MABS181625
LRIG1, Mouse anti-Human, Clone: 2D1.1, Millipore Sigma™
Manufacturer: MilliporeSigma
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS181625-Each-of-1 | In Stock | ₹ 16,456.61 |
MABS181625 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,456.61
GST (18%): ₹ 2,962.19
Total Price: ₹ 19,418.80
Antigen
LRIG1
Classification
Monoclonal
Conjugate
Unconjugated
Gene Alias
Leucine-rich repeats and immunoglobulin-like domains protein 1;LIG-1
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
2D1.1
Formulation
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols
LRIG1;LIG1
Immunogen
GST/His-tagged recombinant fragment corresponding to 134 amino acids from the C-terminal end of human Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1).
Quantity
25 μg
Research Discipline
Signaling
Test Specificity
Clone 2D1.1 detects Leucine-rich repeats and immunoglobulin-like domains protein 1 (LIG-1) in human. It targets an epitope within 134 amino acids from the C-terminal end.
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Isotype
IgG1
Description
- Anti-LRIG1 Antibody, clone 2D1.1, Cat
- No
- MABS1816, is a mouse monoclonal antibody that targets human Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1) and has been tested for use in Western Blotting
- Leucine-rich repeats and immunoglobulin-like domains protein 1 (UniProt: Q96JA1; also known as LIG-1) is encoded by the LRIG1 (also known as LIG1) gene (Gene ID: 26018) in human
- LIG-1 is a widely expressed single-pass type I membrane protein that acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation
- LIG-1 contains 3 Ig-like C2-type (immunoglobulin-like) domains, 15 LRR (leucine-rich) repeats, 1 1 LRRCT domain, and 1LRRNT domain
- The LRRs and the Ig-domains are each sufficient for EGFR/ERBB1 binding and this interaction is abolished only when these two domains are deleted
- LIG-1 is highly expressed by intestinal stem cells and controls the size of the intestinal stem-cell niche by regulating the amplitude of growth-factor signaling
- It is also reported to control stem-cell proliferation in epidermis
- LIG-1 is reported to be expressed in a gradient with highest levels in intestinal stem cells and it is absent from Paneth cells
- About one-third of all cells in the intestinal crypts are shown to express LIG-1
- (Ref.: Wong VWY., et al
- (2012)
- Nat
- Cell Biol
- 14(4); 401-408).
Compare Similar Items
Show Difference
Antigen: LRIG1
Classification: Monoclonal
Conjugate: Unconjugated
Gene Alias: Leucine-rich repeats and immunoglobulin-like domains protein 1;LIG-1
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 2D1.1
Formulation: Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: LRIG1;LIG1
Immunogen: GST/His-tagged recombinant fragment corresponding to 134 amino acids from the C-terminal end of human Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1).
Quantity: 25 μg
Research Discipline: Signaling
Test Specificity: Clone 2D1.1 detects Leucine-rich repeats and immunoglobulin-like domains protein 1 (LIG-1) in human. It targets an epitope within 134 amino acids from the C-terminal end.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1
Antigen:
LRIG1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Alias:
Leucine-rich repeats and immunoglobulin-like domains protein 1;LIG-1
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
2D1.1
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
LRIG1;LIG1
Immunogen:
GST/His-tagged recombinant fragment corresponding to 134 amino acids from the C-terminal end of human Leucine-rich repeats and immunoglobulin-like domains protein 1 (LRIG1).
Quantity:
25 μg
Research Discipline:
Signaling
Test Specificity:
Clone 2D1.1 detects Leucine-rich repeats and immunoglobulin-like domains protein 1 (LIG-1) in human. It targets an epitope within 134 amino acids from the C-terminal end.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1
Antigen: OTUD3
Classification: Monoclonal
Conjugate: Unconjugated
Gene Alias: OTU domain-containing protein 3;EC 3.4.19.12
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 12A6.1
Formulation: Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: OTUD3;KIAA0459
Immunogen: GST/His-tagged recombinant fragment corresponding to 115 amino acids from the C-terminal half of human OTU domain-containing protein 3.
Quantity: 25 μg
Research Discipline: Signaling
Test Specificity: Clone 12A6.1 detects OTU domain-containing protein 3 in human cells. It iargets an epitope within 115 amino acids from the C-terminal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
OTUD3
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Alias:
OTU domain-containing protein 3;EC 3.4.19.12
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
12A6.1
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
OTUD3;KIAA0459
Immunogen:
GST/His-tagged recombinant fragment corresponding to 115 amino acids from the C-terminal half of human OTU domain-containing protein 3.
Quantity:
25 μg
Research Discipline:
Signaling
Test Specificity:
Clone 12A6.1 detects OTU domain-containing protein 3 in human cells. It iargets an epitope within 115 amino acids from the C-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: __
Classification: __
Conjugate: __
Gene Alias: __
Host Species: __
Purification Method: __
Regulatory Status: __
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Target Species: __
Form: __
Applications: __
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Isotype: __
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Classification:
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Conjugate:
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Purification Method:
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Regulatory Status:
__
Primary or Secondary:
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Form:
__
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__
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__
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Isotype:
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Antigen: SHMT
Classification: Monoclonal
Conjugate: Unconjugated
Gene Alias: Serine hydroxymethyltransferase mitochondrial;EC: 2.1.2.1;SHMT;Glycine hydroxymethyltransferase;Serine methylase
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 4D2.1
Formulation: Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: SHMT2
Immunogen: GST/His-tagged recombinant fragment corresponding to 107 amino acids from the C-terminal half of human mitochondrial Serine hydroxymethyltransferase.
Quantity: 25 μg
Research Discipline: Signaling
Test Specificity: Clone 4D2.1 detects human mitochondrial Serine hydroxymethyltransferase. It targets an epitope within 107 amino acids from the C-terminal half.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
SHMT
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Alias:
Serine hydroxymethyltransferase mitochondrial;EC: 2.1.2.1;SHMT;Glycine hydroxymethyltransferase;Serine methylase
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
4D2.1
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
SHMT2
Immunogen:
GST/His-tagged recombinant fragment corresponding to 107 amino acids from the C-terminal half of human mitochondrial Serine hydroxymethyltransferase.
Quantity:
25 μg
Research Discipline:
Signaling
Test Specificity:
Clone 4D2.1 detects human mitochondrial Serine hydroxymethyltransferase. It targets an epitope within 107 amino acids from the C-terminal half.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ