NBP225221
MUC2 Antibody (CCP58), Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP225221-Each-of-1 | In Stock | ₹ 44,833.44 |
NBP225221 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,833.44
GST (18%): ₹ 8,070.019
Total Price: ₹ 52,903.459
Antigen
MUC2
Classification
Monoclonal
Concentration
0.2 mg/ml
Dilution
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Gene Alias
Intestinal mucin-2, MLP, MUC-2, mucin 2, intestinal/tracheal, mucin 2, oligomeric mucus/gel-forming, mucin-2, mucin-like protein, SMUC
Host Species
Mouse
Molecular Weight of Antigen
520 kDa
Quantity
0.1 mg
Research Discipline
Cancer, Cellular Markers, Inflammation, Signal Transduction
Gene ID (Entrez)
4583
Target Species
Human
Form
Purified
Applications
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Clone
CCP58
Conjugate
Unconjugated
Gene Accession No.
NP_002448
Gene Symbols
MUC2
Immunogen
A synthetic peptide of 29 amino acids, KYPTTTPISTTTMVTPTPTPTGTQTPTTT from MUC2 protein, coupled to KLH. (Uniprot: Q02817)
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This monoclonal antibody shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP(GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.
Content And Storage
Store at 4C.
Isotype
IgG1 κ
Related Products
Description
- MUC2 Monoclonal specifically detects MUC2 in Human samples
- It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
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Antigen: MUC2
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Gene Alias: Intestinal mucin-2, MLP, MUC-2, mucin 2, intestinal/tracheal, mucin 2, oligomeric mucus/gel-forming, mucin-2, mucin-like protein, SMUC
Host Species: Mouse
Molecular Weight of Antigen: 520 kDa
Quantity: 0.1 mg
Research Discipline: Cancer, Cellular Markers, Inflammation, Signal Transduction
Gene ID (Entrez): 4583
Target Species: Human
Form: Purified
Applications: Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Clone: CCP58
Conjugate: Unconjugated
Gene Accession No.: NP_002448
Gene Symbols: MUC2
Immunogen: A synthetic peptide of 29 amino acids, KYPTTTPISTTTMVTPTPTPTGTQTPTTT from MUC2 protein, coupled to KLH. (Uniprot: Q02817)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This monoclonal antibody shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP(GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
MUC2
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Western Blot 0.5-1ug/ml, Flow Cytometry 0.5-1ug/million cells, Immunocytochemistry/Immunofluorescence 1-2ug/ml, Immunoprecipitation 1-2ug/500ug protein lysate, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Gene Alias:
Intestinal mucin-2, MLP, MUC-2, mucin 2, intestinal/tracheal, mucin 2, oligomeric mucus/gel-forming, mucin-2, mucin-like protein, SMUC
Host Species:
Mouse
Molecular Weight of Antigen:
520 kDa
Quantity:
0.1 mg
Research Discipline:
Cancer, Cellular Markers, Inflammation, Signal Transduction
Gene ID (Entrez):
4583
Target Species:
Human
Form:
Purified
Applications:
Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin)
Clone:
CCP58
Conjugate:
Unconjugated
Gene Accession No.:
NP_002448
Gene Symbols:
MUC2
Immunogen:
A synthetic peptide of 29 amino acids, KYPTTTPISTTTMVTPTPTPTGTQTPTTT from MUC2 protein, coupled to KLH. (Uniprot: Q02817)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This monoclonal antibody shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP(GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine in about 65% of colonic carcinomas and about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast and clear cell-type carcinomas of the ovary.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: CD46
Classification: Monoclonal
Concentration: 0.2mg/mL
Dilution: Flow Cytometry 0.5-1ug/million cells in 0.1ml, SDS-Page, Immunofluorescence 0.5-1ug/ml
Gene Alias: AHUS2, CD46 antigen, CD46 molecule, complement regulatory protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 0.02 mg
Research Discipline: Cancer, Cell Biology, Cellular Markers, Immunology
Gene ID (Entrez): 4179
Target Species: Human
Form: Purified
Applications: Flow Cytometry, SDS-Page, Immunofluorescence
Clone: 122.2
Conjugate: Unconjugated
Gene Accession No.: NP_002380
Gene Symbols: CD46
Immunogen: A recombinant protein fragment specific for human CD46 was used as the immunogen.
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: CD46 acts as a cofactor for complement factor I, a serine protease, which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells, which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
CD46
Classification:
Monoclonal
Concentration:
0.2mg/mL
Dilution:
Flow Cytometry 0.5-1ug/million cells in 0.1ml, SDS-Page, Immunofluorescence 0.5-1ug/ml
Gene Alias:
AHUS2, CD46 antigen, CD46 molecule, complement regulatory protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.02 mg
Research Discipline:
Cancer, Cell Biology, Cellular Markers, Immunology
Gene ID (Entrez):
4179
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, SDS-Page, Immunofluorescence
Clone:
122.2
Conjugate:
Unconjugated
Gene Accession No.:
NP_002380
Gene Symbols:
CD46
Immunogen:
A recombinant protein fragment specific for human CD46 was used as the immunogen.
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
CD46 acts as a cofactor for complement factor I, a serine protease, which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells, which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: CD46
Classification: Monoclonal
Concentration: 0.2mg/mL
Dilution: Flow Cytometry 0.5-1ug/million cells in 0.1ml, SDS-Page, Immunofluorescence 0.5-1ug/ml
Gene Alias: AHUS2, CD46 antigen, CD46 molecule, complement regulatory protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 0.2 mg
Research Discipline: Cancer, Cell Biology, Cellular Markers, Immunology
Gene ID (Entrez): 4179
Target Species: Human
Form: Purified
Applications: Flow Cytometry, SDS-Page, Immunofluorescence
Clone: 122.2
Conjugate: Unconjugated
Gene Accession No.: NP_002380
Gene Symbols: CD46
Immunogen: A recombinant protein fragment specific for human CD46 was used as the immunogen.
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: CD46 acts as a cofactor for complement factor I, a serine protease, which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells, which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
CD46
Classification:
Monoclonal
Concentration:
0.2mg/mL
Dilution:
Flow Cytometry 0.5-1ug/million cells in 0.1ml, SDS-Page, Immunofluorescence 0.5-1ug/ml
Gene Alias:
AHUS2, CD46 antigen, CD46 molecule, complement regulatory protein, membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen), MIC10, TLXcomplement regulatory protein, trophoblast leucocyte common antigen, Trophoblast leukocyte common antigen, trophoblast-lymphocyte cross-reactive antigen
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.2 mg
Research Discipline:
Cancer, Cell Biology, Cellular Markers, Immunology
Gene ID (Entrez):
4179
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, SDS-Page, Immunofluorescence
Clone:
122.2
Conjugate:
Unconjugated
Gene Accession No.:
NP_002380
Gene Symbols:
CD46
Immunogen:
A recombinant protein fragment specific for human CD46 was used as the immunogen.
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
CD46 acts as a cofactor for complement factor I, a serine protease, which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. It may be involved in the fusion of the spermatozoa with the oocyte during fertilization. CD46 acts as a co-stimulatory factor for T-cells, which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity. A number of viral and bacterial pathogens seem to exploit this property and directly induce an immunosuppressive phenotype in T-cells by binding to CD46.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: CCR6
Classification: Monoclonal
Concentration: __
Dilution: Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias: BN-1, CC-CKR-6, CCR-6, CD196 antigen, chemokine (C-C motif) receptor 6, CKR-L3G-protein coupled receptor 29, CKRL3LARC receptor, CMKBR6STRL22, DRY6, GPR29C-C CKR-6, GPRCY4DRY-6, lymphocyte, 22
Host Species: Rat
Molecular Weight of Antigen: __
Quantity: 0.1 mL
Research Discipline: Cytokine Research, GPCR, Immunology, Innate Immunity, Signal Transduction
Gene ID (Entrez): 1235
Target Species: Human, Mouse
Form: Purified
Applications: Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: 18B9E6
Conjugate: Biotin
Gene Accession No.: __
Gene Symbols: CCR6
Immunogen: A recombinant protein consisting of the external domains of mouse CD196 (CCR6) was used as the immunogen for the antibody.
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This product reacts with Mouse.
Content And Storage: Store at 4C in the dark.
Isotype: IgG2a κ
Antigen:
CCR6
Classification:
Monoclonal
Concentration:
__
Dilution:
Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
BN-1, CC-CKR-6, CCR-6, CD196 antigen, chemokine (C-C motif) receptor 6, CKR-L3G-protein coupled receptor 29, CKRL3LARC receptor, CMKBR6STRL22, DRY6, GPR29C-C CKR-6, GPRCY4DRY-6, lymphocyte, 22
Host Species:
Rat
Molecular Weight of Antigen:
__
Quantity:
0.1 mL
Research Discipline:
Cytokine Research, GPCR, Immunology, Innate Immunity, Signal Transduction
Gene ID (Entrez):
1235
Target Species:
Human, Mouse
Form:
Purified
Applications:
Western Blot, Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
18B9E6
Conjugate:
Biotin
Gene Accession No.:
__
Gene Symbols:
CCR6
Immunogen:
A recombinant protein consisting of the external domains of mouse CD196 (CCR6) was used as the immunogen for the antibody.
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This product reacts with Mouse.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG2a κ