SPTBN1 Monoclonal Antibody (4C3), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MA3062-Each-of-1 | In Stock | ₹ 44,448.42 |
MA3062 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,448.42
GST (18%): ₹ 8,000.716
Total Price: ₹ 52,449.136
Antigen
SPTBN1
Classification
Monoclonal
Concentration
Conc. Not Determined
Formulation
ascites diluted in PBS with 0.05% sodium azide
Gene Accession No.
Q01082, Q62261
Gene Symbols
SPTBN1
Immunogen
Purified human erythrocyte beta-1 spectrin.
Regulatory Status
RUO
Gene ID (Entrez)
20742, 305614, 6711
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone
4C3
Conjugate
Unconjugated
Gene
SPTBN1
Gene Alias
9930031C03Rik; A2a; a--fodrin; AI842465; AL033301; alpha II spectrin; alpha-fodrin; alpha-II spectrin; alpha-spectrin 2; beta fodrin; beta II spectrin-like (short form); beta-fodrin; beta-G spectrin; beta-I spectrin; Beta-II spectrin; beta-spectrin 1; beta-spectrin 2; beta-spectrin 2, non-erythrocytic; beta-spectrin II; beta-spectrin non-erythrocytic 1; betaSpII; brain alpha-spectrin; brain erythroid spectrin (235E); brain spectrin; bSPII-; cytoskeleton protein; D330027P03Rik; EL3; ELF; elf1; elf3; embryonic liver beta-fodrin; embryonic liver fodrin; embryonic liver fodrin beta chain; epididymis luminal protein 102; erythroid spectrin beta; fodrin alpha chain; Fodrin beta chain; Gm1301; HEL102; HS2; HSPTB1; inhibitory protein factor; IPF; ja; jaundiced; membrane cytoskeletal protein; mKIAA4049; mKIAA4219; noerythroid alpha-spectrin 2; non-erythrocytic; nonerythroid alpha-spectrin 2; non-erythroid spectrin beta; short form of beta II spectrin; Sp beta; spectrin alpha chain, brain; spectrin alpha chain, non-erythrocytic 1; spectrin beta 1; spectrin beta 2; spectrin beta chain, brain 1; spectrin beta chain, erythrocyte; spectrin beta chain, erythrocytic; Spectrin beta chain, non-erythrocytic 1; spectrin beta Tandil; spectrin beta, erythrocytic; spectrin beta, non-erythrocytic 1; spectrin G; spectrin R; spectrin, alpha, non-erythrocytic 1; spectrin, beta, erythrocytic; spectrin, beta, non-erythrocytic 1; spectrin, non-erythroid alpha chain; spectrin, non-erythroid beta chain 1; SPH2; Spna2; Spnb1; Spnb-1; Spnb2; Spnb-2; Spta2; Sptan1; SPTB; SPTB1; Sptb2; Sptbn1
Host Species
Mouse
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG1
Related Products
Description
- MA3-062 detects spectrin from mouse, rat and human erythrocytes, brain and muscle cells
- This antibody has been shown to specifically detect the two known alternatively spliced forms of spectrin, beta-1 epsilon-1, present in erythrocytes, and beta-1 epsilon-2, present in nerve and striated muscle cells
- It does not cross-react with alpha-2 spectrin or either of the fodrin subunits
- MA3-062 has been successfully used in Western blot, immunohistochemistry (paraffin) and immunofluorescence procedures
- By Western blot, this antibody detects a ∽246 kDa protein representing beta-1 spectrin in rat skeletal muscle homogenate
- Immunofluorescence staining of beta-1 spectrin in rat skeletal muscle fibers with MA3-062 results in intense staining of the sarcolemma
- In immunofluorescence, antigen integrity can be compromised if aldehyde fixatives are left in contact with the protein for extended periods of time
- If paraformaldehyde is used as a fixative, exposure should be limited to 5 minutes or less of no more than a 2% solution
- The MA3-062 antigen is purified human erythrocyte beta-1 spectrin
- Spectrin (Sp), the most abundant of the erythrocyte membrane skeleton proteins, helps these cells maintain their characteristic biconcave shape while remaining flexible and elastic
- Erythrocyte Sp is a heterodimer composed of a 280 kDa alpha subunit and a 246 kDa beta subunit which associate in a side-to-side, antiparallel configuration to form a 100 nm rod-like structure
- Sp in other tissues may be composed of distinct but homologous alpha and beta subunits, sometimes referred to as fodrin
- A newly introduced nomenclature designates the Sp subunits of the erythrocyte as alpha-1 and beta-1, and the fodrin subunits as alpha-2 and beta-2
- Alternatively spliced forms of each are designated as epsilon-1, epsilon-2, etc
- (e
- g
- beta-1 epsilon-1).
Compare Similar Items
Show Difference
Antigen: SPTBN1
Classification: Monoclonal
Concentration: Conc. Not Determined
Formulation: ascites diluted in PBS with 0.05% sodium azide
Gene Accession No.: Q01082, Q62261
Gene Symbols: SPTBN1
Immunogen: Purified human erythrocyte beta-1 spectrin.
Regulatory Status: RUO
Gene ID (Entrez): 20742, 305614, 6711
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Clone: 4C3
Conjugate: Unconjugated
Gene: SPTBN1
Gene Alias: 9930031C03Rik; A2a; a--fodrin; AI842465; AL033301; alpha II spectrin; alpha-fodrin; alpha-II spectrin; alpha-spectrin 2; beta fodrin; beta II spectrin-like (short form); beta-fodrin; beta-G spectrin; beta-I spectrin; Beta-II spectrin; beta-spectrin 1; beta-spectrin 2; beta-spectrin 2, non-erythrocytic; beta-spectrin II; beta-spectrin non-erythrocytic 1; betaSpII; brain alpha-spectrin; brain erythroid spectrin (235E); brain spectrin; bSPII-; cytoskeleton protein; D330027P03Rik; EL3; ELF; elf1; elf3; embryonic liver beta-fodrin; embryonic liver fodrin; embryonic liver fodrin beta chain; epididymis luminal protein 102; erythroid spectrin beta; fodrin alpha chain; Fodrin beta chain; Gm1301; HEL102; HS2; HSPTB1; inhibitory protein factor; IPF; ja; jaundiced; membrane cytoskeletal protein; mKIAA4049; mKIAA4219; noerythroid alpha-spectrin 2; non-erythrocytic; nonerythroid alpha-spectrin 2; non-erythroid spectrin beta; short form of beta II spectrin; Sp beta; spectrin alpha chain, brain; spectrin alpha chain, non-erythrocytic 1; spectrin beta 1; spectrin beta 2; spectrin beta chain, brain 1; spectrin beta chain, erythrocyte; spectrin beta chain, erythrocytic; Spectrin beta chain, non-erythrocytic 1; spectrin beta Tandil; spectrin beta, erythrocytic; spectrin beta, non-erythrocytic 1; spectrin G; spectrin R; spectrin, alpha, non-erythrocytic 1; spectrin, beta, erythrocytic; spectrin, beta, non-erythrocytic 1; spectrin, non-erythroid alpha chain; spectrin, non-erythroid beta chain 1; SPH2; Spna2; Spnb1; Spnb-1; Spnb2; Spnb-2; Spta2; Sptan1; SPTB; SPTB1; Sptb2; Sptbn1
Host Species: Mouse
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG1
Antigen: TGN46
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 1mg/mL BSA and 0.05% sodium azide
Gene Accession No.: O43493, P19814
Gene Symbols: Tgoln2
Immunogen: Synthetic peptide corresponding to residues L(18) P S A S K P N N T S S E N N P P(34) C of rat TGN38.
Regulatory Status: RUO
Gene ID (Entrez): 10618, 192152
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Clone: 2F7.1
Conjugate: Unconjugated
Gene: Tgoln2
Gene Alias: AU015504; D6Ertd384e; hTGN48; hTGN51; Tgn38; TGN38 homolog; TGN38A; TGN38B; TGN41; TGN46; TGN48; TGN51; Tgoln1; Tgoln2; Trans-Golgi network glycoprotein 46; Trans-Golgi network glycoprotein 48; Trans-Golgi network glycoprotein 51; Trans-Golgi network integral membrane protein 1; trans-Golgi network integral membrane protein 2; Trans-Golgi network integral membrane protein TGN38; trans-golgi network protein; trans-Golgi network protein (46, 48, 51kD isoforms); trans-golgi network protein 1; trans-golgi network protein 2; trans-Golgi network protein TGN51; Ttgn1; TTGN2
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Non-human Primate, Rat
Product Type: Antibody
Isotype: IgG1
Antigen: Importin beta-1
Classification: Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.05% sodium azide
Gene Accession No.: P52296, P70168, Q14974
Gene Symbols: KPNB1
Immunogen: Purified NTF97 from bovine erythrocytes.
Regulatory Status: RUO
Gene ID (Entrez): 100518449, 16211, 24917, 3837, 491042, 507804
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Inhibition Assays, Immunoprecipitation, Western Blot
Clone: 3E9
Conjugate: Unconjugated
Gene: KPNB1
Gene Alias: AA409963; HGNC:6400; IMB1; Impnb; importin 1; importin 90; importin beta; importin beta-1 subunit; importin subunit beta-1; Importin-90; IPO1; IPOB; KapB1; karyopherin (importin) beta 1; karyopherin beta 1; karyopherin subunit beta 1; karyopherin subunit beta-1; karyopherin,beta 1; Kpnb1; MGC2155; MGC2156; MGC2157; NTF97; Nuclear factor p97; pore targeting complex 97 kDa subunit; PTAC97; SCG
Host Species: Mouse
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Bovine, Canine, Human, Mouse, Porcine, Rat
Product Type: Antibody
Isotype: IgG2a
