MABS200225

mPEG, Mouse anti-All, Clone: 15-2b, Millipore Sigma™

Manufacturer: Fischer Scientific

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Pack Size SKU Availability Price
Each of 1 MABS200225-Each-of-1 In Stock ₹ 16,456.61

MABS200225 - Each of 1

₹ 16,456.61

In Stock

Quantity

1

Base Price: ₹ 16,456.61

GST (18%): ₹ 2,962.19

Total Price: ₹ 19,418.80

Antigen

mPEG

Classification

Monoclonal

Conjugate

Unconjugated

Gene Alias

Methoxy polyethylene glycol

Immunogen

Methoxy PEG covalently conjugated to E.coli beta-glucuronidase.

Quantity

25 μg

Research Discipline

Signaling

Test Specificity

Clone 15-2b specifically detects proteins conjugated with methoxy polyethylene glycol (mPEG).

Content And Storage

Stable for 1 year at 2-8°C from date of receipt.

Isotype

IgG2b κ

Applications

ELISA

Clone

15-2b

Formulation

Purified mouse monoclonal antibody IgG2b in PBS with 0.04% sodium azide.

Host Species

Mouse

Purification Method

Protein A purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

All species

Form

Purified

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Description

  • Anti-mPEG, clone 15-2b, Cat
  • No
  • MABS2002, is a mouse monoclonal antibody that detects methoxy-PEG (mPEG)-conjugated proteins and has been tested for use in ELISA
  • Polyethylene glycols (PEG) are non-toxic, uncharged, hydrophilic long chain polymers with a big exclusion volume in aqueous solutions
  • The covalent attachment of PEG is commonly employed to modify proteins and drugs that can increase their bioavailability and reduce immunogenicity and proteolytic degradation
  • The monomethoxylated form of polyethylene glycol (mPEG) has been widely employed in drug modifications
  • mPEG modification reduces nonspecific binding and prevents recognition by the reticuloendothelial system
  • This monoclonal antibody (clone 15-2b) specifically binds to the terminal methoxy group, but not the backbone of PEG
  • It displays high affinity for the terminal methoxy group and can be easily used as a detection antibody for the quantification of mPEG by ELISA
  • It is also suitable for detection of PEGylated liposomes and nanoparticles
  • The mPEG cell-based competition ELISA can detect lower molecular-weight (< 2 kDa) mPEG molecules even at nanomolar concentration and the assay is not affected by the presence of mouse or human serum
  • In addition, mPEG cell-based ELISA can be useful in determining the pharmacokinetics of a mPEG molecule an animal without the need for any radiolabeling.

Compare Similar Items

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Fischer Scientific

MABS200225

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Antigen:
mPEG

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Alias:
Methoxy polyethylene glycol

Immunogen:
Methoxy PEG covalently conjugated to E.coli beta-glucuronidase.

Quantity:
25 μg

Research Discipline:
Signaling

Test Specificity:
Clone 15-2b specifically detects proteins conjugated with methoxy polyethylene glycol (mPEG).

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG2b κ

Applications:
ELISA

Clone:
15-2b

Formulation:
Purified mouse monoclonal antibody IgG2b in PBS with 0.04% sodium azide.

Host Species:
Mouse

Purification Method:
Protein A purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
All species

Form:
Purified

Img

Fischer Scientific

MABS2026100

--


Antigen:
EphA2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Alias:
Ephrin type-A receptor 2;EC: 2.7.10.1;Epithelial cell kinase;Tyrosine-protein kinase receptor ECK

Immunogen:
KP-2, KP-3, SUIT-2, and MIAPaCa-2 cells.

Quantity:
100 μg

Research Discipline:
Signaling

Test Specificity:
Clone F2-27 specifically detects Ephrin type -A receptor 2 in human.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunoprecipitation, Inhibition Assays

Clone:
F2-27

Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

MABS202625

--


Antigen:
EphA2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Alias:
Ephrin type-A receptor 2;EC: 2.7.10.1;Epithelial cell kinase;Tyrosine-protein kinase receptor ECK

Immunogen:
KP-2, KP-3, SUIT-2, and MIAPaCa-2 cells.

Quantity:
25 μg

Research Discipline:
Signaling

Test Specificity:
Clone F2-27 specifically detects Ephrin type -A receptor 2 in human.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunoprecipitation, Inhibition Assays

Clone:
F2-27

Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

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MABS2034100

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Antigen:
SREBP-1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Alias:
Sterol regulatory element-binding protein 1;Class D basic helix-loop-helix protein 1;bHLHd1;Sterol regulatory element-binding transcription factor 1

Immunogen:
His-tagged recombinant fragment corresponding to 107 amino acids from the N-terminal half of human Sterol regulatory element-binding protein 1 (SREBP-1).

Quantity:
100 μg

Research Discipline:
Signaling

Test Specificity:
Clone 2A4 is a mouse monoclonal antibody that detects Sterol regulatory element-binding protein 1. It targets an epitope within 107 amino acids from the N-terminal half.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
2A4

Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Hamster, Canine, Human

Form:
Purified