MABE1007MI
MilliporeSigma™ Rat anti-TEL-AML1 fusion, Clone: 6F2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABE1007MI-Each-of-1 | In Stock | ₹ 37,453.03 |
MABE1007MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,453.03
GST (18%): ₹ 6,741.545
Total Price: ₹ 44,194.575
Antigen
TEL-AML1 fusion
Classification
Monoclonal
Formulation
Purified rat monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
ETV6; TEL; TEL1; RUNX1; AML1; CBFA2
Immunogen
KLH-conjugated linear peptide corresponding to human TEL-AML1 fusion.
Quantity
50 μL
Research Discipline
Epigenetics and Nuclear Function
Gene ID (Entrez)
NP_001978; NP_001116079
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG2a κ
Applications
ChIP Assay, Flow Cytometry, Western Blot
Clone
6F2
Gene Accession No.
P41212; Q01196
Host Species
Rat
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects TEL-AML1 fusion clone: 6F2 in Human samples, and it is validated for Chromatin Immunoprecipitation, Flow Cytometry, Western Blotting The chimeric transcription factor TEL-AML1 (ETV6-RUNX1) is the result of the reciprocal translocation t(12;21)(p13;q22), the most common structural genomic alteration found in childhood B-cell precursor acute lymphoblastic leukaemia (ALL)
- The runt-homology DNA-binding domain of AML1 retained in the TEL-AML1 mediates the DNA-binding activity of the fusion protein
- The fusion protein not only exhibits altered transcription activity, it also affects normal transcription activity by directly competing against wild-type AML1 for promoter binding, sequestering transcriptional cofactors available for the wild-type protein, as well as dimerizing with wild-type protein.
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Antigen: TEL-AML1 fusion
Classification: Monoclonal
Formulation: Purified rat monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: ETV6; TEL; TEL1; RUNX1; AML1; CBFA2
Immunogen: KLH-conjugated linear peptide corresponding to human TEL-AML1 fusion.
Quantity: 50 μL
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_001978; NP_001116079
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Applications: ChIP Assay, Flow Cytometry, Western Blot
Clone: 6F2
Gene Accession No.: P41212; Q01196
Host Species: Rat
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
TEL-AML1 fusion
Classification:
Monoclonal
Formulation:
Purified rat monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
ETV6; TEL; TEL1; RUNX1; AML1; CBFA2
Immunogen:
KLH-conjugated linear peptide corresponding to human TEL-AML1 fusion.
Quantity:
50 μL
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
NP_001978; NP_001116079
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
ChIP Assay, Flow Cytometry, Western Blot
Clone:
6F2
Gene Accession No.:
P41212; Q01196
Host Species:
Rat
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: pan-ADP-ribose binding reagent
Classification: Polyclonal
Formulation: Purified fromE. coliby Ni-NTA agarose. Supplied in buffer containing 10mM Tris pH 7.5, 0.2M NaCl, 10% Glycerol, 10mM Imidazole, 1mM PMSF, 1mM β-Mercaptoethanol, 10% glycerol without preservatives.
Gene Symbols: __
Immunogen: __
Quantity: 200 μL
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): __
Content And Storage: Stable for one year at -80°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -80°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: __
Applications: Dot Blot
Clone: __
Gene Accession No.: __
Host Species: E. coli
Purification Method: Ni-NTA agarose
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Antigen:
pan-ADP-ribose binding reagent
Classification:
Polyclonal
Formulation:
Purified fromE. coliby Ni-NTA agarose. Supplied in buffer containing 10mM Tris pH 7.5, 0.2M NaCl, 10% Glycerol, 10mM Imidazole, 1mM PMSF, 1mM β-Mercaptoethanol, 10% glycerol without preservatives.
Gene Symbols:
__
Immunogen:
__
Quantity:
200 μL
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
__
Content And Storage:
Stable for one year at -80°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -80°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
__
Applications:
Dot Blot
Clone:
__
Gene Accession No.:
__
Host Species:
E. coli
Purification Method:
Ni-NTA agarose
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Antigen: Tankyrase-2
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: GST-tagged recombinant human Tankyrase-2 fragment from the region between ANK repeats 6 & 8.
Quantity: 100 μg
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_079511
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2b κ
Applications: Western Blot
Clone: 2F5.1
Gene Accession No.: Q9H2K2
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Tankyrase-2
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
GST-tagged recombinant human Tankyrase-2 fragment from the region between ANK repeats 6 & 8.
Quantity:
100 μg
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_079511
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
2F5.1
Gene Accession No.:
Q9H2K2
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: poly-ADP-ribose binding reagent
Classification: Polyclonal
Formulation: Purified fromE. coliby Ni-NTA agarose. Supplied in buffer containing 10mM Tris pH 7.5, 0.2M NaCl, 10% Glycerol, 10mM Imidazole, 1mM PMSF, 1mM β-Mercaptoethanol, 10% glycerol without preservatives.
Gene Symbols: __
Immunogen: __
Quantity: 200 μL
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): __
Content And Storage: Stable for one year at -80°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -80°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: __
Applications: Dot Blot
Clone: __
Gene Accession No.: __
Host Species: E. coli
Purification Method: Ni-NTA agarose
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Antigen:
poly-ADP-ribose binding reagent
Classification:
Polyclonal
Formulation:
Purified fromE. coliby Ni-NTA agarose. Supplied in buffer containing 10mM Tris pH 7.5, 0.2M NaCl, 10% Glycerol, 10mM Imidazole, 1mM PMSF, 1mM β-Mercaptoethanol, 10% glycerol without preservatives.
Gene Symbols:
__
Immunogen:
__
Quantity:
200 μL
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
__
Content And Storage:
Stable for one year at -80°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -80°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
__
Applications:
Dot Blot
Clone:
__
Gene Accession No.:
__
Host Species:
E. coli
Purification Method:
Ni-NTA agarose
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified