NBP248203
EGFR Antibody (SPM622) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248203-Each-of-1 | In Stock | ₹ 45,860.16 |
NBP248203 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,860.16
GST (18%): ₹ 8,254.829
Total Price: ₹ 54,114.989
Antigen
EGFR
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
EGFR
Immunogen
Human EGFR purified from A431 cells
Quantity
7 mL
Research Discipline
Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers, Cellular Signaling, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases
Gene ID (Entrez)
1956
Target Species
Human
Form
Purified
Applications
Immunohistochemistry (Paraffin)
Clone
SPM622
Dilution
Immunohistochemistry-Paraffin
Gene Alias
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
Host Species
Mouse
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, Beta cellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Content And Storage
Store at 4C.
Isotype
IgG2a κ
Related Products
Description
- EGFR Monoclonal specifically detects EGFR in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
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Antigen: EGFR
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: EGFR
Immunogen: Human EGFR purified from A431 cells
Quantity: 7 mL
Research Discipline: Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers, Cellular Signaling, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases
Gene ID (Entrez): 1956
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: SPM622
Dilution: Immunohistochemistry-Paraffin
Gene Alias: avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, Beta cellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Content And Storage: Store at 4C.
Isotype: IgG2a κ
Antigen:
EGFR
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
EGFR
Immunogen:
Human EGFR purified from A431 cells
Quantity:
7 mL
Research Discipline:
Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers, Cellular Signaling, Growth and Development, Hypoxia, Phospho Specific, Signal Transduction, Tumor Suppressors, Tyrosine Kinases
Gene ID (Entrez):
1956
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
SPM622
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EC 2.7.10, EC 2.7.10.1, epidermal growth factor receptor, epidermal growth factor receptor (avian erythroblastic leukemia viral (v-erb-b)oncogene homolog), ERBB, ErbB1, ERBB1PIG61, HER1, mENA, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, Beta cellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.
Content And Storage:
Store at 4C.
Isotype:
IgG2a κ
Antigen: Calponin 1
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CNN1
Immunogen: Crude human uterus extract
Quantity: 7 mL
Research Discipline: Cancer, Cytoskeleton Markers
Gene ID (Entrez): 1264
Target Species: Human, Rat
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: SPM169
Dilution: Immunohistochemistry-Paraffin
Gene Alias: Basic calponin, calponin 1, basic, smooth muscle, Calponin H1, smooth muscle, calponins, basic, Sm-Calp, SMCCcalponin-1
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this monoclonal antibody reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Calponin 1
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CNN1
Immunogen:
Crude human uterus extract
Quantity:
7 mL
Research Discipline:
Cancer, Cytoskeleton Markers
Gene ID (Entrez):
1264
Target Species:
Human, Rat
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
SPM169
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
Basic calponin, calponin 1, basic, smooth muscle, Calponin H1, smooth muscle, calponins, basic, Sm-Calp, SMCCcalponin-1
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this monoclonal antibody reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: Calponin 1
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CNN1
Immunogen: Recombinant full-length human Calponin 1 protein (Uniprot: P51911)
Quantity: 7 mL
Research Discipline: Cancer, Cytoskeleton Markers
Gene ID (Entrez): 1264
Target Species: Human, Rat
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: CNN1/832
Dilution: Immunohistochemistry-Paraffin
Gene Alias: Basic calponin, calponin 1, basic, smooth muscle, Calponin H1, smooth muscle, calponins, basic, Sm-Calp, SMCCcalponin-1
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this monoclonal antibody reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Calponin 1
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CNN1
Immunogen:
Recombinant full-length human Calponin 1 protein (Uniprot: P51911)
Quantity:
7 mL
Research Discipline:
Cancer, Cytoskeleton Markers
Gene ID (Entrez):
1264
Target Species:
Human, Rat
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
CNN1/832
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
Basic calponin, calponin 1, basic, smooth muscle, Calponin H1, smooth muscle, calponins, basic, Sm-Calp, SMCCcalponin-1
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this monoclonal antibody reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Antigen: Calponin 1
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: CNN1
Immunogen: Recombinant full-length human Calponin 1 protein (Calponin 1/832); Crude human uterus extract (CALP) (Uniprot: P51911)
Quantity: 7 mL
Research Discipline: Cancer, Cytoskeleton Markers
Gene ID (Entrez): 1264
Target Species: Human, Rat
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: CNN1/832 + CALP
Dilution: Immunohistochemistry-Paraffin
Gene Alias: Basic calponin, calponin 1, basic, smooth muscle, Calponin H1, smooth muscle, calponins, basic, Sm-Calp, SMCCcalponin-1
Host Species: Mouse
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this monoclonal antibody reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Antigen:
Calponin 1
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
CNN1
Immunogen:
Recombinant full-length human Calponin 1 protein (Calponin 1/832); Crude human uterus extract (CALP) (Uniprot: P51911)
Quantity:
7 mL
Research Discipline:
Cancer, Cytoskeleton Markers
Gene ID (Entrez):
1264
Target Species:
Human, Rat
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
CNN1/832 + CALP
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
Basic calponin, calponin 1, basic, smooth muscle, Calponin H1, smooth muscle, calponins, basic, Sm-Calp, SMCCcalponin-1
Host Species:
Mouse
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Multiple isoelectric variants of calponin have been identified, however only two molecular weight isoforms exist; a 34kDa form and a 29kDa form. Expression of the 29kDa form, I-calponin, is primarily restricted to muscle of the urogenital tract, whereas the higher molecular weight variant has been demonstrated in vascular and visceral smooth muscle. In Western blotting, this monoclonal antibody reacts with only the 34kDa form of calponin in extracts of human aortic medial smooth muscle and is unreactive with fibroblast extracts of cultivated human foreskin. Calponin is a calmodulin, F-actin and tropomyosin binding protein, which is thought to be involved in the regulation of smooth muscle contraction. Calponin expression is restricted to smooth muscle cells and has been shown to be a marker of the differentiated (contractile) phenotype of developing smooth muscle.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ