Manufacturer: Novus Biologicals
Pack Size | SKU | Availability | Price |
---|---|---|---|
Each of 1 | NBP248472-Each-of-1 | In Stock | ₹ 44,833.44 |
NBP248472 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,833.44
GST (18%): ₹ 8,070.019
Total Price: ₹ 52,903.459
TOP1MT
Monoclonal
Unconjugated
10mM PBS and 0.05% BSA with 0.05% Sodium Azide
TOP1MT
Recombinant full-length human TOP1MT protein (Uniprot: Q969P6 )
Protein A or G purified
RUO
116447
Human
Purified
Immunohistochemistry, Immunohistochemistry (Paraffin)
TOP1MT/488
Immunohistochemistry, Immunohistochemistry-Paraffin
mitochondrial, mitochondrial DNA topoisomerase I, topoisomerase (DNA) I, mitochondrial
Mouse
70 kDa
7 mL
Primary
DNA topoisomerases are nuclear enzymes that regulate the topological structure of DNA in eukaryotic cells by transiently breaking and rejoining DNA strands. Due to their roles in DNA replication, recombination, and transcription, DNA topoisomerases have been identified as targets of numerous anticancer drugs. Mitochondrial Topo I (DNA topoisomerase I, mitochondrial) is a 601 amino acid protein that primarily acts to relieve DNA strain that may occur during duplication of mitochondrial DNA. As a type IB topoisomerase, mitochondrial Topo I requires a divalent metal, either, calcium or magnesium, as well as an alkaline pH for optimal activity.
Store at 4C.
IgG2b κ