Manufacturer: Novus Biologicals
Pack Size | SKU | Availability | Price |
---|---|---|---|
Each of 1 | NB005717-Each-of-1 | In Stock | ₹ 55,271.76 |
NB005717 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Plasma Cell
Monoclonal
Alexa Fluor 594
50mM Sodium Borate with 0.05% Sodium Azide
Mouse
Protein A or G purified
RUO
Primary
Human, Rat (Negative)
IgG2a κ
Immunohistochemistry, Immunohistochemistry (Paraffin)
LIV3G11 (7B18)
Immunohistochemistry, Immunohistochemistry-Paraffin
Plasma
Pancreatic cancer related serum mucin was used as the immunogen for the Plasma Cell antibody.
0.1 mL
Immunology
It recognizes an intra-cytoplasmic antigen, which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4+ lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm; their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This monoclonal antibody superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Note that this monoclonal antibody is not suitable for staining frozen tissues.
Store at 4°C in the dark.