NBP229420
UCH-L1/PGP9.5 Antibody (13C4), Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP229420-Each-of-1 | In Stock | ₹ 44,833.44 |
NBP229420 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,833.44
GST (18%): ₹ 8,070.019
Total Price: ₹ 52,903.459
Antigen
UCH-L1/PGP9.5
Classification
Monoclonal
Concentration
0.2 mg/ml
Dilution
Western Blot 0.5-1 μg/mL, Simple Western 10 μg/mL, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1-2 μg/mL, Immunohistochemistry-Frozen 0.5-1.0 μg/mL
Gene Alias
EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
Content And Storage
Store at 4C.
Isotype
IgG2a κ
Applications
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Clone
13C4
Conjugate
Unconjugated
Gene Accession No.
P09936
Gene Symbols
UCHL1
Immunogen
UCH-L1/PGP9.5 protein from brain (Uniprot: P09936)
Quantity
0.1 mg
Research Discipline
Alzheimers Research, Cellular Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Neurotransmission
Gene ID (Entrez)
7345
Target Species
Human, Mouse, Rat, Porcine, Bovine, Canine, Guinea Pig, Rabbit, Sheep, Zebrafish
Form
Purified
Related Products
Description
- UCH-L1/PGP9.5 Monoclonal specifically detects UCH-L1/PGP9.5 in Human, Mouse, Rat, Porcine, Bovine, Canine, Guinea Pig, Rabbit, Sheep, Zebrafish samples
- It is validated for Western Blot, Simple Western, Immunocytochemistry/Immunofluorescence.
Compare Similar Items
Show Difference
Antigen: UCH-L1/PGP9.5
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Western Blot 0.5-1 μg/mL, Simple Western 10 μg/mL, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1-2 μg/mL, Immunohistochemistry-Frozen 0.5-1.0 μg/mL
Gene Alias: EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
Content And Storage: Store at 4C.
Isotype: IgG2a κ
Applications: Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Clone: 13C4
Conjugate: Unconjugated
Gene Accession No.: P09936
Gene Symbols: UCHL1
Immunogen: UCH-L1/PGP9.5 protein from brain (Uniprot: P09936)
Quantity: 0.1 mg
Research Discipline: Alzheimers Research, Cellular Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Neurotransmission
Gene ID (Entrez): 7345
Target Species: Human, Mouse, Rat, Porcine, Bovine, Canine, Guinea Pig, Rabbit, Sheep, Zebrafish
Form: Purified
Antigen:
UCH-L1/PGP9.5
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Western Blot 0.5-1 μg/mL, Simple Western 10 μg/mL, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1-2 μg/mL, Immunohistochemistry-Frozen 0.5-1.0 μg/mL
Gene Alias:
EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
Content And Storage:
Store at 4C.
Isotype:
IgG2a κ
Applications:
Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Frozen)
Clone:
13C4
Conjugate:
Unconjugated
Gene Accession No.:
P09936
Gene Symbols:
UCHL1
Immunogen:
UCH-L1/PGP9.5 protein from brain (Uniprot: P09936)
Quantity:
0.1 mg
Research Discipline:
Alzheimers Research, Cellular Markers, Neurodegeneration, Neuronal Cell Markers, Neuroscience, Neurotransmission
Gene ID (Entrez):
7345
Target Species:
Human, Mouse, Rat, Porcine, Bovine, Canine, Guinea Pig, Rabbit, Sheep, Zebrafish
Form:
Purified
Antigen: Bcl-10
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Western Blot 0.5-1 μg/mL, Flow Cytometry 0.5-1 μg/mL, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1-2 μg/mL, Immunoprecipitation 1-2 μg/500 μg protein lysate, Immunohistochemistry-Paraffin 0.5-1 μg/mL, Immunohistochemistry-Frozen 0.5-1 μg/mL
Gene Alias: B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10, Bcl-10, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CARMEN, caspase-recruiting domain-containing protein, cCARMEN, c-E10bcl-10, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, cellular-E10, hCLAP, Mammalian CARD-containing adapter molecule E10, mE10CARD containing molecule enhancing NF-kB
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFKB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: BL10/411
Conjugate: Unconjugated
Gene Accession No.: O95999
Gene Symbols: BCL10
Immunogen: Human Bcl-10 recombinant protein (epitope aa122-168) (Uniprot: O95999)
Quantity: 0.1 mg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): 8915
Target Species: Human
Form: Purified
Antigen:
Bcl-10
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Western Blot 0.5-1 μg/mL, Flow Cytometry 0.5-1 μg/mL, ELISA 1-5 μg/mL for coating, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1-2 μg/mL, Immunoprecipitation 1-2 μg/500 μg protein lysate, Immunohistochemistry-Paraffin 0.5-1 μg/mL, Immunohistochemistry-Frozen 0.5-1 μg/mL
Gene Alias:
B-cell CLL/lymphoma 10CIPERCLAPB-cell lymphoma/leukemia 10, Bcl-10, CARD-containing apoptotic signaling protein, CARD-containing molecule enhancing NF-kappa-B, CARD-containing proapoptotic protein, CARD-like apoptotic protein, CARMEN, caspase-recruiting domain-containing protein, cCARMEN, c-E10bcl-10, CED-3/ICH-1 prodomain homologous E10-like regulator, Cellular homolog of vCARMEN, cellular-E10, hCLAP, Mammalian CARD-containing adapter molecule E10, mE10CARD containing molecule enhancing NF-kB
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
BCL10, with an N-terminal caspase recruitment domain (CARD), is found in a number of apoptotic regulatory molecules. It was identified through its direct involvement in t(1;14) of mucosa-associated lymphoid tissue (MALT) lymphoma. Expression of BCL10 was shown to induce NFKB activation in a NIK-dependent pathway. This MAb labels subpopulations of normal B and T cells and is a useful tool for the sub-classification of lymphomas. In MALT lymphomas with the t(1;14) translocation, while 55% of MALT lymphomas lacking this translocation exhibited the same labeling pattern, although at a much lower level.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
BL10/411
Conjugate:
Unconjugated
Gene Accession No.:
O95999
Gene Symbols:
BCL10
Immunogen:
Human Bcl-10 recombinant protein (epitope aa122-168) (Uniprot: O95999)
Quantity:
0.1 mg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
8915
Target Species:
Human
Form:
Purified
Antigen: CD117/c-kit
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: ELISA 1-5ug/ml for coating, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Gene Alias: CD117, CD117 antigen, ckit, C-Kit, EC 2.7.10, EC 2.7.10.1, PBT, piebald trait, Proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, SCFRmast/stem cell growth factor receptor, soluble KIT variant 1, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone: C117/370
Conjugate: Unconjugated
Gene Accession No.: P10721
Gene Symbols: KIT
Immunogen: Recombinant human CD117/c-kit protein (Uniprot: P10721)
Quantity: 0.1 mg
Research Discipline: Cancer, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Phospho Specific, Protein Kinase, Signal Transduction, Stem Cell Markers, Tyrosine Kinases
Gene ID (Entrez): 3815
Target Species: Human
Form: Purified
Antigen:
CD117/c-kit
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
ELISA 1-5ug/ml for coating, Immunohistochemistry-Paraffin 0.5-1ug/ml, Immunohistochemistry-Frozen 0.5-1ug/ml
Gene Alias:
CD117, CD117 antigen, ckit, C-Kit, EC 2.7.10, EC 2.7.10.1, PBT, piebald trait, Proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, SCFRmast/stem cell growth factor receptor, soluble KIT variant 1, Tyrosine-protein kinase Kit, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog, v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene-like protein
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody recognizes a protein of 145kDa, identified as CD117/p145kit. It is found on a wide variety of tumor cells including follicular and papillary carcinoma of thyroid, adenocarcinomas from endometrium, lung, ovary, pancreas, and breast as well as malignant melanoma, endodermal sinus tumor, and small cell carcinoma. However, anti-CD117 has been particularly useful in differentiating gastrointestinal stromal tumors from Kaposi's sarcoma, tumors of smooth muscle origin, fibromatosis, and neural tumors of the GI tract. Anti-CD117 is also useful in recognizing myeloblasts in bone marrow biopsy and clot section.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
ELISA, Immunohistochemistry (Paraffin), Immunohistochemistry (Frozen)
Clone:
C117/370
Conjugate:
Unconjugated
Gene Accession No.:
P10721
Gene Symbols:
KIT
Immunogen:
Recombinant human CD117/c-kit protein (Uniprot: P10721)
Quantity:
0.1 mg
Research Discipline:
Cancer, Cellular Markers, Cytokine Research, Hematopoietic Stem Cell Markers, Immunology, Innate Immunity, Mast Cell Markers, Mesenchymal Stem Cell Markers, Phospho Specific, Protein Kinase, Signal Transduction, Stem Cell Markers, Tyrosine Kinases
Gene ID (Entrez):
3815
Target Species:
Human
Form:
Purified
Antigen: CD19
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 0.5-1.0ug/ml
Gene Alias: B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19 antigen, CD19 molecule, CVID3, Differentiation antigen CD19, MGC12802, T-cell surface antigen Leu-12
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin)
Clone: C19/366
Conjugate: Unconjugated
Gene Accession No.: P15391
Gene Symbols: CD19
Immunogen: Recombinant full-length human CD19 protein (Uniprot: P15391)
Quantity: 0.1 mg
Research Discipline: Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Signal Transduction, Stem Cell Lines, Stem Cell Markers
Gene ID (Entrez): 930
Target Species: Human
Form: Purified
Antigen:
CD19
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 0.5-1.0ug/ml
Gene Alias:
B4, B-lymphocyte antigen CD19, B-lymphocyte surface antigen B4, CD19 antigen, CD19 molecule, CVID3, Differentiation antigen CD19, MGC12802, T-cell surface antigen Leu-12
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
C19/366
Conjugate:
Unconjugated
Gene Accession No.:
P15391
Gene Symbols:
CD19
Immunogen:
Recombinant full-length human CD19 protein (Uniprot: P15391)
Quantity:
0.1 mg
Research Discipline:
Adaptive Immunity, Cytokine Research, Immunology, Innate Immunity, Mesenchymal Stem Cell Markers, Signal Transduction, Stem Cell Lines, Stem Cell Markers
Gene ID (Entrez):
930
Target Species:
Human
Form:
Purified