MABS83025UG
Acetyl CoA Carboxylase 1, Mouse anti-Mouse, Human, Clone: 7H4.2, Millipore Sigma™
Manufacturer: MilliporeSigma
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS83025UG-Each-of-1 | In Stock | ₹ 16,456.61 |
MABS83025UG - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,456.61
GST (18%): ₹ 2,962.19
Total Price: ₹ 19,418.80
Antigen
Acetyl CoA Carboxylase 1
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols
ACACA;ACAC;ACC1;ACCA
Immunogen
GST/His-tagged recombinant fragment corresponding to 86 amino acids from the C-terminal end of human Acetyl-CoA carboxylase 1.
Quantity
25 μg
Research Discipline
Signaling
Test Specificity
Clone 7H4.2 detects acetyl-CoA carboxylase 1 in human. It targets an epitope within 86 amino acids from the C-terminal end.
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Isotype
IgG2b
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
7H4.2
Dilution
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Acetyl CoA Carboxylase 1 in human tonsil, human testis, and human cervical cancer tissue. Western Blotting Analysis: 0.5μg/mL from a representative lot detected Acetyl CoA Carboxylase 1 in 10μg of NIH/3T3 cell lyate.
Gene Alias
ACC1;ACC-alpha
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Mouse, Human
Form
Purified
Description
- Anti-Acetyl CoA Carboxylase 1 Antibody, clone 7H4.2, Cat
- No
- MABS830, is a mouse monoclonal antibody that targets Acetyl CoA Carboxylase 1 and has been tested for use in Immunohistochemistry (Paraffin) and Western Blotting
- Acetyl-CoA carboxylase 1 (UniProt: Q13085; also known as ACC1, ACC-alpha) is encoded by the ACACA (also known as ACAC, ACC1, ACCA) gene (Gene ID: 31) in human
- It catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids
- ACC1 is a multi-subunit, biotin-dependent enzyme that catalyzes carboxylation of acetyl-CoA to produce malonyl-CoA through its two catalytic activities, biotin carboxylase (BC) and carboxyltransferase (CT)
- The activity of ACC can be controlled at the transcriptional level as well as by small molecule modulators and covalent modification
- Two isoforms fof ACC have been reported, alpha and beta that are encoded by two different genes
- ACC-alpha is highly enriched in lipogenic tissues
- ACC1 levels are regulated under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA
- ACC1 activity is inhibited upon phosphorylation, which occurs when glucagon or epinephrine binds to the receptors or when the energy status of the cell is low, leading to the activation of the AMP-activated protein kinase
- The presence of fatty acids inhibits the activities of ACC1
- ACC is considered as an important target in the design of new anti-obesity drugs.
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Antigen: Acetyl CoA Carboxylase 1
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: ACACA;ACAC;ACC1;ACCA
Immunogen: GST/His-tagged recombinant fragment corresponding to 86 amino acids from the C-terminal end of human Acetyl-CoA carboxylase 1.
Quantity: 25 μg
Research Discipline: Signaling
Test Specificity: Clone 7H4.2 detects acetyl-CoA carboxylase 1 in human. It targets an epitope within 86 amino acids from the C-terminal end.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2b
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 7H4.2
Dilution: Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Acetyl CoA Carboxylase 1 in human tonsil, human testis, and human cervical cancer tissue. Western Blotting Analysis: 0.5μg/mL from a representative lot detected Acetyl CoA Carboxylase 1 in 10μg of NIH/3T3 cell lyate.
Gene Alias: ACC1;ACC-alpha
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse, Human
Form: Purified
Antigen:
Acetyl CoA Carboxylase 1
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
ACACA;ACAC;ACC1;ACCA
Immunogen:
GST/His-tagged recombinant fragment corresponding to 86 amino acids from the C-terminal end of human Acetyl-CoA carboxylase 1.
Quantity:
25 μg
Research Discipline:
Signaling
Test Specificity:
Clone 7H4.2 detects acetyl-CoA carboxylase 1 in human. It targets an epitope within 86 amino acids from the C-terminal end.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2b
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
7H4.2
Dilution:
Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Acetyl CoA Carboxylase 1 in human tonsil, human testis, and human cervical cancer tissue. Western Blotting Analysis: 0.5μg/mL from a representative lot detected Acetyl CoA Carboxylase 1 in 10μg of NIH/3T3 cell lyate.
Gene Alias:
ACC1;ACC-alpha
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse, Human
Form:
Purified
Antigen: PI3 Kinase
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: PIK3R1;GRB1
Immunogen: GST/His-tagged recombinant fragment corresponding to 77 amino acids from the N-terminal region of the p85 regulatory subunit of human PI 3-kinase alpha.
Quantity: 25 μg
Research Discipline: Signaling
Test Specificity: Clone 1D5.1 detects p85 subunit of human and murine PI-3 kinase alpha. It targets an epitope within 77 amino acids from the N-terminal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2b κ
Applications: Western Blot
Clone: 1D5.1
Dilution: Western Blotting Analysis: 0.5μg/mL from a representative lot detected PI3 Kinase, p85, N-SH3 in 10μg of human cerebral cortex tissue lysate.
Gene Alias: Phosphatidylinositol 3-kinase regulatory subunit alpha;Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha;PI3-kinase regulatory subunit alpha;PtdIns-3-kinase regulatory subunit p85-alpha;PI3-kinase subunit p85-alpha;PI3K regulatory subunit alpha;PtdIns-3-kinase regulatory subunit alpha
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse, Human
Form: Purified
Antigen:
PI3 Kinase
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
PIK3R1;GRB1
Immunogen:
GST/His-tagged recombinant fragment corresponding to 77 amino acids from the N-terminal region of the p85 regulatory subunit of human PI 3-kinase alpha.
Quantity:
25 μg
Research Discipline:
Signaling
Test Specificity:
Clone 1D5.1 detects p85 subunit of human and murine PI-3 kinase alpha. It targets an epitope within 77 amino acids from the N-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
1D5.1
Dilution:
Western Blotting Analysis: 0.5μg/mL from a representative lot detected PI3 Kinase, p85, N-SH3 in 10μg of human cerebral cortex tissue lysate.
Gene Alias:
Phosphatidylinositol 3-kinase regulatory subunit alpha;Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha;PI3-kinase regulatory subunit alpha;PtdIns-3-kinase regulatory subunit p85-alpha;PI3-kinase subunit p85-alpha;PI3K regulatory subunit alpha;PtdIns-3-kinase regulatory subunit alpha
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse, Human
Form:
Purified
Antigen: PI3 Kinase
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: __
Gene Symbols: PIK3R1,GRB1
Immunogen: GST/His-tagged recombinant fragment corresponding to 77 amino acids from the N-terminal region of the p85 regulatory subunit of human PI 3-kinase alpha.
Quantity: 100 μg
Research Discipline: Signaling
Test Specificity: Clone 1D5.1 detects p85 subunit of human and murine PI-3 kinase alpha. It targets an epitope within 77 amino acids from the N-terminal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2b κ
Applications: Western Blot
Clone: 1D5.1
Dilution: __
Gene Alias: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse, Human
Form: Purified
Antigen:
PI3 Kinase
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
__
Gene Symbols:
PIK3R1,GRB1
Immunogen:
GST/His-tagged recombinant fragment corresponding to 77 amino acids from the N-terminal region of the p85 regulatory subunit of human PI 3-kinase alpha.
Quantity:
100 μg
Research Discipline:
Signaling
Test Specificity:
Clone 1D5.1 detects p85 subunit of human and murine PI-3 kinase alpha. It targets an epitope within 77 amino acids from the N-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
1D5.1
Dilution:
__
Gene Alias:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse, Human
Form:
Purified
Antigen: __
Classification: __
Conjugate: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Test Specificity: __
Content And Storage: __
Isotype: __
Applications: __
Clone: __
Dilution: __
Gene Alias: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Target Species: __
Form: __
Antigen:
__
Classification:
__
Conjugate:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Test Specificity:
__
Content And Storage:
__
Isotype:
__
Applications:
__
Clone:
__
Dilution:
__
Gene Alias:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Target Species:
__
Form:
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