NBP254507G

HLA DQ/DR/DP Antibody (CR3/43), DyLight 488, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP254507G-Each-of-1 In Stock ₹ 54,245.04

NBP254507G - Each of 1

₹ 54,245.04

In Stock

Quantity

1

Base Price: ₹ 54,245.04

GST (18%): ₹ 9,764.107

Total Price: ₹ 64,009.147

Antigen

HLA DPB1

Classification

Monoclonal

Conjugate

DyLight 488

Formulation

50 mM sodium borate with 0.05% sodium azide

Gene Symbols

HLA-DPB1

Immunogen

Cells from human tonsil

Primary or Secondary

Primary

Test Specificity

Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36kDa) and a chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.

Content And Storage

Store at 4°C in the dark.

Applications

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone

CR3/43

Dilution

Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias

DP beta 1 chain, DPB1, HLA class II histocompatibility antigen, DP(W4) beta chain, HLA DP14-beta chain, HLA-DP histocompatibility type, beta-1 subunit, HLA-DP1B, HLA-DPB, major histocompatibility complex class II HLA DPB1 protein, major histocompatibility complex, class II, DP beta 1, MHC class II antigen beta chain, MHC class II antigen DP beta 1 chain, MHC class II antigen DPB1, MHC class II antigen DPbeta1, MHC class II HLA-DP-beta, MHC HLA DPB1

Host Species

Mouse

Quantity

0.1 mL

Gene ID (Entrez)

3115

Target Species

Human

Isotype

IgG1 κ

Related Products

Img

Novus Biologicals

NP24806A350

--

Img

Novus Biologicals

NP24806A532

--

Img

Novus Biologicals

NBP47672B

--

Img

Novus Biologicals

NP144924A30

--

Img

Abnova Corporation

89-934-273

--

Img

Abnova Corporation

89-934-276

--

Img

Abnova Corporation

89-934-277

--

Img

Abnova Corporation

89-934-275

--

Description

  • HLA DPB1 Monoclonal specifically detects HLA DPB1 in Human samples
  • It is validated for Western Blot, Flow Cytometry, ELISA, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Compare Similar Items

Show Difference

Img

Novus Biologicals

NBP254507G

--


Antigen:
HLA DPB1

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
HLA-DPB1

Immunogen:
Cells from human tonsil

Primary or Secondary:
Primary

Test Specificity:
Reacts with a common epitope of human major histocompatibility (MHC) class II antigens, HLA-DP, -DQ and -DR. Human MHC class II antigens are transmembrane glycoproteins composed of an chain (36kDa) and a chain (27kDa). They are expressed primarily on antigen presenting cells such as B lymphocytes, monocytes, macrophages, and thymic epithelial cells and are also present on activated T lymphocytes. Human MHC class II genes are located in the HLA-D region that encodes at least six and ten chain genes. Three loci, DR, DQ and DP, encode the major expressed products of the human class II region. The human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells. They, therefore, have a critical role in the initiation of the immune response. It has been shown that some autoimmune diseases are associated with certain class II alleles.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
CR3/43

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
DP beta 1 chain, DPB1, HLA class II histocompatibility antigen, DP(W4) beta chain, HLA DP14-beta chain, HLA-DP histocompatibility type, beta-1 subunit, HLA-DP1B, HLA-DPB, major histocompatibility complex class II HLA DPB1 protein, major histocompatibility complex, class II, DP beta 1, MHC class II antigen beta chain, MHC class II antigen DP beta 1 chain, MHC class II antigen DPB1, MHC class II antigen DPbeta1, MHC class II HLA-DP-beta, MHC HLA DPB1

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
3115

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP254512G

--


Antigen:
Kappa Light Chain

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
IGKC

Immunogen:
Recombinant human full-length Ig kappa chain

Primary or Secondary:
Primary

Test Specificity:
This monoclonal antibody is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Content And Storage:
Store at 4°C in the dark.

Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin)

Clone:
KLC1278

Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin

Gene Alias:
HCAK1, IGKCD, immunoglobulin kappa constant, Km, MGC111575, MGC62011, MGC72072, MGC88770, MGC88771, MGC88809

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
3514

Target Species:
Human

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP254519G

--


Antigen:
Desmocollin-2

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
DSC2

Immunogen:
Human desmocollin-2 extracellular domain (exact sequence is proprietary)

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
7G6

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
ARVD11, Cadherin family member 2, CDHF2DGII/III, desmocollin 2, desmocollin-2, Desmocollin-3, Desmosomal glycoprotein II, desmosomal glycoprotein II/III, Desmosomal glycoprotein III, DG2, DSC3DKFZp686I11137

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
1824

Target Species:
Human, Mouse, Rat

Isotype:
IgG1 κ

Img

Novus Biologicals

NBP254520G

--


Antigen:
Cytokeratin 8/18

Classification:
Monoclonal

Conjugate:
DyLight 488

Formulation:
50 mM sodium borate with 0.05% sodium azide

Gene Symbols:
KRT8

Immunogen:
Cytoskeleton preparation from HeLa cells

Primary or Secondary:
Primary

Test Specificity:
Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). This monoclonal antibody recognizes all simple epithelia including glandular epithelium, for example thyroid, female breast, gastrointestinal tract, respiratory tract, and urogenital tract including transitional epithelium. All adenocarcinomas and most squamous carcinomas are positive but keratinizing squamous carcinomas are usually negative. This antibody is useful in demonstrating the presence of Paget cells; there is very little keratin 18 in the normal epidermis so only Paget cells are stained.

Content And Storage:
Store at 4°C in the dark.

Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
KRT8.18/1346

Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin

Gene Alias:
CARD2, CK8, CK-8, CYK8cytokeratin 8, Cytokeratin-8, K2C8, K8cytokeratin-8, keratin 8, keratin, type II cytoskeletal 8, keratin-8, KO, Type-II keratin Kb8

Host Species:
Mouse

Quantity:
0.1 mL

Gene ID (Entrez):
3856.0

Target Species:
Human

Isotype:
IgG1 κ