MABS819MI

MilliporeSigma™ Rabbit anti-GAPDH (CT), Clone: RM114,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS819MI-Each-of-1 In Stock ₹ 46,715.76

MABS819MI - Each of 1

₹ 46,715.76

In Stock

Quantity

1

Base Price: ₹ 46,715.76

GST (18%): ₹ 8,408.837

Total Price: ₹ 55,124.597

Antigen

GAPDH (CT)

Classification

Monoclonal

Formulation

Rabbit monoclonal in PBS with 1% BSA and 0.09% sodium azide.

Gene Symbols

GAPDH; GAPD; CDABP0047

Immunogen

A peptide corresponding to the C-terminus of GAPDH.

Quantity

100 μL

Research Discipline

Signaling

Target Species

Human

Form

Purified

Applications

Immunocytochemistry, Western Blot

Clone

RM114

Gene Accession No.

P04406

Host Species

Rabbit

Purification Method

Protein A Purfied

Regulatory Status

RUO

Primary or Secondary

Primary

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

Isotype

IgG

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Description

  • Specifically detects GAPDH (CT) clone: RM114 in Human samples, and it is validated for Immunocytochemistry, Western Blotting Glyceraldehyde 3-phosphate dehydrogenase (GAPDH) is an ubiquitous glycolytic enzyme present in moderately high levels in almost all tissues
  • As a 'house-keeping' enzyme, it catalyzes the synthesis of 1,3-biphosphoglycerate, a 'high energy' intermediate used for the synthesis of ATP
  • Besides its cytoplasmic action in metabolism it is also involved in the initial stages of apoptosis or oxidative stress response where GAPDH is translocated to the nucleus
  • Such actions may reflect the role of GAPDH in DNA repair or as one nuclear carrier for apoptotic molecules
  • GAPDH has also been found to bind specifically to proteins implicated in the pathogenesis of a variety of neurodegenerative disorders including the beta-amyloid precursor protein and the huntingtin protein where decreased function of GAPDH is associated with Alzheimer's and Huntington's disease fibroblasts
  • GAPDH has also been identified as a potential target for nitric oxide (NO)-mediated cellular toxicity
  • The complete and functional enzyme is a tetramer with each of four identical subunits occupying the vertex of a tetrahedron
  • Binding domains also include one principally interacting with NAD+ and another interacting with glyceraldehyde 3-phosphate (GAP).

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Show Difference

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MilliporeSigma™

MABS819MI

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Antigen:
GAPDH (CT)

Classification:
Monoclonal

Formulation:
Rabbit monoclonal in PBS with 1% BSA and 0.09% sodium azide.

Gene Symbols:
GAPDH; GAPD; CDABP0047

Immunogen:
A peptide corresponding to the C-terminus of GAPDH.

Quantity:
100 μL

Research Discipline:
Signaling

Target Species:
Human

Form:
Purified

Applications:
Immunocytochemistry, Western Blot

Clone:
RM114

Gene Accession No.:
P04406

Host Species:
Rabbit

Purification Method:
Protein A Purfied

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

Isotype:
IgG

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MABS826MI

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Antigen:
Rsk1

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Symbols:
__

Immunogen:
KLH-conjugated linear peptide corresponding to a sequence from the linker region between the two human Rsk1 kinase domains.

Quantity:
100 μg

Research Discipline:
Signaling

Target Species:
Rat

Form:
Purified

Applications:
Western Blot

Clone:
3G5.1

Gene Accession No.:
Q15418

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

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Antigen:
phospho-EGFR (Tyr1173)

Classification:
Monoclonal

Formulation:
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Gene Symbols:
EGFR,ERBB,ERBB1,HER1

Immunogen:
KLH-conjugated linear peptide corresponding to 13 amino acids surrrounding Tyrosine 1173 of human epidermal growth factor receptor.

Quantity:
100 μL

Research Discipline:
Signaling

Target Species:
Human

Form:
Purified

Applications:
Immunocytochemistry, Western Blot

Clone:
3E7.2

Gene Accession No.:
__

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG2b κ

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Antigen:
phospho-p70 S6 Kinase (Thr389)

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
RPS6KB1, STK14A

Immunogen:
KLH-conjugated linear peptide corresponding to mouse p70 S6 Kinase phosphorylated at (Thr389).

Quantity:
100 μg

Research Discipline:
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Target Species:
Human, Mouse

Form:
Purified

Applications:
Immunocytochemistry, Western Blot

Clone:
10G7.1

Gene Accession No.:
NP_003152

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Content And Storage:
2-8°C for one year

Isotype:
IgG2a κ