NBP247748B
TOX3 Antibody (TOX3/1123) - Azide and BSA Free, Novus Biologicals™
Manufacturer: Fischer Scientific
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Antigen
TOX3
Classification
Monoclonal
Concentration
1.0 mg/mL
Dilution
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Alias
CAG trinucleotide repeat-containing gene F9 protein, CAGF9trinucleotide repeat containing 9, TNRC9, TOX high mobility group box family member 3, Trinucleotide repeat-containing gene 9 protein
Host Species
Mouse
Molecular Weight of Antigen
63 kDa
Quantity
0.2 mg
Primary or Secondary
Primary
Test Specificity
It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Content And Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype
IgG2b κ
Applications
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Clone
TOX3/1123
Conjugate
Unconjugated
Formulation
PBS with No Preservative
Gene Symbols
TOX3
Immunogen
Recombinant fragment (139 Amino acid residues around aa 200-400) of human TOX3 protein
Purification Method
Protein A or G purified
Regulatory Status
RUO
Gene ID (Entrez)
27324
Target Species
Human
Form
Purified
Related Products
Description
- TOX3 Monoclonal specifically detects TOX3 in Human, Chicken samples
- It is validated for Western Blot, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Protein Array.
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Show Difference
Antigen: TOX3
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Alias: CAG trinucleotide repeat-containing gene F9 protein, CAGF9trinucleotide repeat containing 9, TNRC9, TOX high mobility group box family member 3, Trinucleotide repeat-containing gene 9 protein
Host Species: Mouse
Molecular Weight of Antigen: 63 kDa
Quantity: 0.2 mg
Primary or Secondary: Primary
Test Specificity: It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG2b κ
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Clone: TOX3/1123
Conjugate: Unconjugated
Formulation: PBS with No Preservative
Gene Symbols: TOX3
Immunogen: Recombinant fragment (139 Amino acid residues around aa 200-400) of human TOX3 protein
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 27324
Target Species: Human
Form: Purified
Antigen:
TOX3
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Dilution:
Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunohistochemistry-Paraffin : 0.5 - 1.0 ug/ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Alias:
CAG trinucleotide repeat-containing gene F9 protein, CAGF9trinucleotide repeat containing 9, TNRC9, TOX high mobility group box family member 3, Trinucleotide repeat-containing gene 9 protein
Host Species:
Mouse
Molecular Weight of Antigen:
63 kDa
Quantity:
0.2 mg
Primary or Secondary:
Primary
Test Specificity:
It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG2b κ
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Clone:
TOX3/1123
Conjugate:
Unconjugated
Formulation:
PBS with No Preservative
Gene Symbols:
TOX3
Immunogen:
Recombinant fragment (139 Amino acid residues around aa 200-400) of human TOX3 protein
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
27324
Target Species:
Human
Form:
Purified
Antigen: TOX3
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Alias: CAG trinucleotide repeat-containing gene F9 protein, CAGF9trinucleotide repeat containing 9, TNRC9, TOX high mobility group box family member 3, Trinucleotide repeat-containing gene 9 protein
Host Species: Mouse
Molecular Weight of Antigen: 63 kDa
Quantity: 0.1 mg
Primary or Secondary: Primary
Test Specificity: It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1 κ
Applications: Western Blot, Flow Cytometry, Immunofluorescence, CyTOF
Clone: TOX3/1124
Conjugate: Unconjugated
Formulation: PBS with No Preservative
Gene Symbols: TOX3
Immunogen: Recombinant fragment (139 Amino acid residues around aa 200-400) of human TOX3 protein
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 27324
Target Species: Human
Form: Purified
Antigen:
TOX3
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Dilution:
Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Alias:
CAG trinucleotide repeat-containing gene F9 protein, CAGF9trinucleotide repeat containing 9, TNRC9, TOX high mobility group box family member 3, Trinucleotide repeat-containing gene 9 protein
Host Species:
Mouse
Molecular Weight of Antigen:
63 kDa
Quantity:
0.1 mg
Primary or Secondary:
Primary
Test Specificity:
It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1 κ
Applications:
Western Blot, Flow Cytometry, Immunofluorescence, CyTOF
Clone:
TOX3/1124
Conjugate:
Unconjugated
Formulation:
PBS with No Preservative
Gene Symbols:
TOX3
Immunogen:
Recombinant fragment (139 Amino acid residues around aa 200-400) of human TOX3 protein
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
27324
Target Species:
Human
Form:
Purified
Antigen: TOX3
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Alias: CAG trinucleotide repeat-containing gene F9 protein, CAGF9trinucleotide repeat containing 9, TNRC9, TOX high mobility group box family member 3, Trinucleotide repeat-containing gene 9 protein
Host Species: Mouse
Molecular Weight of Antigen: 63 kDa
Quantity: 0.2 mg
Primary or Secondary: Primary
Test Specificity: It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgG1 κ
Applications: Western Blot, Flow Cytometry, Immunofluorescence, CyTOF
Clone: TOX3/1124
Conjugate: Unconjugated
Formulation: PBS with No Preservative
Gene Symbols: TOX3
Immunogen: Recombinant fragment (139 Amino acid residues around aa 200-400) of human TOX3 protein
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 27324
Target Species: Human
Form: Purified
Antigen:
TOX3
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Dilution:
Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
Gene Alias:
CAG trinucleotide repeat-containing gene F9 protein, CAGF9trinucleotide repeat containing 9, TNRC9, TOX high mobility group box family member 3, Trinucleotide repeat-containing gene 9 protein
Host Species:
Mouse
Molecular Weight of Antigen:
63 kDa
Quantity:
0.2 mg
Primary or Secondary:
Primary
Test Specificity:
It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgG1 κ
Applications:
Western Blot, Flow Cytometry, Immunofluorescence, CyTOF
Clone:
TOX3/1124
Conjugate:
Unconjugated
Formulation:
PBS with No Preservative
Gene Symbols:
TOX3
Immunogen:
Recombinant fragment (139 Amino acid residues around aa 200-400) of human TOX3 protein
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
27324
Target Species:
Human
Form:
Purified
Antigen: Podocalyxin Like
Classification: Monoclonal
Concentration: 1.0 mg/mL
Dilution: Flow Cytometry : 5 - 10 ul/million cells in 0.1ml, Immunohistochemistry-Paraffin : 1:50 - 1:100, Immunofluorescence : 1:25 - 1:50, CyTOF-ready
Gene Alias: Gp200MGC138240, PCLP1, PCLP-1, PCLPGCTM-2 antigen, PCpodocalyxin, podocalyxin-like, Podocalyxin-like protein 1
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 0.1 mg
Primary or Secondary: Primary
Test Specificity: Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
Content And Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype: IgM
Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Clone: 2A4
Conjugate: Unconjugated
Formulation: PBS with No Preservative
Gene Symbols: PODXL
Immunogen: A recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain of human podocalyxin.
Purification Method: Protein A or G purified
Regulatory Status: RUO
Gene ID (Entrez): 5420
Target Species: Human, Rat, Rabbit
Form: Purified
Antigen:
Podocalyxin Like
Classification:
Monoclonal
Concentration:
1.0 mg/mL
Dilution:
Flow Cytometry : 5 - 10 ul/million cells in 0.1ml, Immunohistochemistry-Paraffin : 1:50 - 1:100, Immunofluorescence : 1:25 - 1:50, CyTOF-ready
Gene Alias:
Gp200MGC138240, PCLP1, PCLP-1, PCLPGCTM-2 antigen, PCpodocalyxin, podocalyxin-like, Podocalyxin-like protein 1
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
0.1 mg
Primary or Secondary:
Primary
Test Specificity:
Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Isotype:
IgM
Applications:
Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence, CyTOF
Clone:
2A4
Conjugate:
Unconjugated
Formulation:
PBS with No Preservative
Gene Symbols:
PODXL
Immunogen:
A recombinant protein fragment containing the intracellular, transmembrane, and part of the extracellular domain of human podocalyxin.
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Gene ID (Entrez):
5420
Target Species:
Human, Rat, Rabbit
Form:
Purified