MABE1043MI

MilliporeSigma™ Rat anti-Nup62, Clone: 2A11,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABE1043MI-Each-of-1 In Stock ₹ 36,571.77

MABE1043MI - Each of 1

₹ 36,571.77

In Stock

Quantity

1

Base Price: ₹ 36,571.77

GST (18%): ₹ 6,582.919

Total Price: ₹ 43,154.689

Antigen

Nup62

Classification

Monoclonal

Formulation

Purified rat monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

NUP62

Immunogen

GST-tagged recombinant protein corresponding to aa1-179 of human Nup62.

Quantity

100 μg

Research Discipline

Epigenetics and Nuclear Function

Gene ID (Entrez)

NP_001180286

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG1 κ

Applications

Immunocytochemistry, Western Blot

Clone

2A11

Gene Accession No.

P37198

Host Species

Rat

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

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Description

  • Specifically detects Nup62 clone: 2A11 in Human samples, and it is validated for Immunocytochemistry, Western Blotting Nuclear pore glycoprotein p62 (UniProt P37198; also known as 62kDa nucleoporin, Nucleoporin Nup62) is encoded by the NUP62 (Also known as IBSN, SNDI) gene in human (Gene ID 23636)
  • The nuclear pore complex (NPC) acts as a passageway for nucleocytoplasmic transport
  • Soluble cargo-protein complexes navigate through the pore by binding to phenylalanine-glycine (FG)-repeat proteins attached to the channel walls
  • The Nup62 complex is located in the center of the NPC and contains the FG-repeat proteins Nup62, Nup54, and Nup58 associated with each other via conserved coiled-coil segments in a 1:1:1 stiochiometric ratio
  • The nuclear envelope breaks down during prometaphase
  • The disassembled nucleoporin subcomplexes act as critical regulators of various mitotic events to ensure proper chromosome segregation
  • Specifically, Nup62 is reported to localize to centrosomes/spindle poles, where it associates with the centrosomal proteins gamma-tubulin and hSAS-6
  • Nup62 is involved in the recruitment of critical proteins to the centrosome and its depletion results in mislocalization of several centrosomal components.

Compare Similar Items

Show Difference

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MilliporeSigma™

MABE1043MI

--


Antigen:
Nup62

Classification:
Monoclonal

Formulation:
Purified rat monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
NUP62

Immunogen:
GST-tagged recombinant protein corresponding to aa1-179 of human Nup62.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_001180286

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Western Blot

Clone:
2A11

Gene Accession No.:
P37198

Host Species:
Rat

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma™

MABE1044MI

--


Antigen:
PARP10/ARTD10

Classification:
Monoclonal

Formulation:
Purified rat monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
PARP10

Immunogen:
GST-tagged recombinant protein corresponding to the Glycine-rich region of human PARP10/ARTD10.

Quantity:
100 μg

Research Discipline:
Epigenetics, Nuclear Function

Gene ID (Entrez):
NP_116178

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Western Blot

Clone:
5H11

Gene Accession No.:
Q53GL7

Host Species:
Rat

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma™

MABE1045MI

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Antigen:
CTIP2/BCL11B

Classification:
Monoclonal

Formulation:
Purified rat monoclonal antibody IgG2a in buffer containing 150mM NaCl, 15mM HEPES, pH 7.5, with 0.02% Sodium Azide.

Gene Symbols:
__

Immunogen:
GST-tagged recombinant full-length mouse CTIP2 Beta isoform (Senawong, T., et al. (2003). J. Biol. Chem. 278(44):43041-43050).

Quantity:
100 μg

Research Discipline:
Epigenetics & Nuclear Function

Gene ID (Entrez):
NP_067374

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2a

Applications:
Western Blot

Clone:
25B6

Gene Accession No.:
Q99PV8

Host Species:
Rat

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

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MABE1052MI

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Antigen:
GMPS

Classification:
Monoclonal

Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Symbols:
__

Immunogen:
GST-tagged recombinant human GMPS ATP-PPase domain fragment.

Quantity:
100 μL

Research Discipline:
Epigenetics & Nuclear Function

Gene ID (Entrez):
NP_003866

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
1G6.1

Gene Accession No.:
P49915

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified