MAB994I100
Reovirus Type 3 sigma 1 hemagglutinin, Mouse anti-Virus, Clone: 9BG5, Millipore Sigma™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MAB994I100-Each-of-1 | In Stock | ₹ 41,643.76 |
MAB994I100 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,643.76
GST (18%): ₹ 7,495.877
Total Price: ₹ 49,139.637
Antigen
Reovirus Type 3 sigma 1 hemagglutinin
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols
N/A
Immunogen
Purified reovirus type 3 virons.
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Isotype
IgG2a κ
Applications
Flow Cytometry, Immunofluorescence, Neutralization, Radioimmune Assays (RIA)
Clone
9BG5
Dilution
Immunofluorescence Analysis: A representative lot detected Reovirus Type 3 sigma 1 hemagglutinin in Immunofluorescence applications (Barton, E.S., et. al. (2001). J Biol Chem. 276(3):2200-2211).Radioimmunoassay Analysis: A representative lot detected Reovirus Type 3 sigma 1 hemagglutinin in Radioimmunoassay applications (William, W.V., et. al. (1988). Proc Natl Acad Sci U S A. 85(17):6488-92). Flow Cytometry Analysis: A representative lot detected Reovirus Type 3 sigma 1 hemagglutinin in Flow Cytometry applications (Dietrich, M.H., et. al. (2017). J Virol. 91(4). pii: e01621-16).Neutralizing Analysis: A representative lot neutralized Reovirus Type 3 in Neutralizing applications (William, W.V., et. al. (1988). Proc Natl Acad Sci USA. 85(17):6488-92).
Gene Alias
T3 sigma 1;Reovirus T3 sigma 1
Host Species
Mouse
Molecular Weight of Antigen
N/A
Quantity
100 μg
Research Discipline
Inflammation & Immunology
Target Species
Virus
Form
Purified
Related Products
Description
- Anti-Reovirus Type 3 sigma 1 hemagglutinin, clone 9BG5, Cat
- No
- MAB994-I, is a mouse monoclonal antibody that detects sigma 1 hemagglutinin of Reovirus type 3 and has been tested for use in Flow Cytometry, Radioimmunoassay, Immunofluorescence, and neutralizing applications
- Mammalian reoviruses are nonenveloped viruses with a segmented, double-stranded RNA genome
- Although these viruses can infect most mammalian species, they are usually asymptomatic in human
- In neonatal SCID NOD mice they can cause lethal infection
- Three major reovirus serotypes have been described that are differentiated by the capacity of antisera to neutralize viral infectivity and block hemagglutination
- Type 1 and 3 sigma 1 contain receptor-binding domains in both the tail and head regions and in type 3 sigma 1 tail is shown to bind alpha-linked sialic acid
- Sigma 1 is reported to engage glycan receptors and junctional adhesion molecule-A (JAM-A) and undergoes a conformational change during the proteolytic disassembly of virions to infectious subvirion particles (ISVPs) that accompany cell entry
- Type 3 reovirus is shown to spread to the central nervous system and causes lethal encephalitis in murine models
- Reovirus can also serve an oncolytic function and can hijack the activated Ras signaling pathway of host tumor cells
- It can induce apoptosis in tumor cells through both extrinsic and intrinsic pathways
- In this process viral uncoating is reported to be an essential factor
- Clone 9BG5 is shown to efficiently block HA by strain type 1 Lang (T1L) and ISVPs
- (Ref.: Yang WQ et al
- (2004)
- Clin
- Cancer Res
- 10(24); 8561-8576; Tyler, KL., et al
- (2004)
- J
- Infect
- Dis
- 189(9); 1664-1675; Dietrich, MH., et al
- (2017)
- J
- Virology 91(4); e01621-16).
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Antigen: Reovirus Type 3 sigma 1 hemagglutinin
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: N/A
Immunogen: Purified reovirus type 3 virons.
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2a κ
Applications: Flow Cytometry, Immunofluorescence, Neutralization, Radioimmune Assays (RIA)
Clone: 9BG5
Dilution: Immunofluorescence Analysis: A representative lot detected Reovirus Type 3 sigma 1 hemagglutinin in Immunofluorescence applications (Barton, E.S., et. al. (2001). J Biol Chem. 276(3):2200-2211).Radioimmunoassay Analysis: A representative lot detected Reovirus Type 3 sigma 1 hemagglutinin in Radioimmunoassay applications (William, W.V., et. al. (1988). Proc Natl Acad Sci U S A. 85(17):6488-92). Flow Cytometry Analysis: A representative lot detected Reovirus Type 3 sigma 1 hemagglutinin in Flow Cytometry applications (Dietrich, M.H., et. al. (2017). J Virol. 91(4). pii: e01621-16).Neutralizing Analysis: A representative lot neutralized Reovirus Type 3 in Neutralizing applications (William, W.V., et. al. (1988). Proc Natl Acad Sci USA. 85(17):6488-92).
Gene Alias: T3 sigma 1;Reovirus T3 sigma 1
Host Species: Mouse
Molecular Weight of Antigen: N/A
Quantity: 100 μg
Research Discipline: Inflammation & Immunology
Target Species: Virus
Form: Purified
Antigen:
Reovirus Type 3 sigma 1 hemagglutinin
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
N/A
Immunogen:
Purified reovirus type 3 virons.
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Flow Cytometry, Immunofluorescence, Neutralization, Radioimmune Assays (RIA)
Clone:
9BG5
Dilution:
Immunofluorescence Analysis: A representative lot detected Reovirus Type 3 sigma 1 hemagglutinin in Immunofluorescence applications (Barton, E.S., et. al. (2001). J Biol Chem. 276(3):2200-2211).Radioimmunoassay Analysis: A representative lot detected Reovirus Type 3 sigma 1 hemagglutinin in Radioimmunoassay applications (William, W.V., et. al. (1988). Proc Natl Acad Sci U S A. 85(17):6488-92). Flow Cytometry Analysis: A representative lot detected Reovirus Type 3 sigma 1 hemagglutinin in Flow Cytometry applications (Dietrich, M.H., et. al. (2017). J Virol. 91(4). pii: e01621-16).Neutralizing Analysis: A representative lot neutralized Reovirus Type 3 in Neutralizing applications (William, W.V., et. al. (1988). Proc Natl Acad Sci USA. 85(17):6488-92).
Gene Alias:
T3 sigma 1;Reovirus T3 sigma 1
Host Species:
Mouse
Molecular Weight of Antigen:
N/A
Quantity:
100 μg
Research Discipline:
Inflammation & Immunology
Target Species:
Virus
Form:
Purified
Antigen: Reovirus Type 3 sigma 1 hemagglutinin
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: N/A
Immunogen: Purified reovirus type 3 virons.
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2a κ
Applications: Flow Cytometry, Immunofluorescence, Neutralization, Radioimmune Assays (RIA)
Clone: 9BG5
Dilution: Immunofluorescence Analysis: A representative lot detected Reovirus Type 3 sigma 1 hemagglutinin in Immunofluorescence applications (Barton, E.S., et. al. (2001). J Biol Chem. 276(3):2200-2211).Radioimmunoassay Analysis: A representative lot detected Reovirus Type 3 sigma 1 hemagglutinin in Radioimmunoassay applications (William, W.V., et. al. (1988). Proc Natl Acad Sci U S A. 85(17):6488-92). Flow Cytometry Analysis: A representative lot detected Reovirus Type 3 sigma 1 hemagglutinin in Flow Cytometry applications (Dietrich, M.H., et. al. (2017). J Virol. 91(4). pii: e01621-16).Neutralizing Analysis: A representative lot neutralized Reovirus Type 3 in Neutralizing applications (William, W.V., et. al. (1988). Proc Natl Acad Sci USA. 85(17):6488-92).
Gene Alias: T3 sigma 1;Reovirus T3 sigma 1
Host Species: Mouse
Molecular Weight of Antigen: N/A
Quantity: 25 μg
Research Discipline: Inflammation & Immunology
Target Species: Virus
Form: Purified
Antigen:
Reovirus Type 3 sigma 1 hemagglutinin
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
N/A
Immunogen:
Purified reovirus type 3 virons.
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Flow Cytometry, Immunofluorescence, Neutralization, Radioimmune Assays (RIA)
Clone:
9BG5
Dilution:
Immunofluorescence Analysis: A representative lot detected Reovirus Type 3 sigma 1 hemagglutinin in Immunofluorescence applications (Barton, E.S., et. al. (2001). J Biol Chem. 276(3):2200-2211).Radioimmunoassay Analysis: A representative lot detected Reovirus Type 3 sigma 1 hemagglutinin in Radioimmunoassay applications (William, W.V., et. al. (1988). Proc Natl Acad Sci U S A. 85(17):6488-92). Flow Cytometry Analysis: A representative lot detected Reovirus Type 3 sigma 1 hemagglutinin in Flow Cytometry applications (Dietrich, M.H., et. al. (2017). J Virol. 91(4). pii: e01621-16).Neutralizing Analysis: A representative lot neutralized Reovirus Type 3 in Neutralizing applications (William, W.V., et. al. (1988). Proc Natl Acad Sci USA. 85(17):6488-92).
Gene Alias:
T3 sigma 1;Reovirus T3 sigma 1
Host Species:
Mouse
Molecular Weight of Antigen:
N/A
Quantity:
25 μg
Research Discipline:
Inflammation & Immunology
Target Species:
Virus
Form:
Purified
Antigen: Lefty-1
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Symbols: LEFTY1
Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse Lefty-1 Leu136-Pro368 Accession # Q64280.1
Purification Method: Protein A or G purified from hybridoma culture supernatant
Regulatory Status: RUO
Primary or Secondary: Primary
Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype: IgG2a
Applications: Western Blot
Clone: 146903
Dilution: Western Blot 1 ug/mL
Gene Alias: AI450052, EBAF, Leftb, lefty, lefty-1, Lefty1, Lefty-B, Stra3, TGFB4
Host Species: Rat
Molecular Weight of Antigen: __
Quantity: 25 μg
Research Discipline: __
Target Species: Mouse
Form: Purified
Antigen:
Lefty-1
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Symbols:
LEFTY1
Immunogen:
Mouse myeloma cell line NS0-derived recombinant mouse Lefty-1 Leu136-Pro368 Accession # Q64280.1
Purification Method:
Protein A or G purified from hybridoma culture supernatant
Regulatory Status:
RUO
Primary or Secondary:
Primary
Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype:
IgG2a
Applications:
Western Blot
Clone:
146903
Dilution:
Western Blot 1 ug/mL
Gene Alias:
AI450052, EBAF, Leftb, lefty, lefty-1, Lefty1, Lefty-B, Stra3, TGFB4
Host Species:
Rat
Molecular Weight of Antigen:
__
Quantity:
25 μg
Research Discipline:
__
Target Species:
Mouse
Form:
Purified
Antigen: Bacterial Peptidoglycan
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Ascites fluid, no preservatives. Liquid.
Gene Symbols: __
Immunogen: Insoluble PG obtained by TCA-heat and ethanol extraction of Streptococcus mutans BHT cells.
Purification Method: __
Regulatory Status: __
Primary or Secondary: Primary
Content And Storage: −20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype: IgG1
Applications: Dot Blot, ELISA, Immunocytochemistry
Clone: 3F6B3
Dilution: __
Gene Alias: __
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 100 μL
Research Discipline: __
Target Species: Bacteria
Form: Ascites
Antigen:
Bacterial Peptidoglycan
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Ascites fluid, no preservatives. Liquid.
Gene Symbols:
__
Immunogen:
Insoluble PG obtained by TCA-heat and ethanol extraction of Streptococcus mutans BHT cells.
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
Primary
Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype:
IgG1
Applications:
Dot Blot, ELISA, Immunocytochemistry
Clone:
3F6B3
Dilution:
__
Gene Alias:
__
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
100 μL
Research Discipline:
__
Target Species:
Bacteria
Form:
Ascites