NB006096
Siglec-3/CD33 Antibody (WM53), FITC, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB006096-Each-of-1 | In Stock | ₹ 55,271.76 |
NB006096 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
Siglec-3/CD33
Classification
Monoclonal
Conjugate
FITC
Formulation
PBS with 0.05% Sodium Azide
Gene Symbols
CD33
Immunogen
Human AML cells
Quantity
0.1 mL
Research Discipline
Immunology
Test Specificity
Recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV; WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immuno-receptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
Content And Storage
Store at 4°C in the dark.
Applications
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Clone
WM53
Dilution
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Gene Alias
CD33 antigen, CD33 antigen (gp67), CD33 molecule, FLJ00391, myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3, SIGLEC-3, SIGLEC3gp67
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Isotype
IgG1 κ
Related Products
Description
- Siglec-3/CD33 Monoclonal specifically detects Siglec-3/CD33 in Human samples
- It is validated for Flow Cytometry, Immunocytochemistry/Immunofluorescence.
Compare Similar Items
Show Difference
Antigen: Siglec-3/CD33
Classification: Monoclonal
Conjugate: FITC
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: CD33
Immunogen: Human AML cells
Quantity: 0.1 mL
Research Discipline: Immunology
Test Specificity: Recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV; WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immuno-receptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Clone: WM53
Dilution: Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Gene Alias: CD33 antigen, CD33 antigen (gp67), CD33 molecule, FLJ00391, myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3, SIGLEC-3, SIGLEC3gp67
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG1 κ
Antigen:
Siglec-3/CD33
Classification:
Monoclonal
Conjugate:
FITC
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
CD33
Immunogen:
Human AML cells
Quantity:
0.1 mL
Research Discipline:
Immunology
Test Specificity:
Recognizes a 67kDa glycoprotein, which is identified as CD33 (HLDA IV; WS Code M-505). CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immuno-receptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells.
Content And Storage:
Store at 4°C in the dark.
Applications:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Clone:
WM53
Dilution:
Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Frozen
Gene Alias:
CD33 antigen, CD33 antigen (gp67), CD33 molecule, FLJ00391, myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, Sialic acid-binding Ig-like lectin 3, SIGLEC-3, SIGLEC3gp67
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG1 κ
Antigen: alpha-Methylacyl-CoA Racemase/AMACR
Classification: Polyclonal
Conjugate: Alexa Fluor 350
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: AMACR
Immunogen: A synthetic peptide from human AMACR protein
Quantity: 0.1 mL
Research Discipline: Lipid and Metabolism, Prostate Cancer, Signal Transduction
Test Specificity: This antibody recognizes a protein of 54kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: __
Dilution: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias: 2-methylacyl-CoA racemase, alpha-methylacyl-CoA racemase, CBAS4, EC 5.1.99.4, RACE, RM
Host Species: Rabbit
Purification Method: Protein A purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG
Antigen:
alpha-Methylacyl-CoA Racemase/AMACR
Classification:
Polyclonal
Conjugate:
Alexa Fluor 350
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
AMACR
Immunogen:
A synthetic peptide from human AMACR protein
Quantity:
0.1 mL
Research Discipline:
Lipid and Metabolism, Prostate Cancer, Signal Transduction
Test Specificity:
This antibody recognizes a protein of 54kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
__
Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
2-methylacyl-CoA racemase, alpha-methylacyl-CoA racemase, CBAS4, EC 5.1.99.4, RACE, RM
Host Species:
Rabbit
Purification Method:
Protein A purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG
Antigen: alpha-Methylacyl-CoA Racemase/AMACR
Classification: Polyclonal
Conjugate: DyLight 594
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: AMACR
Immunogen: A synthetic peptide from human AMACR protein
Quantity: 0.1 mL
Research Discipline: Lipid and Metabolism, Prostate Cancer, Signal Transduction
Test Specificity: This antibody recognizes a protein of 54kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: __
Dilution: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias: 2-methylacyl-CoA racemase, alpha-methylacyl-CoA racemase, CBAS4, EC 5.1.99.4, RACE, RM
Host Species: Rabbit
Purification Method: Protein A purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG
Antigen:
alpha-Methylacyl-CoA Racemase/AMACR
Classification:
Polyclonal
Conjugate:
DyLight 594
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
AMACR
Immunogen:
A synthetic peptide from human AMACR protein
Quantity:
0.1 mL
Research Discipline:
Lipid and Metabolism, Prostate Cancer, Signal Transduction
Test Specificity:
This antibody recognizes a protein of 54kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and over expressed in prostate carcinoma.
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
__
Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
2-methylacyl-CoA racemase, alpha-methylacyl-CoA racemase, CBAS4, EC 5.1.99.4, RACE, RM
Host Species:
Rabbit
Purification Method:
Protein A purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG
Antigen: alpha-Methylacyl-CoA Racemase/AMACR
Classification: Polyclonal
Conjugate: Janelia Fluor 646
Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols: AMACR
Immunogen: A synthetic peptide from human AMACR protein
Quantity: 0.1 mL
Research Discipline: Lipid and Metabolism, Prostate Cancer, Signal Transduction
Test Specificity: This antibody recognizes a protein of 54kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies ha
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: __
Dilution: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias: 2-methylacyl-CoA racemase, alpha-methylacyl-CoA racemase, CBAS4, EC 5.1.99.4, RACE, RM
Host Species: Rabbit
Purification Method: Protein A purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Isotype: IgG
Antigen:
alpha-Methylacyl-CoA Racemase/AMACR
Classification:
Polyclonal
Conjugate:
Janelia Fluor 646
Formulation:
50mM Sodium Borate with 0.05% Sodium Azide
Gene Symbols:
AMACR
Immunogen:
A synthetic peptide from human AMACR protein
Quantity:
0.1 mL
Research Discipline:
Lipid and Metabolism, Prostate Cancer, Signal Transduction
Test Specificity:
This antibody recognizes a protein of 54kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies ha
Content And Storage:
Store at 4°C in the dark.
Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
__
Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
2-methylacyl-CoA racemase, alpha-methylacyl-CoA racemase, CBAS4, EC 5.1.99.4, RACE, RM
Host Species:
Rabbit
Purification Method:
Protein A purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Isotype:
IgG