NB017566
Fc gamma RIIIA/CD16a Antibody (DJ130c) - BSA Free, Novus Biologicals™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NB017566-Each-of-1 | In Stock | ₹ 17,668.14 |
NB017566 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,668.14
GST (18%): ₹ 3,180.265
Total Price: ₹ 20,848.405
Antigen
Fc gamma RIIIA/CD16a
Classification
Monoclonal
Concentration
1.0 mg/mL
Dilution
Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Accession No.
P08637
Gene Symbols
FCGR3A
Immunogen
CD34 antigen
Quantity
0.025 mg
Research Discipline
Innate Immunity
Gene ID (Entrez)
2214
Target Species
Human
Form
Purified
Applications
Immunohistochemistry (Frozen), Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone
DJ130c
Conjugate
Unconjugated
Formulation
Phosphate buffered saline with 0.09% Sodium Azide
Gene Alias
CD16a, CD16a antigen, CD16FCRIIIA, Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor III-A, FCG3, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIIIa, Fc-gamma RIII-alpha, FCGR3, FCGRIII, FCR-10, FcRIII, FcRIIIa, IGFR3FcgammaRIIIA, immunoglobulin G Fc receptor III, low affinity III, receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
NB100-64346 recognizes human CD16, a 50-65kD cell surface molecule, which is the low affinity receptor for IgG (FcR III). CD16 exists as a transmembranous form (Fc gammaRIIIA, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B). CD16A is expressed by NK cells, some T cells, and macrophages, whereas CD16B is primarily expressed by granulocytes. In addition, CD16B exists as two allelic variants NA1 and NA2. DJ130c recognizes all polymorphonuclear cells irrespective on their NA phenotype. Studies show that the DJ130c antibody recognizes an epitope in the first membrane-distal domain of CD16 and recognizes both CD16A and CD16B.
Content And Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype
IgG1
Related Products
Description
- Fc gamma RIIIA/CD16a Monoclonal specifically detects Fc gamma RIIIA/CD16a in Human samples
- It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.
Compare Similar Items
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Antigen: Fc gamma RIIIA/CD16a
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Accession No.: P08637
Gene Symbols: FCGR3A
Immunogen: CD34 antigen
Quantity: 0.025 mg
Research Discipline: Innate Immunity
Gene ID (Entrez): 2214
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Frozen), Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: DJ130c
Conjugate: Unconjugated
Formulation: Phosphate buffered saline with 0.09% Sodium Azide
Gene Alias: CD16a, CD16a antigen, CD16FCRIIIA, Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor III-A, FCG3, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIIIa, Fc-gamma RIII-alpha, FCGR3, FCGRIII, FCR-10, FcRIII, FcRIIIa, IGFR3FcgammaRIIIA, immunoglobulin G Fc receptor III, low affinity III, receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: NB100-64346 recognizes human CD16, a 50-65kD cell surface molecule, which is the low affinity receptor for IgG (FcR III). CD16 exists as a transmembranous form (Fc gammaRIIIA, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B). CD16A is expressed by NK cells, some T cells, and macrophages, whereas CD16B is primarily expressed by granulocytes. In addition, CD16B exists as two allelic variants NA1 and NA2. DJ130c recognizes all polymorphonuclear cells irrespective on their NA phenotype. Studies show that the DJ130c antibody recognizes an epitope in the first membrane-distal domain of CD16 and recognizes both CD16A and CD16B.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1
Antigen:
Fc gamma RIIIA/CD16a
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Dilution:
Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Gene Accession No.:
P08637
Gene Symbols:
FCGR3A
Immunogen:
CD34 antigen
Quantity:
0.025 mg
Research Discipline:
Innate Immunity
Gene ID (Entrez):
2214
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Frozen), Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
DJ130c
Conjugate:
Unconjugated
Formulation:
Phosphate buffered saline with 0.09% Sodium Azide
Gene Alias:
CD16a, CD16a antigen, CD16FCRIIIA, Fc fragment of IgG, low affinity IIIa, receptor (CD16a), Fc fragment of IgG, low affinity IIIa, receptor for (CD16), Fc gamma receptor III-A, FCG3, Fc-gamma receptor III-2 (CD 16), Fc-gamma receptor IIIb (CD16), Fc-gamma RIII, Fc-gamma RIIIa, Fc-gamma RIII-alpha, FCGR3, FCGRIII, FCR-10, FcRIII, FcRIIIa, IGFR3FcgammaRIIIA, immunoglobulin G Fc receptor III, low affinity III, receptor for (CD16), low affinity immunoglobulin gamma Fc region receptor III-A, neutrophil-specific antigen NA
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB100-64346 recognizes human CD16, a 50-65kD cell surface molecule, which is the low affinity receptor for IgG (FcR III). CD16 exists as a transmembranous form (Fc gammaRIIIA, or CD16A) and a glycosyl phosphatidylinositol (GPI) anchored form (Fc gammaRIIIB, or CD16B). CD16A is expressed by NK cells, some T cells, and macrophages, whereas CD16B is primarily expressed by granulocytes. In addition, CD16B exists as two allelic variants NA1 and NA2. DJ130c recognizes all polymorphonuclear cells irrespective on their NA phenotype. Studies show that the DJ130c antibody recognizes an epitope in the first membrane-distal domain of CD16 and recognizes both CD16A and CD16B.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1
Antigen: HLA DQ/DR/DP
Classification: Monoclonal
Concentration: 1.0 mg/ml
Dilution: Flow Cytometry 1:50-1:200, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Functional
Gene Accession No.: __
Gene Symbols: HLA-DQA1
Immunogen: Human HLA Class II (DP, DQ, DR)
Quantity: 0.025 mg
Research Discipline: Adaptive Immunity, Asthma, Immunology
Gene ID (Entrez): 3117
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin), Flow Cytometry, Immunohistochemistry, Functional Assay
Clone: WR18
Conjugate: Unconjugated
Formulation: PBS with 0.09% Sodium Azide
Gene Alias: CD, CELIAC1DQ alpha 1 chain, DC-1 alpha chain, DQ-A1, FLJ27088, FLJ27328, GSE, HLA class II histocompatibility antigen, DQ(W3) alpha chain, HLA-DCA, HLA-DQA, leucocyte antigen DQA1, leukocyte antigen alpha chain, major histocompatibility complex, class II, DQ alpha 1, MGC149527, MHC class II antigen, MHC class II DQA1, MHC class II HLA-D alpha glycoprotein, MHC class II HLA-DQ-alpha-1, MHC class II surface glycoprotein, MHC HLA-DQ alpha
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes HLA Class II beta chains of human major histocompatability antigen, Mw 28 kD. It reacts with a monomorphic determinant common to each beta chain type. The antigen is expressed by human B lymphocytes, monocytes and activated T lymphocytes.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG2a
Antigen:
HLA DQ/DR/DP
Classification:
Monoclonal
Concentration:
1.0 mg/ml
Dilution:
Flow Cytometry 1:50-1:200, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Functional
Gene Accession No.:
__
Gene Symbols:
HLA-DQA1
Immunogen:
Human HLA Class II (DP, DQ, DR)
Quantity:
0.025 mg
Research Discipline:
Adaptive Immunity, Asthma, Immunology
Gene ID (Entrez):
3117
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin), Flow Cytometry, Immunohistochemistry, Functional Assay
Clone:
WR18
Conjugate:
Unconjugated
Formulation:
PBS with 0.09% Sodium Azide
Gene Alias:
CD, CELIAC1DQ alpha 1 chain, DC-1 alpha chain, DQ-A1, FLJ27088, FLJ27328, GSE, HLA class II histocompatibility antigen, DQ(W3) alpha chain, HLA-DCA, HLA-DQA, leucocyte antigen DQA1, leukocyte antigen alpha chain, major histocompatibility complex, class II, DQ alpha 1, MGC149527, MHC class II antigen, MHC class II DQA1, MHC class II HLA-D alpha glycoprotein, MHC class II HLA-DQ-alpha-1, MHC class II surface glycoprotein, MHC HLA-DQ alpha
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes HLA Class II beta chains of human major histocompatability antigen, Mw 28 kD. It reacts with a monomorphic determinant common to each beta chain type. The antigen is expressed by human B lymphocytes, monocytes and activated T lymphocytes.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG2a
Antigen: SerpinB9
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:100, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:50, Immunohistochemistry-Frozen 1:10-1:500
Gene Accession No.: P50453
Gene Symbols: SERPINB9
Immunogen: Recombinant PI-9 produced in P. pastoris.
Quantity: 0.025 mg
Research Discipline: Apoptosis, Immunology
Gene ID (Entrez): 5272
Target Species: Mouse (Negative), Porcine (Negative), Human
Form: Purified
Applications: Immunohistochemistry (Frozen), Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Flow Cytometry
Clone: 7D8
Conjugate: Unconjugated
Formulation: PBS with 0.05% Sodium Azide
Gene Alias: CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kDa under reducing conditions. Clone 7D8 is suitable for use in indirect Immunofluorescence (2).
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1
Antigen:
SerpinB9
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Dilution:
Western Blot 1:100-1:2000, Flow Cytometry 1:10-1:100, Immunohistochemistry 1:10-1:500, Immunohistochemistry-Paraffin 1:50, Immunohistochemistry-Frozen 1:10-1:500
Gene Accession No.:
P50453
Gene Symbols:
SERPINB9
Immunogen:
Recombinant PI-9 produced in P. pastoris.
Quantity:
0.025 mg
Research Discipline:
Apoptosis, Immunology
Gene ID (Entrez):
5272
Target Species:
Mouse (Negative), Porcine (Negative), Human
Form:
Purified
Applications:
Immunohistochemistry (Frozen), Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin), Flow Cytometry
Clone:
7D8
Conjugate:
Unconjugated
Formulation:
PBS with 0.05% Sodium Azide
Gene Alias:
CAP-3, CAP3PI-9, Cytoplasmic antiproteinase 3, Peptidase inhibitor 9, PI9protease inhibitor 9 (ovalbumin type), serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 9, serpin B9, serpin peptidase inhibitor, clade B (ovalbumin), member 9, serpin peptidase inhibitor, clade B, member 9
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB100-64359 is specific for human PI-9 (proteinase inhibitor 9), also known as SerpinB9, a 42kDa intracellular nucleocytoplasmic serpin expressed in cytotoxic lymphocytes (CTLs), natural killer (NK) cells, monocyte-derived dendritic cells (DCs), and to a lesser extent in B cells and myeloid cells. Granzyme B (grB) is a serine protease highly expressed by CTLs and NK cells, which is endocytosed by virus-infected and malignant target cells. The subsequent release of grB from the endocytic vesicles into the cytoplasm of the target cells, triggers grB-mediated apoptosis, through cleavage of various cytoplasmic or nuclear proteins. PI-9, up-regulated in response to grB production and degranulation, has been identified as a potent inhibitor of Granzyme B-mediated apoptosis, providing a vital self-protection mechanism against the premature apoptosis of CTLs and NK cells by grB, which may escape into the cytoplasm of the effector cells themselves. Clone 7D8 detects a band of approximately 42kDa under reducing conditions. Clone 7D8 is suitable for use in indirect Immunofluorescence (2).
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1
Antigen: CD19
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Flow Cytometry 1:50-1:200, Immunoprecipitation 1:10-1:500
Gene Accession No.: P15391
Gene Symbols: CD19
Immunogen: Human EB-4 Burkitt lymphoma cell line.
Quantity: 0.025 mg
Research Discipline: Cytokine Research, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Signal Transduction, Stem Cell Markers
Gene ID (Entrez): 930
Target Species: Human
Form: Purified
Applications: Immunoprecipitation, Flow Cytometry
Clone: Bu12
Conjugate: Unconjugated
Formulation: Phosphate buffered saline with 0.09% Sodium Azide
Gene Alias: B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19 antigen, CD19 molecule, CVID3, Differentiation antigen CD19, MGC12802, T-cell surface antigen Leu-12
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: NB100-64360 recognizes human CD19, a 95kD cell surface glycoprotein, which is expressed on cells of the B cell lineage and follicular dendritic cells but absent on plasma cells. CD19 is an important signal transduction molecule which is involved in the regulation of B lymphocyte development, activation and differentiation.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1
Antigen:
CD19
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Dilution:
Flow Cytometry 1:50-1:200, Immunoprecipitation 1:10-1:500
Gene Accession No.:
P15391
Gene Symbols:
CD19
Immunogen:
Human EB-4 Burkitt lymphoma cell line.
Quantity:
0.025 mg
Research Discipline:
Cytokine Research, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Signal Transduction, Stem Cell Markers
Gene ID (Entrez):
930
Target Species:
Human
Form:
Purified
Applications:
Immunoprecipitation, Flow Cytometry
Clone:
Bu12
Conjugate:
Unconjugated
Formulation:
Phosphate buffered saline with 0.09% Sodium Azide
Gene Alias:
B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19 antigen, CD19 molecule, CVID3, Differentiation antigen CD19, MGC12802, T-cell surface antigen Leu-12
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
NB100-64360 recognizes human CD19, a 95kD cell surface glycoprotein, which is expressed on cells of the B cell lineage and follicular dendritic cells but absent on plasma cells. CD19 is an important signal transduction molecule which is involved in the regulation of B lymphocyte development, activation and differentiation.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1