc epsilon receptor Ia; Fc epsilon RI alpha-chain; Fc fragment of IgE receptor Ia; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc IgE receptor, alpha polypeptide; Fc receptor, IgE, high affinity I, alpha polypeptide; Fce1a; Fc-epsilon RI-alpha; fcepsilonri; FCER1A; FcERI; Fcr-5; high affinity immunoglobulin epsilon receptor alpha-subunit; high affinity immunoglobulin epsilon receptor subunit alpha; IgE Fc receptor subunit alpha; Iger01; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; RATIGER01; RP11-550P17.3

Host Species

Mouse

Purification Method

purified

Regulatory Status

RUO

Gene ID (Entrez)

2205

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • MA1-4998 detects Fc epsilonR1 alpha from human samples
  • The CRA2 (AER24) monoclonal antibody reacts with the Fc epsilonR1 alpha subunit on a region that overlaps the region of the IgE binding site, thus it competes with IgE for the receptor binding
  • Since MA1-4998 has been successfully used in Western blot, flow cytometry, and immunohistochemistry applications
  • The MA1-4998 immunogen is region of Fc epsilonR1 alpha which overlaps with the IgE binding site
  • The epitope has been mapped to amino acids 110-197
  • FceR1 (Fc epsilonR1 alpha) is a subunit of the high affinity receptor of IgE
  • Fc epsilonR1 alpha is a tetrameric complex consisting of one alpha, one β and two additional subunits
  • The latter two are required for signal transduction activity
  • The Fc epsilonR1 complex plays an important role in triggering allergic responses, and the immunoglobulin epsilon receptor (IgE receptor) is the initiator of the allergic response
  • When two or more high-affinity IgE receptors are brought together by allergen-bound IgE molecules, mediators such as histamine, which are responsible for allergy symptoms, are released
  • The IgE receptor couples allergen and mast cells to initiate the inflammatory responses that are characteristic of disorders such as hay fever and asthma
  • The release of histamine and proteases leads to the synthesis of prostaglandins and leukotrienes-potent effectors of the hypersensitivity response.

Compare Similar Items

Show Difference

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Thermo Scientific

MA14998

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Antigen:
FceR1 alpha

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and no preservative; pH 7.4

Gene Accession No.:
P12319

Gene Symbols:
FCER1A

Immunogen:
Recombinant extracellular portion of recombinant human FcER1 alpha (corresponds to amino acids Met-26-197 excluding signal peptide 1-25).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
CRA2 (AER24)

Conjugate:
Unconjugated

Gene:
FCER1A

Gene Alias:
alpha polypeptide; fc epsilon r1; Fc epsilon receptor Ia; Fc epsilon RI alpha-chain; Fc fragment of IgE receptor Ia; Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide; Fc IgE receptor, alpha polypeptide; Fc receptor, IgE, high affinity I, alpha polypeptide; Fce1a; Fc-epsilon RI-alpha; fcepsilonri; FCER1A; FcERI; Fcr-5; high affinity immunoglobulin epsilon receptor alpha-subunit; high affinity immunoglobulin epsilon receptor subunit alpha; IgE Fc receptor subunit alpha; Iger01; immunoglobulin E receptor, high-affinity, of mast cells, alpha polypeptide; RATIGER01; RP11-550P17.3

Host Species:
Mouse

Purification Method:
purified

Regulatory Status:
RUO

Gene ID (Entrez):
2205

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA1510

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Antigen:
Glucocorticoid Receptor

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide; pH 7.2

Gene Accession No.:
P04150, P06536, P06537, P35547, P49115, P59667

Gene Symbols:
Nr3c1

Immunogen:
Partially purified rat GR.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Guinea Pig, Human, Mouse, Ovine, Rabbit, Rat, Yeast

Product Type:
Antibody

Isotype:
IgG2a

Applications:
Flow Cytometry, Gel Shift, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Immunoprecipitation, Western Blot

Clone:
BuGR2

Conjugate:
Unconjugated

Gene:
Nr3c1

Gene Alias:
cytosolic/nuclear receptor; fb13f09; GCCR; Gcr; GCRST; glucocorticoid nuclear receptor variant 1; glucocorticoid receptor; glucocorticoid receptor 1; glucocorticoid receptor alpha; GR; gr alpha; GR Kit; Grl; Grl1; Grl-1; Nr3c1; Nuclear receptor subfamily 3 group C member 1; nuclear receptor subfamily 3, group C, member 1; nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor); OTTHUMP00000222854; OTTHUMP00000222858; utouto; utut; wu:fb13f09; zgc:113038

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
100008890, 100135583, 14815, 24413, 2908, 443412

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Lyophilized

Img

Thermo Scientific

MA1513

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Antigen:
AHR

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
antibody with 0.05% sodium azide

Gene Accession No.:
P30561, P35869, P41738

Gene Symbols:
AHR

Immunogen:
Synthetic peptide corresponding to residues R(12) K R R K P(17) V(22) K P I P A E G I K(31) of mouse AhR.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG3 κ

Applications:
ChIP Assay, Flow Cytometry, Gel Shift, Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Clone:
RPT9

Conjugate:
Unconjugated

Gene:
AHR

Gene Alias:
Ah; Ah receptor; Ahh; Ahr; Ahre; AH-receptor; aromatic hydrocarbon receptor; aryl hydrocarbon receptor; aryl-hydrocarbon receptor; bHLHe76; Class E basic helix-loop-helix protein 76; dioxin receptor; In

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
11622, 196, 25690

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

MA1517

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Antigen:
Mist1

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
Q7RTS1, Q9QYC3

Gene Symbols:
Bhlha15

Immunogen:
Mouse Mist1, C-terminus residues 175-197.

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG1

Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
6E8/A12/C11P1

Conjugate:
Unconjugated

Gene:
Bhlha15

Gene Alias:
1810009C13Rik; basic helix-loop-helix domain containing, class B, 8; basic helix-loop-helix family member a15; basic helix-loop-helix family, member a15; Basic helix-loop-helix transcription factor (bHlH); bHlH; BHLHA15; BHLHB8; Class A basic helix-loop-helix protein 15; class B basic helix-loop-helix protein 8; class II bHLH protein MIST1; MIST1; MIST-1; Muscle, intestine and stomach expression 1

Host Species:
Mouse

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
168620, 17341

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid