Serpin A3/alpha 1-Antichymotrypsin Antibody (AACT/1451), DyLight 488, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP254339G-Each-of-1 | In Stock | ₹ 53,688.90 |
NBP254339G - Each of 1
In Stock
Quantity
1
Base Price: ₹ 53,688.90
GST (18%): ₹ 9,664.002
Total Price: ₹ 63,352.902
Antigen
Serpin A3/alpha 1-Antichymotrypsin
Classification
Monoclonal
Conjugate
DyLight 488
Formulation
50 mM sodium borate with 0.05% sodium azide
Gene Symbols
SERPINA3
Immunogen
Recombinant human Serpin A3/alpha 1-Antichymotrypsin protein fragment (around aa 49-187) (exact sequence is proprietary) (Uniprot: P01011)
Primary or Secondary
Primary
Test Specificity
It recognizes a protein of 65-76kDa, which is identified antichymotrypsin (AACT). AACT is a plasma protease inhibitor synthesized in the liver as a single glycopeptide chain. In human, the normal serum level of AACT is about one-tenth that of their concentrations in plasma increase in response to trauma, surgery and infection. Elevated levels of AACT are widely, but not universally, reported in the cerebrospinal fluid and plasma of AD patients. Prostate-specific antigen (PSA) and its SDS-stable complex with AACT are in widespread use as markers for the diagnosis of prostate cancer. AACT deficiency may also be a possible cause of chronic liver disease. AACT antibody reacts with histiocytes and histiocytic neoplasms. It is widely used to identify histiocytes and tumors derived from them. Acinar tumors of the pancreas and salivary gland may also exhibit AACT positivity.
Content And Storage
Store at 4°C in the dark.
Applications
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone
AACT/1451
Dilution
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias
AACTMGC88254, ACTGIG25, alpha-1-antichymotrypsin, antitrypsin), member 3, Cell growth-inhibiting gene 24/25 protein, growth-inhibiting protein 24, growth-inhibiting protein 25, member 3, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, serine (or cysteine) proteinase inhibitor, clade A, member 3, Serpin A3, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)
Host Species
Mouse
Quantity
0.1 mL
Gene ID (Entrez)
12
Target Species
Human
Isotype
IgG1
Description
- Serpin A3/alpha 1-Antichymotrypsin Monoclonal specifically detects Serpin A3/alpha 1-Antichymotrypsin in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
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Antigen: Serpin A3/alpha 1-Antichymotrypsin
Classification: Monoclonal
Conjugate: DyLight 488
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: SERPINA3
Immunogen: Recombinant human Serpin A3/alpha 1-Antichymotrypsin protein fragment (around aa 49-187) (exact sequence is proprietary) (Uniprot: P01011)
Primary or Secondary: Primary
Test Specificity: It recognizes a protein of 65-76kDa, which is identified antichymotrypsin (AACT). AACT is a plasma protease inhibitor synthesized in the liver as a single glycopeptide chain. In human, the normal serum level of AACT is about one-tenth that of their concentrations in plasma increase in response to trauma, surgery and infection. Elevated levels of AACT are widely, but not universally, reported in the cerebrospinal fluid and plasma of AD patients. Prostate-specific antigen (PSA) and its SDS-stable complex with AACT are in widespread use as markers for the diagnosis of prostate cancer. AACT deficiency may also be a possible cause of chronic liver disease. AACT antibody reacts with histiocytes and histiocytic neoplasms. It is widely used to identify histiocytes and tumors derived from them. Acinar tumors of the pancreas and salivary gland may also exhibit AACT positivity.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: AACT/1451
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: AACTMGC88254, ACTGIG25, alpha-1-antichymotrypsin, antitrypsin), member 3, Cell growth-inhibiting gene 24/25 protein, growth-inhibiting protein 24, growth-inhibiting protein 25, member 3, serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, serine (or cysteine) proteinase inhibitor, clade A, member 3, Serpin A3, serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin)
Host Species: Mouse
Quantity: 0.1 mL
Gene ID (Entrez): 12
Target Species: Human
Isotype: IgG1
Antigen: CD43/Sialophorin
Classification: Monoclonal
Conjugate: DyLight 488
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: SPN
Immunogen: Recombinant full-length human CD43/Sialophorin protein (Uniprot: P16150)
Primary or Secondary: Primary
Test Specificity: It recognizes a cell surface glycoprotein of 95/115/135kDa (depending upon the extent of glycosylation), identified as CD43. 70-90% of T-cell lymphomas and from 22-37% of B-cell lymphomas express CD43. No reactivity has been observed with reactive B-cells. So a B-lineage population that co-expresses CD43 is highly likely to be a malignant lymphoma, especially a low-grade lymphoma, rather than a reactive B-cell population. When CD43 antibody is used in combination with anti-CD20, effective immunophenotyping of the lymphomas in formalin-fixed tissues can be obtained. Co-staining of a lymphoid infiltrate with anti-CD20 and anti-CD43 argues against a reactive process and favors a diagnosis of lymphoma.
Content And Storage: Store at 4°C in the dark.
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: SPN/1766R
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: CD43 antigen, CD43), Galactoglycoprotein, GALGP, Leukocyte sialoglycoprotein, Sialophorin, sialophorin (gpL115, leukosialin, CD43)
Host Species: Rabbit
Quantity: 0.1 mL
Gene ID (Entrez): 6693
Target Species: Human
Isotype: IgG
Antigen: MUC1
Classification: Monoclonal
Conjugate: DyLight 488
Formulation: 50 mM sodium borate with 0.05% sodium azide
Gene Symbols: MUC1
Immunogen: Recombinant human MUC1 protein (Uniprot: P15941 )
Primary or Secondary: Primary
Test Specificity: This monoclonal antibody reacts with MUC1, a large transmembrane glycoprotein expressed on the ductal surface of normal glandular epithelia. The dominant epitope of this monoclonal antibody involves both amino acids as well as sugar moieties. Neuraminidase treatment destroys the antigen. It is a very good tracer agent in CA15.3 assays. The extracellular domain of MUC1 largely consists of a highly conserved, O-glycosylated 20 amino acids tandem repeat which can occur 30-100 times per molecule depending on the length of the allele involved. In the vast majority of human carcinomas this protein is up-regulated and poorly glycosylated and appears on the cell surface in a non-polarized fashion.
Content And Storage: Store at 4°C in the dark.
Applications: Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: rMUC1/960
Dilution: Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
Gene Alias: Breast carcinoma-associated antigen DF3, Carcinoma-associated mucin, CD227, CD227 antigen, DF3 antigen, EMA, episialin, H23 antigen, H23AG, KL-6, MAM6, MUC-1, MUC1/ZD, mucin 1, cell surface associated, mucin 1, transmembrane, mucin-1, Peanut-reactive urinary mucin, PEMMUC-1/SEC, PEMT, Polymorphic epithelial mucin, PUMMUC-1/X, tumor associated epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
Host Species: Mouse
Quantity: 0.1 mL
Gene ID (Entrez): 4582
Target Species: Human
Isotype: IgG2b κ