NBP229432

NKX2.2 Antibody (NX2/294), Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP229432-Each-of-1 In Stock ₹ 45,004.56

NBP229432 - Each of 1

₹ 45,004.56

In Stock

Quantity

1

Base Price: ₹ 45,004.56

GST (18%): ₹ 8,100.821

Total Price: ₹ 53,105.381

Antigen

NKX2.2

Classification

Monoclonal

Concentration

0.2 mg/mL

Dilution

Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml

Gene Alias

Homeobox protein NK-2 homolog B, NK-2 (Drosophila) homolog B, NK2 homeobox 2, NK2 transcription factor related, locus 2, NK2 transcription factor related, locus 2 (Drosophila), NK2 transcription factor-like protein B, Nkx2.2, NKX2.2homeobox protein Nkx-2.2, NKX2BNK-2 homolog B

Host Species

Mouse

Purification Method

Protein A or G purified

Regulatory Status

RUO

Gene ID (Entrez)

4821

Target Species

Human, Mouse, Rat, Chicken

Form

Purified

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone

NX2/294

Conjugate

Unconjugated

Gene Accession No.

O95096

Gene Symbols

NKX2-2

Immunogen

Human full-length recombinant NKX2.2 protein (Uniprot: O95096)

Quantity

0.1 mg

Primary or Secondary

Primary

Test Specificity

Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

Content And Storage

Store at 4C.

Isotype

IgG2b κ

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Description

  • NKX2.2 Monoclonal specifically detects NKX2.2 in Human, Mouse, Rat, Chicken samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NBP229432

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Antigen:
NKX2.2

Classification:
Monoclonal

Concentration:
0.2 mg/mL

Dilution:
Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml

Gene Alias:
Homeobox protein NK-2 homolog B, NK-2 (Drosophila) homolog B, NK2 homeobox 2, NK2 transcription factor related, locus 2, NK2 transcription factor related, locus 2 (Drosophila), NK2 transcription factor-like protein B, Nkx2.2, NKX2.2homeobox protein Nkx-2.2, NKX2BNK-2 homolog B

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
4821

Target Species:
Human, Mouse, Rat, Chicken

Form:
Purified

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)

Clone:
NX2/294

Conjugate:
Unconjugated

Gene Accession No.:
O95096

Gene Symbols:
NKX2-2

Immunogen:
Human full-length recombinant NKX2.2 protein (Uniprot: O95096)

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.

Content And Storage:
Store at 4C.

Isotype:
IgG2b κ

Img

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NBP229433

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Antigen:
Vimentin

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, ELISA 1-5ug/ml for coating, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1.0ug/ml, Immunohistochemistry-Frozen 0.5-1.0ug/ml, Knockout Validated 0.7 ug/ml

Gene Alias:
FLJ36605, vimentin

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
7431

Target Species:
Human, Porcine, Bovine, Canine, Chicken, Feline, Goat, Mouse (Negative), Rat (Negative)

Form:
Purified

Applications:
Western Blot, Flow Cytometry, ELISA, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
VM452

Conjugate:
Unconjugated

Gene Accession No.:
P08670

Gene Symbols:
VIM

Immunogen:
Recombinant full-length human vimentin protein (Uniprot: P08670)

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody reacts with a 58kDa protein identified as Vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of Vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-Vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-Vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain Vimentin, e.g. hepatoma and seminoma. Anti-Vimentin is also useful as a tissue process control reagent.

Content And Storage:
Store at 4C.

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP229440

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Antigen:
EGFR

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Flow Cytometry 0.5-1 μg/million cells in 0.1 mL, Immunohistochemistry, Immunohistochemistry-Paraffin 0.5-1.0 μg/mL, Protein Array, Immunofluorescence 1-2 μg/mL

Gene Alias:
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1

Host Species:
Mouse

Purification Method:
Protein A or G purified

Regulatory Status:
RUO

Gene ID (Entrez):
1956

Target Species:
Human, Mouse (Negative)

Form:
Purified

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Peptide Array, Immunofluorescence

Clone:
GFR450

Conjugate:
Unconjugated

Gene Accession No.:
P00533

Gene Symbols:
EGFR

Immunogen:
Recombinant extracellular domain of human EGFR protein (Uniprot: P00533)

Quantity:
0.1 mg

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

Content And Storage:
Store at 4C.

Isotype:
IgG2a κ

Img

Novus Biologicals™

NBP229446

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Antigen:
__

Classification:
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Dilution:
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Gene Alias:
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Host Species:
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Purification Method:
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Regulatory Status:
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Gene ID (Entrez):
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Target Species:
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Form:
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Clone:
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Conjugate:
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Gene Accession No.:
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Gene Symbols:
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Immunogen:
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Quantity:
1 mg

Primary or Secondary:
__

Test Specificity:
__

Content And Storage:
Store at 4°C. Protect from light.

Isotype:
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