MABE1040MI

MilliporeSigma™ Rat anti-Nup98, Clone: 2H10,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABE1040MI-Each-of-1 In Stock ₹ 34,965.81

MABE1040MI - Each of 1

₹ 34,965.81

In Stock

Quantity

1

Base Price: ₹ 34,965.81

GST (18%): ₹ 6,293.846

Total Price: ₹ 41,259.656

Antigen

Nup98

Classification

Monoclonal

Formulation

Purified rat monoclonal IgG2cκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

NUP98; ADAR2

Immunogen

GST-tagged recombinant protein corresponding to human Nup98 near the N-terminus.

Quantity

100 μg

Research Discipline

Epigenetics and Nuclear Function

Gene ID (Entrez)

NP_005378

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG2c κ

Applications

Immunocytochemistry, Western Blot

Clone

2H10

Gene Accession No.

P52948

Host Species

Rat

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Purified

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Description

  • Specifically detects Nup98 clone: 2H10 in Human, Mouse, Rat samples, and it is validated for Immunocytochemistry, Western Blotting The human gene NUP98 (Gene ID 4928; Also known as ADAR2, ADIR2, NUP96, NUP196) encodes the nuclear pore complex protein Nup98-Nup96 (UniProt P52948; also known as GLFG-repeat containing nucleoporin, Nup98-Nup96), which is posttranslationally autocleaved to form Nup98 and Nup96
  • Cleavage of the Nup98-96 linkage enhances the interaction between Nup98 and Nup96 and promotes localization of the two proteins to the nuclear pore complex (NPC)
  • An alternative splice event generates a mRNA variant (isoform 3; also known as Nup98-specific 1), which expresses only the Nup98 portion of the Nup98-96 mRNA and allows the independent production of Nup98
  • Unlike Nup96, Nup98 is known to exist in both NPC-bound and non-NPC-associated pool, where it may participate in gene transcription regulations
  • Nup98 is reported to interact with histone-modifying enzymes CBP/p300 and histone deacetylases (HDACs) through its glycine-leucine-phenylalanine-glycine (GLFG) repeats
  • NUP98 gene is also involved in chromosomal translocations, resulting in Nup98 translocation fusions identified as potent transcription factors that induce acute myeloid leukemia (AML) with a particularly poor patient prognosis.

Compare Similar Items

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MilliporeSigma™

MABE1040MI

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Antigen:
Nup98

Classification:
Monoclonal

Formulation:
Purified rat monoclonal IgG2cκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
NUP98; ADAR2

Immunogen:
GST-tagged recombinant protein corresponding to human Nup98 near the N-terminus.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_005378

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2c κ

Applications:
Immunocytochemistry, Western Blot

Clone:
2H10

Gene Accession No.:
P52948

Host Species:
Rat

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Purified

Img

MilliporeSigma™

MABE1041MI

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Antigen:
Pax-9

Classification:
Monoclonal

Formulation:
Purified rat monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
Pax9; Pax-9

Immunogen:
MBP-tagged recombinant protein corresponding to the C-terminal region of mouse Pax-9.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_035171

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
7C2 (P9C23)

Gene Accession No.:
P47242

Host Species:
Rat

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Purified

Img

MilliporeSigma™

MABE1043MI

--


Antigen:
Nup62

Classification:
Monoclonal

Formulation:
Purified rat monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
NUP62

Immunogen:
GST-tagged recombinant protein corresponding to aa1-179 of human Nup62.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_001180286

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Western Blot

Clone:
2A11

Gene Accession No.:
P37198

Host Species:
Rat

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma™

MABE1044MI

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Antigen:
PARP10/ARTD10

Classification:
Monoclonal

Formulation:
Purified rat monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
PARP10

Immunogen:
GST-tagged recombinant protein corresponding to the Glycine-rich region of human PARP10/ARTD10.

Quantity:
100 μg

Research Discipline:
Epigenetics, Nuclear Function

Gene ID (Entrez):
NP_116178

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Western Blot

Clone:
5H11

Gene Accession No.:
Q53GL7

Host Species:
Rat

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified