NBP229407

PMEL17/SILV Antibody (NKI-beteb), Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP229407-Each-of-1 In Stock ₹ 44,833.44

NBP229407 - Each of 1

₹ 44,833.44

In Stock

Quantity

1

Base Price: ₹ 44,833.44

GST (18%): ₹ 8,070.019

Total Price: ₹ 52,903.459

Antigen

PMEL17/SILV

Classification

Monoclonal

Concentration

0.2 mg/ml

Dilution

Immunohistochemistry, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array, Flow (Intracellular)

Gene Alias

D12S53EP1, gp100, ME20, ME20-M, melanocyte protein mel 17, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, melanosomal matrix protein17, PMEL17P100, premelanosome proteinME20M, SI, SIL, silver (mouse homolog) like, silver homolog (mouse), Silver locus protein homolog, silver, mouse, homolog of, SILVPmel17

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Gene ID (Entrez)

6490

Target Species

Human, Equine

Form

Purified

Applications

Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array, Flow Cytometry, Immunohistochemistry (Frozen)

Clone

NKI-beteb

Conjugate

Unconjugated

Gene Accession No.

P40967

Gene Symbols

PMEL

Immunogen

Lymph node pigmented melanoma metastases extract was used as the immunogen for the gp100 NKI-beteb antibody

Quantity

0.1 mg

Primary or Secondary

Primary

Test Specificity

By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This monoclonal antibody reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

Content And Storage

Store at 4C.

Isotype

IgG2b κ

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Description

  • PMEL17/SILV Monoclonal specifically detects PMEL17/SILV in Human, Equine samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array, Flow (Intracellular).

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Novus Biologicals

NBP229407

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Antigen:
PMEL17/SILV

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin 1-2 ug/ml, Protein Array, Flow (Intracellular)

Gene Alias:
D12S53EP1, gp100, ME20, ME20-M, melanocyte protein mel 17, Melanocyte protein Pmel 17, Melanocytes lineage-specific antigen GP100, Melanoma-associated ME20 antigen, melanosomal matrix protein17, PMEL17P100, premelanosome proteinME20M, SI, SIL, silver (mouse homolog) like, silver homolog (mouse), Silver locus protein homolog, silver, mouse, homolog of, SILVPmel17

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
6490

Target Species:
Human, Equine

Form:
Purified

Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array, Flow Cytometry, Immunohistochemistry (Frozen)

Clone:
NKI-beteb

Conjugate:
Unconjugated

Gene Accession No.:
P40967

Gene Symbols:
PMEL

Immunogen:
Lymph node pigmented melanoma metastases extract was used as the immunogen for the gp100 NKI-beteb antibody

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
By immunohistochemistry, it specifically recognizes a protein in melanocytes and melanomas. This monoclonal antibody reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. This Mab labels formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

Content And Storage:
Store at 4C.

Isotype:
IgG2b κ

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NBP229409

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Antigen:
Cytokeratin 18

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Western Blot 1-3 μg/mL, Simple Western 10 μg/mL, Flow Cytometry 0.5-1 μg/million cells, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1-2 μg/mL, Immunoprecipitation 1-2 μg/500 μg protein lysate, Immunohistochemistry-Paraffin 0.5-1.0 μg/mL

Gene Alias:
Cell proliferation-inducing gene 46 protein, cell proliferation-inducing protein 46, CK-18, CYK18, cytokeratin 18, cytokeratin-18, K18, keratin 18, keratin, type I cytoskeletal 18, keratin-18

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
3875

Target Species:
Human, Bovine (Negative), Canine (Negative), Hamster (Negative), Mouse (Negative), Porcine (Negative), Rat (Negative)

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
DA7

Conjugate:
Unconjugated

Gene Accession No.:
P05783

Gene Symbols:
KRT18

Immunogen:
Human breast cancer PMC 42 cells were used as immunogen to generate the Cytokeratin 18 (CK18) antibody.

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

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NBP229411

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Antigen:
Cytokeratin, LMW

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Western Blot 0.5-1 μg/mL, Flow Cytometry 0.5-1 μg/million cells, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1-2 μg/mL, Immunohistochemistry-Paraffin 0.5-1 μg/mL, Immunohistochemistry-Frozen 0.5-1 μg/mL

Gene Alias:
Cytokeratin LMW, cytokeratin-1B, keratin 77, keratin, type II cytoskeletal 1b, KRT77, type-II keratin Kb39

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
374454

Target Species:
Human, Mouse, Rat, Bovine, Canine, Chicken, Other, Primate, Rabbit

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
AE-1

Conjugate:
Unconjugated

Gene Accession No.:
P04264

Gene Symbols:
KRT77

Immunogen:
Human epidermal keratin (Uniprot: Q7Z794)

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody recognizes the 56.5kDa (CK10); 50kDa (CK14); 50kDa (CK15); 48kDa (CK16); 40kDa (CK19) keratins of the acidic (Type I or LMW) subfamily. Twenty human keratins are resolved with two-dimensional gel electrophoresis into acidic (pI, 48, 46, 45, and 40kDa. monoclonal antibody AE3 recognizes the 65-67, 64, 59, 58, 56, and 52kDa keratins of basic subfamily. Many studies have shown the usefulness of keratins as markers in cancer research and tumor diagnosis. AE1/AE3 is a broad spectrum anti pan-keratin antibody cocktail, which differentiates epithelial tumors from non-epithelial tumors e.g. squamous vs. adenocarcinoma of the lung, liver carcinoma, breast cancer, and esophageal cancer.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

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NBP22941549

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Antigen:
TCRalpha/beta

Classification:
Monoclonal

Concentration:
__

Dilution:
Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen

Gene Alias:
C), D, FLJ22602, J, MGC117436, MGC22624, MGC23964, MGC71411, T cell receptor alpha locus, T-cell antigen receptor, alpha polypeptide, T-cell receptor, alpha (V, TCRA, TCRD, TRA

Host Species:
Mouse

Purification Method:
Protein A purified

Regulatory Status:
__

Gene ID (Entrez):
6955

Target Species:
Primate, Rat

Form:
Purified

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)

Clone:
R73

Conjugate:
Janelia Fluor 549

Gene Accession No.:
__

Gene Symbols:
TRA

Immunogen:
Rat T blasts and erythrocytes

Quantity:
0.1 mL

Primary or Secondary:
Primary

Test Specificity:
The mouse monoclonal R73 recognizes TCR alpha/beta, the dominant subtype of T cell receptor expressed in peripheral blood.

Content And Storage:
Store at 4°C in the dark.

Isotype:
IgG1 κ