Manufacturer: Fischer Scientific
Pack Size | SKU | Availability | Price |
---|---|---|---|
Each of 1 | NBP247749A-Each-of-1 | In Stock | ₹ 53,688.90 |
NBP247749A - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,688.90
GST (18%): ₹ 9,664.002
Total Price: ₹ 63,352.902
TOX3
Monoclonal
1.0 mg/mL
Western Blot : 0.5 - 1.0 ug/ml, Flow Cytometry : 0.5 - 1 ug/million cells in 0.1 ml, Immunofluorescence : 0.5 - 1.0 ug/ml, CyTOF-ready
CAG trinucleotide repeat-containing gene F9 protein, CAGF9trinucleotide repeat containing 9, TNRC9, TOX high mobility group box family member 3, Trinucleotide repeat-containing gene 9 protein
Mouse
63 kDa
0.1 mg
Primary
It recognizes a 63kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2+-dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
IgG1 κ
Western Blot, Flow Cytometry, Immunofluorescence, CyTOF
TOX3/1124
Unconjugated
PBS with No Preservative
TOX3
Recombinant fragment (139 Amino acid residues around aa 200-400) of human TOX3 protein
Protein A or G purified
RUO
27324
Human
Purified