MABC582MI
MilliporeSigma™ Mouse anti-hIAP-1/BIRC3, Clone: 11D12.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABC582MI-Each-of-1 | In Stock | ₹ 41,307.51 |
MABC582MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,307.51
GST (18%): ₹ 7,435.352
Total Price: ₹ 48,742.862
Antigen
hIAP-1/BIRC3
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
BIRC3; API2; IAP1; MIHC; RNF49
Immunogen
GST-tagged recombinant protein corresponding to the BIR 1/2 of human hIAP-1/BIRC3.
Quantity
100 μg
Research Discipline
Apoptosis, Cancer
Gene ID (Entrez)
NP_001156
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG1 κ
Applications
Western Blot
Clone
11D12.1
Gene Accession No.
Q13489
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects hIAP-1/BIRC3 clone: 11D12.1 in Human samples, and it is validated for Western Blotting Baculoviral IAP repeat-containing protein 3 (UniProt Q13489; also known as API2, Apoptosis inhibitor 2, Baculoviral IAP repeat-containing 3, c-IAP2, hIAP-1, hIAP1, IAP homolog C, IAP-1, Inhibitor of apoptosis protein 1, Mammalian IAP homolog C, RING finger protein 49, TNFR2-TRAF-signaling complex protein 1) is encoded by the BIRC3 (also known as API2, AIP1, IAP1, HAIP1, HIAP1, MALT2, MIHC, RNF49) gene (Gene ID 330) in human
- hIAP-1 (c-IAP2) belongs to the inhibitor of apoptosis (IAP) family of proteins characterized by the presence of at least one baculoviral IAP repeat (BIR) domain
- hIAP-1 (c-IAP2 contains three BIR (BIR1/2/3) domains, followed by an UBA (ubiquitin-associated), a CARD (caspase activation and recruitment domain), and a RING (really interesting new gene) domain
- The BIR domains mediate hIAP-1 interaction with various binding partners, such as caspases, other IAP family members, and receptor-associated complexes
- The RING domain and its associated E3 ligase mediates not only the ubiqutination of substrate proteins, such as caspase-3, caspase-7, SMAC/DIABLO, but also self-ubiquitylation
- The UBA domain enables hIAP-1 to engage protein complexes containing poly-ubiquitylated protein(s).
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Antigen: hIAP-1/BIRC3
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: BIRC3; API2; IAP1; MIHC; RNF49
Immunogen: GST-tagged recombinant protein corresponding to the BIR 1/2 of human hIAP-1/BIRC3.
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_001156
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: Western Blot
Clone: 11D12.1
Gene Accession No.: Q13489
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
hIAP-1/BIRC3
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
BIRC3; API2; IAP1; MIHC; RNF49
Immunogen:
GST-tagged recombinant protein corresponding to the BIR 1/2 of human hIAP-1/BIRC3.
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_001156
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
11D12.1
Gene Accession No.:
Q13489
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: Sulf-2
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: SULF2, KIAA1247
Immunogen: Recombinant protein corresponding to Human Sulf-2.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Applications: ELISA, Immunohistochemistry, Western Blot
Clone: 2B4
Gene Accession No.: NP_001155313
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Sulf-2
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
SULF2, KIAA1247
Immunogen:
Recombinant protein corresponding to Human Sulf-2.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Applications:
ELISA, Immunohistochemistry, Western Blot
Clone:
2B4
Gene Accession No.:
NP_001155313
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: TRP1/TYRP1
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2aκ in buffer containing PBS without preservatives.
Gene Symbols: TYRP1, CAS2, TYRP, TYRRP
Immunogen: Whole cells corresponding to human TRP1/TYRP1.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: −20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype: IgG2a κ
Applications: Blocking Assay, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: TA99
Gene Accession No.: NP_000541
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Antigen:
TRP1/TYRP1
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing PBS without preservatives.
Gene Symbols:
TYRP1, CAS2, TYRP, TYRRP
Immunogen:
Whole cells corresponding to human TRP1/TYRP1.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype:
IgG2a κ
Applications:
Blocking Assay, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
TA99
Gene Accession No.:
NP_000541
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Antigen: NOTCH 3/N3ECD
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: NOTCH3, N3ECD
Immunogen: His-tagged recombinant protein corresponding to Human NOTCH 3.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Applications: Immunocytochemistry, Western Blot
Clone: 1E4
Gene Accession No.: NP_000426
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
NOTCH 3/N3ECD
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
NOTCH3, N3ECD
Immunogen:
His-tagged recombinant protein corresponding to Human NOTCH 3.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Western Blot
Clone:
1E4
Gene Accession No.:
NP_000426
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified