MABF204525
Siglec-H, Rat anti-Mouse, Clone: 551, Millipore Sigma™
Manufacturer: Fischer Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABF204525-Each-of-1 | In Stock | ₹ 16,456.61 |
MABF204525 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,456.61
GST (18%): ₹ 2,962.19
Total Price: ₹ 19,418.80
Antigen
Siglec-H
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
Purified rat monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols
Siglech;Siglec-H
Immunogen
Bone marrow-derived Type 1 interferon-producing cells.
Quantity
25 μg
Research Discipline
Inflammation & Immunology
Gene ID (Entrez)
NP_848821.2
Target Species
Mouse
Form
Purified
Applications
Flow Cytometry, Immunohistochemistry
Clone
551
Dilution
Immunohistochemistry Analysis: A representative lot detected Siglec-H in Immunohistochemistry applications (Yun, T.J., et. al. (2016). Cell Metab. 23(5):852-66).Flow Cytometry Analysis: A representative lot detected Siglec-H in Flow Cytometry applications (Yun, T.J., et. al. (2016). Cell Metab. 23(5):852-66).
Gene Alias
Sialic acid binding Ig-like lectin H;Siglech
Host Species
Rat
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 551 is a rat monoclonal antibody that detects murine Siglec-H. It targets an epitope with in the extracellular domain.
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Isotype
IgG1 κ
Related Products
Description
- Anti-Siglec-H, clone 551, Cat
- No
- MABF2045, is a rat monoclonal antibody that detects Sialic acid binding Ig-like lectin H and has been tested for use in Flow Cytometry and Immunohistochemistry
- Siglec-H (UniProt: Q3Y597; also known as Sialic acid binding Ig-like lectin H) is encoded by the Siglech gene (Gene ID: 233274) in murine species
- Siglecs are sialic acid-binding immunoglobulin-like lectins that are expressed mostly in the immune system and may be involved in both adhesive and signaling functions
- Siglec-H is a type I, CD33-related siglec-like transmembrane glycoprotein that is synthesized with a signal peptide (aa 1-18), which is subsequently cleaved off in the mature form
- The mature form has to ig-like domains (aa 32-141 and 151-234) in its extracellular region
- Unlike other CD33-related siglecs, it lacks tyrosine-based signaling motifs in its cytoplasmic tail
- Siglec-H is shown to be expressed on plasmaocytoid dendritic cells (pDCs) and can serve as a reliable marker for these cells
- Siglec-H is also reported to serve as an endocytic receptor expressed on murine pDCs
- Action of Siglec-H depends on a 12 kDa DNAX-activating protein (DAP)
- (Ref.: Zhang, J., et al
- (2006)
- Blood 107(9); 3600-3608; Yun, TJ., et al., (2016), Cell Metabolism 23(5); 852-866).
Compare Similar Items
Show Difference
Antigen: Siglec-H
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Purified rat monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: Siglech;Siglec-H
Immunogen: Bone marrow-derived Type 1 interferon-producing cells.
Quantity: 25 μg
Research Discipline: Inflammation & Immunology
Gene ID (Entrez): NP_848821.2
Target Species: Mouse
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry
Clone: 551
Dilution: Immunohistochemistry Analysis: A representative lot detected Siglec-H in Immunohistochemistry applications (Yun, T.J., et. al. (2016). Cell Metab. 23(5):852-66).Flow Cytometry Analysis: A representative lot detected Siglec-H in Flow Cytometry applications (Yun, T.J., et. al. (2016). Cell Metab. 23(5):852-66).
Gene Alias: Sialic acid binding Ig-like lectin H;Siglech
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 551 is a rat monoclonal antibody that detects murine Siglec-H. It targets an epitope with in the extracellular domain.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
Siglec-H
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified rat monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
Siglech;Siglec-H
Immunogen:
Bone marrow-derived Type 1 interferon-producing cells.
Quantity:
25 μg
Research Discipline:
Inflammation & Immunology
Gene ID (Entrez):
NP_848821.2
Target Species:
Mouse
Form:
Purified
Applications:
Flow Cytometry, Immunohistochemistry
Clone:
551
Dilution:
Immunohistochemistry Analysis: A representative lot detected Siglec-H in Immunohistochemistry applications (Yun, T.J., et. al. (2016). Cell Metab. 23(5):852-66).Flow Cytometry Analysis: A representative lot detected Siglec-H in Flow Cytometry applications (Yun, T.J., et. al. (2016). Cell Metab. 23(5):852-66).
Gene Alias:
Sialic acid binding Ig-like lectin H;Siglech
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 551 is a rat monoclonal antibody that detects murine Siglec-H. It targets an epitope with in the extracellular domain.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: LTBR
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: __
Gene Symbols: Ltbr,Tnfcr,Tnfrsf3
Immunogen: LT betaR-Fc decoy protein.
Quantity: 100 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_034866.1
Target Species: Mouse
Form: Purified
Applications: Inhibition Assays, Flow Cytometry
Clone: 3C8
Dilution: __
Gene Alias: __
Host Species: Rat
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 3C8 detects Tumor necrosis factor receptor superfamily member 3 in NIH3T3 cells.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
LTBR
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
Ltbr,Tnfcr,Tnfrsf3
Immunogen:
LT betaR-Fc decoy protein.
Quantity:
100 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_034866.1
Target Species:
Mouse
Form:
Purified
Applications:
Inhibition Assays, Flow Cytometry
Clone:
3C8
Dilution:
__
Gene Alias:
__
Host Species:
Rat
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 3C8 detects Tumor necrosis factor receptor superfamily member 3 in NIH3T3 cells.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: __
Classification: __
Conjugate: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Applications: __
Clone: __
Dilution: __
Gene Alias: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Isotype: __
Antigen:
__
Classification:
__
Conjugate:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__
Applications:
__
Clone:
__
Dilution:
__
Gene Alias:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Isotype:
__
Antigen: Peripheral Node Addressin (PNAd)
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: __
Gene Symbols: __
Immunogen: Collagenase-dispersed lymph node stromal cells from BALB/c mice.
Quantity: 200 μL
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): __
Target Species: Mouse, Human
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: MECA-79
Dilution: __
Gene Alias: __
Host Species: Rat
Purification Method: Purified by ion-exchange chromatography
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone MECA-79 detects Peripheral Node Addressin (PNAd) in human and mouse.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgM κ
Antigen:
Peripheral Node Addressin (PNAd)
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
__
Immunogen:
Collagenase-dispersed lymph node stromal cells from BALB/c mice.
Quantity:
200 μL
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
__
Target Species:
Mouse, Human
Form:
Purified
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
MECA-79
Dilution:
__
Gene Alias:
__
Host Species:
Rat
Purification Method:
Purified by ion-exchange chromatography
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone MECA-79 detects Peripheral Node Addressin (PNAd) in human and mouse.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgM κ