NBP248293
NF-L Antibody (SPM204) - IHC-Prediluted, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP248293-Each-of-1 | In Stock | ₹ 44,833.44 |
NBP248293 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,833.44
GST (18%): ₹ 8,070.019
Total Price: ₹ 52,903.459
Antigen
NF-L
Classification
Monoclonal
Conjugate
Unconjugated
Formulation
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols
NEFL
Immunogen
Neurofilament purified from human brain
Purification Method
Protein A or G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
This monoclonal antibody reacts with a 68kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Content And Storage
Store at 4C.
Isotype
IgG1 κ
Applications
Immunohistochemistry (Paraffin)
Clone
SPM204
Dilution
Immunohistochemistry-Paraffin
Gene Alias
68 kDa neurofilament protein, neurofilament protein, light chain, neurofilament subunit NF-L, Neurofilament triplet L protein, neurofilament, light polypeptide, neurofilament-light, NF68FLJ53642, NF-L, NFLlight polypeptide 68kDa
Host Species
Mouse
Molecular Weight of Antigen
68 kDa
Quantity
7 mL
Research Discipline
Autophagy, Cellular Markers, Cytoskeleton Markers, Neurodegeneration, Neurofilaments, Neuronal Cell Markers, Neuroscience
Gene ID (Entrez)
4747
Target Species
Human, Rat, Porcine, Chicken, Primate
Form
Purified
Related Products
Description
- NF-L Monoclonal specifically detects NF-L in Human, Rat, Porcine, Bovine, Chicken samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
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Antigen: NF-L
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: NEFL
Immunogen: Neurofilament purified from human brain
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody reacts with a 68kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin)
Clone: SPM204
Dilution: Immunohistochemistry-Paraffin
Gene Alias: 68 kDa neurofilament protein, neurofilament protein, light chain, neurofilament subunit NF-L, Neurofilament triplet L protein, neurofilament, light polypeptide, neurofilament-light, NF68FLJ53642, NF-L, NFLlight polypeptide 68kDa
Host Species: Mouse
Molecular Weight of Antigen: 68 kDa
Quantity: 7 mL
Research Discipline: Autophagy, Cellular Markers, Cytoskeleton Markers, Neurodegeneration, Neurofilaments, Neuronal Cell Markers, Neuroscience
Gene ID (Entrez): 4747
Target Species: Human, Rat, Porcine, Chicken, Primate
Form: Purified
Antigen:
NF-L
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
NEFL
Immunogen:
Neurofilament purified from human brain
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
This monoclonal antibody reacts with a 68kDa protein, identified as light sub-unit of neurofilaments (NF-L). Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H). Anti-neurofilament stains a number of neural, neuroendocrine, and endocrine tumors. Neuromas, ganglioneuromas, gangliogliomas, ganglioneuroblastomas, and neuroblastomas stain positively for anti-neurofilament. Neurofilaments are also present in paragangliomas as well as adrenal and extra-adrenal pheochromocytomas. Carcinoids, neuroendocrine carcinomas of the skin, and oat cell carcinomas of the lung also express neurofilament.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
SPM204
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
68 kDa neurofilament protein, neurofilament protein, light chain, neurofilament subunit NF-L, Neurofilament triplet L protein, neurofilament, light polypeptide, neurofilament-light, NF68FLJ53642, NF-L, NFLlight polypeptide 68kDa
Host Species:
Mouse
Molecular Weight of Antigen:
68 kDa
Quantity:
7 mL
Research Discipline:
Autophagy, Cellular Markers, Cytoskeleton Markers, Neurodegeneration, Neurofilaments, Neuronal Cell Markers, Neuroscience
Gene ID (Entrez):
4747
Target Species:
Human, Rat, Porcine, Chicken, Primate
Form:
Purified
Antigen: NGFR/TNFRSF16/p75NTR
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: NGFR
Immunogen: NGFR from A875 melanoma cells
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone: NGFR5
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias: CD271, CD271 antigen, Gp80-LNGFR, member 16, nerve growth factor receptor, NGF receptor, p75 ICD, TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16), tumor necrosis factor receptor superfamily member 16
Host Species: Mouse
Molecular Weight of Antigen: 75 kDa
Quantity: 7 mL
Research Discipline: Apoptosis, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Gene ID (Entrez): 4804
Target Species: Human, Feline, Ferret, Monkey, Baboon, Rabbit, Mouse (Negative), Rat (Negative)
Form: Purified
Antigen:
NGFR/TNFRSF16/p75NTR
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
NGFR
Immunogen:
NGFR from A875 melanoma cells
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin)
Clone:
NGFR5
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin
Gene Alias:
CD271, CD271 antigen, Gp80-LNGFR, member 16, nerve growth factor receptor, NGF receptor, p75 ICD, TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16), tumor necrosis factor receptor superfamily member 16
Host Species:
Mouse
Molecular Weight of Antigen:
75 kDa
Quantity:
7 mL
Research Discipline:
Apoptosis, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Gene ID (Entrez):
4804
Target Species:
Human, Feline, Ferret, Monkey, Baboon, Rabbit, Mouse (Negative), Rat (Negative)
Form:
Purified
Antigen: NGFR/TNFRSF16/p75NTR
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: NGFR
Immunogen: NGFR from A875 melanoma cells
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin)
Clone: SPM299
Dilution: Immunohistochemistry-Paraffin
Gene Alias: CD271, CD271 antigen, Gp80-LNGFR, member 16, nerve growth factor receptor, NGF receptor, p75 ICD, TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16), tumor necrosis factor receptor superfamily member 16
Host Species: Mouse
Molecular Weight of Antigen: 75 kDa
Quantity: 7 mL
Research Discipline: Apoptosis, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Gene ID (Entrez): 4804
Target Species: Human, Feline, Ferret, Monkey, Baboon, Rabbit, Mouse (Negative), Rat (Negative)
Form: Purified
Antigen:
NGFR/TNFRSF16/p75NTR
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
NGFR
Immunogen:
NGFR from A875 melanoma cells
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). Its epitope spans in aa 1-160 of extracellular domain of NGFR/NTR. NGF-receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. NGF is important for the development, differentiation, and survival of variety of neuronal and non-neuronal cells. Its action is mediated by binding two distinct receptors, the high affinity p140 and low affinity p75.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
SPM299
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
CD271, CD271 antigen, Gp80-LNGFR, member 16, nerve growth factor receptor, NGF receptor, p75 ICD, TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16), tumor necrosis factor receptor superfamily member 16
Host Species:
Mouse
Molecular Weight of Antigen:
75 kDa
Quantity:
7 mL
Research Discipline:
Apoptosis, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Gene ID (Entrez):
4804
Target Species:
Human, Feline, Ferret, Monkey, Baboon, Rabbit, Mouse (Negative), Rat (Negative)
Form:
Purified
Antigen: NGFR/TNFRSF16/p75NTR
Classification: Monoclonal
Conjugate: Unconjugated
Formulation: 10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols: NGFR
Immunogen: Recombinant human NGFR/TNFRSF16/p75NTR protein (Uniprot: P08138)
Purification Method: Protein A or G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
Content And Storage: Store at 4C.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin)
Clone: NTR/912
Dilution: Immunohistochemistry-Paraffin
Gene Alias: CD271, CD271 antigen, Gp80-LNGFR, member 16, nerve growth factor receptor, NGF receptor, p75 ICD, TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16), tumor necrosis factor receptor superfamily member 16
Host Species: Mouse
Molecular Weight of Antigen: 75 kDa
Quantity: 7 mL
Research Discipline: Apoptosis, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Gene ID (Entrez): 4804
Target Species: Human, Primate, Mouse (Negative), Rat (Negative)
Form: Purified
Antigen:
NGFR/TNFRSF16/p75NTR
Classification:
Monoclonal
Conjugate:
Unconjugated
Formulation:
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
Gene Symbols:
NGFR
Immunogen:
Recombinant human NGFR/TNFRSF16/p75NTR protein (Uniprot: P08138)
Purification Method:
Protein A or G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
Content And Storage:
Store at 4C.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
NTR/912
Dilution:
Immunohistochemistry-Paraffin
Gene Alias:
CD271, CD271 antigen, Gp80-LNGFR, member 16, nerve growth factor receptor, NGF receptor, p75 ICD, TNFRSF16nerve growth factor receptor (TNFR superfamily, member 16), tumor necrosis factor receptor superfamily member 16
Host Species:
Mouse
Molecular Weight of Antigen:
75 kDa
Quantity:
7 mL
Research Discipline:
Apoptosis, Neuronal Cell Markers, Neuronal Stem Cell Markers, Neuroscience, Stem Cell Markers
Gene ID (Entrez):
4804
Target Species:
Human, Primate, Mouse (Negative), Rat (Negative)
Form:
Purified