MABF210325

FcRH5, Mouse anti-Human, Clone: F25, Millipore Sigma™

Manufacturer: Fischer Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 MABF210325-Each-of-1 In Stock ₹ 17,067.51

MABF210325 - Each of 1

₹ 17,067.51

In Stock

Quantity

1

Base Price: ₹ 17,067.51

GST (18%): ₹ 3,072.152

Total Price: ₹ 20,139.662

Antigen

FcRH5

Classification

Monoclonal

Conjugate

Unconjugated

Formulation

Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols

FCRL5;FCRH5;IRTA2;UNQ503/PRO820

Immunogen

Full-length FcRH5 expression plasmid followed by a boost with 293T cells transfected with FcRH5 plasmid.

Quantity

25 μg

Research Discipline

Inflammation & Immunology

Gene ID (Entrez)

NP_112571.2

Target Species

Human

Form

Purified

Applications

ELISA, Flow Cytometry, Western Blot

Clone

F25

Dilution

Flow Cytometry Analysis: A representative lot detected FcRH5 in Flow Cytometry applications (Ise, T., et. al. (2005). Clin Cancer Res. 11(1):87-96).Western Blotting Analysis: A representative lot detected FcRH5 in Western Blotting applications (Ise, T., et. al. (2005). Clin Cancer Res. 11(1):87-96).ELISA Analysis: A representative lot detected FcRH5 in ELISA applications (Ise, T., et. al. (2005). Clin Cancer Res. 11(1):87-96).

Gene Alias

Fc receptor-like protein 5;FcR-like protein 5;FcRL5;BXMAS1;Fc receptor homolog 5;Immune receptor translocation-associated protein 2;IRTA2;CD307e

Host Species

Mouse

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone F25 detects human Fc receptor-like protein 5. It targets an epitope with in the extracellular domain.

Content And Storage

Stable for 1 year at 2-8°C from date of receipt.

Isotype

IgG2a κ

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Description

  • Anti-FcRH5, clone F25, Cat
  • No
  • MABF2103, is a mouse monoclonal antibody that detects Fc receptor-like protein 5 and has been tested for use in ELISA, Flow Cytometry, and Western Blotting
  • Fc receptor-like protein 5 (UniProt: Q96RD9; also known as FcR-like protein 5, FcRL5, BXMAS1, Fc receptor homolog 5, FcRH5, Immune receptor translocation-associated protein 2, IRTA2, CD307e) is encoded by the FCRL5 (also known as FCRH5, IRTA2, UNQ503/PRO820) gene (Gene ID: 83416) in human
  • FcRH5 is a single-pass type I membrane protein that is expressed in marginal zone B-cells, immunoblasts, tonsillar germinal center centrocytes and in the intraepithelial and interfollicular regions of the tonsil
  • It is involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages
  • It is shown to regulate BCR signaling and binds aggregated IgG and engages several of its Ig-domains to bind IgG
  • It is shown to be overexpressed in many lymphoma cell lines and on hairy cell leukemia cells
  • Serum levels of soluble FcRH5 are reported to be elevated in patients with several types of B cell tumors
  • FcRH5 is synthesized with a signal peptide (aa 1-15), which is cleaved off in the mature form that has a long extracellular domain (aa 16-851), a short transmembrane domain (aa 852-872), and a cytoplasmic tail (aa 873-977) that contains immunoreceptor tyrosine-based inhibitor motifs (ITIM)
  • (Ref.: Franco, A., et al
  • (2013)
  • J
  • Immunol
  • 190(11); 5739-46; Ise, T., et al
  • (2007)
  • Leukemia 21(1); 169-174).

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Fischer Scientific

MABF210325

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Antigen:
FcRH5

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
FCRL5;FCRH5;IRTA2;UNQ503/PRO820

Immunogen:
Full-length FcRH5 expression plasmid followed by a boost with 293T cells transfected with FcRH5 plasmid.

Quantity:
25 μg

Research Discipline:
Inflammation & Immunology

Gene ID (Entrez):
NP_112571.2

Target Species:
Human

Form:
Purified

Applications:
ELISA, Flow Cytometry, Western Blot

Clone:
F25

Dilution:
Flow Cytometry Analysis: A representative lot detected FcRH5 in Flow Cytometry applications (Ise, T., et. al. (2005). Clin Cancer Res. 11(1):87-96).Western Blotting Analysis: A representative lot detected FcRH5 in Western Blotting applications (Ise, T., et. al. (2005). Clin Cancer Res. 11(1):87-96).ELISA Analysis: A representative lot detected FcRH5 in ELISA applications (Ise, T., et. al. (2005). Clin Cancer Res. 11(1):87-96).

Gene Alias:
Fc receptor-like protein 5;FcR-like protein 5;FcRL5;BXMAS1;Fc receptor homolog 5;Immune receptor translocation-associated protein 2;IRTA2;CD307e

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone F25 detects human Fc receptor-like protein 5. It targets an epitope with in the extracellular domain.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG2a κ

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MABF2105

clone UMCD6, from mouse...


Antigen:
__

Classification:
__

Conjugate:
__

Formulation:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
__

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
__

Form:
__

Applications:
__

Clone:
__

Dilution:
__

Gene Alias:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Test Specificity:
__

Content And Storage:
__

Isotype:
__

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MABF2105-100

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Antigen:
CD6

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Purified mouse monoclonal antibody IgG1 in PBS without preservatives.

Gene Symbols:
CD6

Immunogen:
ST-1 T cells isolated from human knee synovium.

Quantity:
100 μg

Research Discipline:
Inflammation & Immunology

Gene ID (Entrez):
NP_006716

Target Species:
Human

Form:
Purified

Applications:
Dot Blot, Flow Cytometry, Immunoprecipitation, Functional Assay, Inhibition Assays

Clone:
UMCD6

Dilution:
__

Gene Alias:
T-cell differentiation antigen CD6;T12;TP120

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone UMCD6 specifically detects CD6 in human cells.

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Isotype:
IgG1 κ

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Antigen:
CD6

Classification:
Monoclonal

Conjugate:
Unconjugated

Formulation:
Purified mouse monoclonal antibody IgG1 in PBS without preservatives.

Gene Symbols:
CD6

Immunogen:
ST-1 T cells isolated from human knee synovium.

Quantity:
25 μg

Research Discipline:
Inflammation & Immunology

Gene ID (Entrez):
NP_006716

Target Species:
Human

Form:
Purified

Applications:
Dot Blot, Flow Cytometry, Immunoprecipitation, Functional Assay, Inhibition Assays

Clone:
UMCD6

Dilution:
__

Gene Alias:
T-cell differentiation antigen CD6;T12;TP120

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone UMCD6 specifically detects CD6 in human cells.

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Isotype:
IgG1 κ