MA1935

CFTR Monoclonal Antibody (CF3), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MA1935-Each-of-1 In Stock ₹ 46,245.18

MA1935 - Each of 1

₹ 46,245.18

In Stock

Quantity

1

Base Price: ₹ 46,245.18

GST (18%): ₹ 8,324.132

Total Price: ₹ 54,569.312

Antigen

CFTR

Classification

Monoclonal

Concentration

Conc. Not Determined

Formulation

ascites with 0.05% sodium azide

Gene Accession No.

P13569, P26361

Gene Symbols

CFTR

Immunogen

Synthetic Peptide: G(103) R I I A S Y D P D N K E E R(117)

Regulatory Status

RUO

Gene ID (Entrez)

1080, 12638

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone

CF3

Conjugate

Unconjugated

Gene

CFTR

Gene Alias

ABC35; Abcc7; ATP Binding Cassette Superfamily C Member 7 (ABCC7); ATP-binding cassette sub-family C member 7; ATP-binding cassette transporter sub-family C member 7; ATP-binding cassette, subfamily c, member 7; AW495489; cAMP-dependent chloride channel; CF; CFTR; CFTR/MRP; Channel conductance-controlling ATPase; cystic fibrosis transmembrane conductance regulator; cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7); cystic fibrosis transmembrane conductance regulator homolog; cystic fibrosis transmembrane conductance regulator homolog; ATP-binding cassette, subfamily c, member 7; dJ760C5.1; MRP7; RGD1561193; tcag7.78; TNR CFTR; TNR-CFTR

Host Species

Mouse

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgM

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Description

  • MA1-935 detects cystic fibrosis transmembrane conductance factor (CFTR) in human and mouse tissues
  • MA1-935 has been successfully used in Western blot, immunofluorescence and immunoprecipitation procedures
  • By Western blot, this antibody detects a single ∽170 kDa protein representing CFTR in T84 whole cell extract
  • Immunofluorescence staining of CFTR in mouse epithelial cells with MA1-935 results in cell surface staining, consistent with localization at the plasma membrane
  • This antibody also detects one or more immunologically related proteins in mouse cell line Heb7a that does not contain CFTR mRNA
  • MA1-935 can also be used to inhibit the epithelial uptake of S
  • typhi in some mouse cell lines
  • MA1-935 immunizing peptide corresponds to amino acid residues 103-117 found in the first extracellular loop of human and rabbit CFTR
  • This sequence is highly conserved in mouse, sheep, cow, and Xenopus laevis
  • Cystic Fibrosis (CF) is a common lethal genetic disease caused by mutations of the gene coding for the cystic fibrosis transmembrane conductance factor, a cAMP regulated chloride channel
  • Approximately 70% of all CF cases share the deletion of a phenylalanine at position 508 (delta F508) which results in abnormal chloride transport
  • Since the CF mutation is lethal, most often by lung and liver disease, it raises the question of why this genetic disease remains as common as it is
  • One possible explanation is that Salmonella typhi has been shown to use CFTR to enter intestinal epithelial cells and that delta F508 heterozygote and homozygote mice showed 86% and 100% reductions in S
  • typhi intestinal submucosal uptake.

Compare Similar Items

Show Difference

Img

Thermo Scientific

MA1935

--


Antigen:
CFTR

Classification:
Monoclonal

Concentration:
Conc. Not Determined

Formulation:
ascites with 0.05% sodium azide

Gene Accession No.:
P13569, P26361

Gene Symbols:
CFTR

Immunogen:
Synthetic Peptide: G(103) R I I A S Y D P D N K E E R(117)

Regulatory Status:
RUO

Gene ID (Entrez):
1080, 12638

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
CF3

Conjugate:
Unconjugated

Gene:
CFTR

Gene Alias:
ABC35; Abcc7; ATP Binding Cassette Superfamily C Member 7 (ABCC7); ATP-binding cassette sub-family C member 7; ATP-binding cassette transporter sub-family C member 7; ATP-binding cassette, subfamily c, member 7; AW495489; cAMP-dependent chloride channel; CF; CFTR; CFTR/MRP; Channel conductance-controlling ATPase; cystic fibrosis transmembrane conductance regulator; cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7); cystic fibrosis transmembrane conductance regulator homolog; cystic fibrosis transmembrane conductance regulator homolog; ATP-binding cassette, subfamily c, member 7; dJ760C5.1; MRP7; RGD1561193; tcag7.78; TNR CFTR; TNR-CFTR

Host Species:
Mouse

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgM

Img

Thermo Scientific

MA1940

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Antigen:
Galectin 3

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% sodium azide

Gene Accession No.:
P08699, P16110, P17931

Gene Symbols:
LGALS3

Immunogen:
Full length recombinant human galectin-3.

Regulatory Status:
RUO

Gene ID (Entrez):
16854, 3958, 83781

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
ELISA, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Clone:
A3A12

Conjugate:
Unconjugated

Gene:
LGALS3

Gene Alias:
35 kDa lectin; advanced glycation end-product receptor 3; AGE-R3; beta-galactosides-binding lectin; carbohydrate-binding protein 35; CBP 35; CBP30; CBP-30; CBP35; epsilon BP; gal3; gal-3; galactose-specific lectin 3; Galactoside-binding protein; GALBP; galectin 3; Galectin3; galectin-3; GALIG; GBP; IgE binding protein; igE-binding protein; L-29; L31; L-31; L-34; L-34 galactoside-binding lectin; Laminin-binding protein; lectin galactoside-binding soluble 3; lectin galactoside-binding soluble 3 protein; lectin L-29; lectin, galactose binding, soluble 3; lectin, galactoside binding soluble 3; lectin, galactoside-binding, soluble, 3; lectin, galactoside-binding, soluble, 3 (galectin 3); LGALS2; Lgals3; MAC2; Mac-2; Mac-2 antigen

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

MA1980

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Antigen:
c-Myc

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P01106

Gene Symbols:
MYC

Immunogen:
Synthetic peptide A(408) E E Q K L I S E E D L L R K R R E Q L K H K L E Q L R N S C A(438) of human c-Myc.

Regulatory Status:
RUO

Gene ID (Entrez):
4609

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
9E10

Conjugate:
Unconjugated

Gene:
MYC

Gene Alias:
AU016757; Avian myelocytomatosis viral (v-myc) oncogene homolog; avian myelocytomatosis viral oncogene homolog; bHLHe39; c Myc; class E basic helix-loop-helix protein 39; cmyc; c-Myc; c-myc epitope tag; c-myc proto-oncogene; mMyc; MRTL; Myc; Myc protein; Myc proto-oncogene protein; MYC proto-oncogene, bHLH transcription factor; Myc2; MYCC; myc-related translation/localization regulatory factor; myelocytomatosis oncogene; myelocytomatosis viral oncogene homolog; Niard; Nird; Proto-oncogene c-Myc; RNCMYC; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene-like protein

Host Species:
Mouse

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1

Img

Thermo Scientific

MA1980A488

--


Antigen:
c-Myc

Classification:
Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1mg/mL BSA and 0.05% sodium azide

Gene Accession No.:
P01106

Gene Symbols:
MYC

Immunogen:
Synthetic peptide A(408) E E Q K L I S E E D L L R K R R E Q L K H K L E Q L R N S C A(438) of human c-Myc

Regulatory Status:
RUO

Gene ID (Entrez):
4609

Content And Storage:
4° C, do not freeze

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Clone:
9E10

Conjugate:
Alexa Fluor 488

Gene:
MYC

Gene Alias:
AU016757; Avian myelocytomatosis viral (v-myc) oncogene homolog; avian myelocytomatosis viral oncogene homolog; bHLHe39; c Myc; class E basic helix-loop-helix protein 39; cmyc; c-Myc; c-myc epitope tag; c-myc proto-oncogene; mMyc; MRTL; Myc; Myc protein; Myc proto-oncogene protein; MYC proto-oncogene, bHLH transcription factor; Myc2; MYCC; myc-related translation/localization regulatory factor; myelocytomatosis oncogene; myelocytomatosis viral oncogene homolog; Niard; Nird; Proto-oncogene c-Myc; RNCMYC; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene-like protein

Host Species:
Mouse

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG1