NBP275733
OCT2 Antibody (Oct2/2136) - Azide and BSA Free, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP275733-Each-of-1 | In Stock | ₹ 55,271.76 |
NBP275733 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
OCT2
Classification
Monoclonal
Concentration
0.2 mg/ml
Dilution
Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.
P09086
Gene Symbols
POU2F2
Immunogen
Recombinant fragment of human OCT2 protein (around aa 112-297) (exact sequence is proprietary) (Uniprot: P09086)
Purification Method
Protein A or G purified
Research Discipline
Cancer
Gene ID (Entrez)
5452.0
Target Species
Human
Form
Purified
Applications
Immunohistochemistry (Paraffin)
Clone
OCT2/2136
Conjugate
Unconjugated
Formulation
10 mM PBS with No Preservative
Gene Alias
homeobox protein, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, OCT2Oct-2, Octamer-binding protein 2, Octamer-binding transcription factor 2, OTF-2, OTF2POU domain class 2, transcription factor 2, POU class 2 homeobox 2, POU domain, class 2, transcription factor 2
Host Species
Mouse
Molecular Weight of Antigen
60 kDa
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
OCT2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. OCT2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of OCT2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of OCT2. Several studies of OCT2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for OCT2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.
Content And Storage
Store at 4°C.
Isotype
IgG1 κ
Description
- 44471 Monoclonal specifically detects 44471 in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.
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Antigen: OCT2
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P09086
Gene Symbols: POU2F2
Immunogen: Recombinant fragment of human OCT2 protein (around aa 112-297) (exact sequence is proprietary) (Uniprot: P09086)
Purification Method: Protein A or G purified
Research Discipline: Cancer
Gene ID (Entrez): 5452.0
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: OCT2/2136
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: homeobox protein, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, OCT2Oct-2, Octamer-binding protein 2, Octamer-binding transcription factor 2, OTF-2, OTF2POU domain class 2, transcription factor 2, POU class 2 homeobox 2, POU domain, class 2, transcription factor 2
Host Species: Mouse
Molecular Weight of Antigen: 60 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: OCT2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. OCT2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of OCT2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of OCT2. Several studies of OCT2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for OCT2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Antigen:
OCT2
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P09086
Gene Symbols:
POU2F2
Immunogen:
Recombinant fragment of human OCT2 protein (around aa 112-297) (exact sequence is proprietary) (Uniprot: P09086)
Purification Method:
Protein A or G purified
Research Discipline:
Cancer
Gene ID (Entrez):
5452.0
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
OCT2/2136
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
homeobox protein, Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2, OCT2Oct-2, Octamer-binding protein 2, Octamer-binding transcription factor 2, OTF-2, OTF2POU domain class 2, transcription factor 2, POU class 2 homeobox 2, POU domain, class 2, transcription factor 2
Host Species:
Mouse
Molecular Weight of Antigen:
60 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
OCT2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. OCT2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of OCT2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of OCT2. Several studies of OCT2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for OCT2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Antigen: Perforin
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P14222
Gene Symbols: PRF1
Immunogen: Recombinant human Perforin protein fragment (around aa 413-552) (exact sequence is proprietary) (Uniprot: P14222)
Purification Method: Protein A or G purified
Research Discipline: Adaptive Immunity, Apoptosis, Immunology, Innate Immunity
Gene ID (Entrez): 5551.0
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: PRF1/2468
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: Cytolysin, FLH2, HPLH2, HPLH2lymphocyte pore forming protein, Lymphocyte pore-forming protein, MGC65093, P1PFN1, perforin 1 (pore forming protein), perforin-1, PFPcytolysin
Host Species: Mouse
Molecular Weight of Antigen: 75 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis. Perforin has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. It is one of the main cytolytic proteins of cytolytic granules, and is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. The expression of perforin is reportedly upregulated in activated CD8+ T-cells, natural killer cells and some CD4+ T-cells.
Content And Storage: Store at 4°C.
Isotype: IgG2b κ
Antigen:
Perforin
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P14222
Gene Symbols:
PRF1
Immunogen:
Recombinant human Perforin protein fragment (around aa 413-552) (exact sequence is proprietary) (Uniprot: P14222)
Purification Method:
Protein A or G purified
Research Discipline:
Adaptive Immunity, Apoptosis, Immunology, Innate Immunity
Gene ID (Entrez):
5551.0
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
PRF1/2468
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
Cytolysin, FLH2, HPLH2, HPLH2lymphocyte pore forming protein, Lymphocyte pore-forming protein, MGC65093, P1PFN1, perforin 1 (pore forming protein), perforin-1, PFPcytolysin
Host Species:
Mouse
Molecular Weight of Antigen:
75 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis. Perforin has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. It is one of the main cytolytic proteins of cytolytic granules, and is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. The expression of perforin is reportedly upregulated in activated CD8+ T-cells, natural killer cells and some CD4+ T-cells.
Content And Storage:
Store at 4°C.
Isotype:
IgG2b κ
Antigen: StAR
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: __
Gene Symbols: STAR
Immunogen: Recombinant fragment (around aa 39-108) of human StAR protein (exact sequence is proprietary) (Uniprot: P49675)
Purification Method: Protein A or G purified
Research Discipline: Cancer
Gene ID (Entrez): 6770.0
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: STAR/2140
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: cholesterol trafficker, mitochondrial steroid acute regulatory protein, StAR, StARD1, STARD1StAR-related lipid transfer (START) domain containing 1, START domain containing 1, START domain-containing protein 1, steroid acute regulatory protein, steroidogenic acute regulator, steroidogenic acute regulatory protein, steroidogenic acute regulatory protein, mitochondrial
Host Species: Mouse
Molecular Weight of Antigen: 30 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.
Content And Storage: Store at 4°C.
Isotype: IgG2b κ
Antigen:
StAR
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
__
Gene Symbols:
STAR
Immunogen:
Recombinant fragment (around aa 39-108) of human StAR protein (exact sequence is proprietary) (Uniprot: P49675)
Purification Method:
Protein A or G purified
Research Discipline:
Cancer
Gene ID (Entrez):
6770.0
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
STAR/2140
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
cholesterol trafficker, mitochondrial steroid acute regulatory protein, StAR, StARD1, STARD1StAR-related lipid transfer (START) domain containing 1, START domain containing 1, START domain-containing protein 1, steroid acute regulatory protein, steroidogenic acute regulator, steroidogenic acute regulatory protein, steroidogenic acute regulatory protein, mitochondrial
Host Species:
Mouse
Molecular Weight of Antigen:
30 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.
Content And Storage:
Store at 4°C.
Isotype:
IgG2b κ
Antigen: StAR
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: __
Gene Symbols: STAR
Immunogen: Recombinant fragment (around aa 39-108) of human StAR protein (exact sequence is proprietary) (Uniprot: P49675)
Purification Method: Protein A or G purified
Research Discipline: Cancer
Gene ID (Entrez): 6770.0
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: STAR/2154
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: cholesterol trafficker, mitochondrial steroid acute regulatory protein, StAR, StARD1, STARD1StAR-related lipid transfer (START) domain containing 1, START domain containing 1, START domain-containing protein 1, steroid acute regulatory protein, steroidogenic acute regulator, steroidogenic acute regulatory protein, steroidogenic acute regulatory protein, mitochondrial
Host Species: Mouse
Molecular Weight of Antigen: 30 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Antigen:
StAR
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
__
Gene Symbols:
STAR
Immunogen:
Recombinant fragment (around aa 39-108) of human StAR protein (exact sequence is proprietary) (Uniprot: P49675)
Purification Method:
Protein A or G purified
Research Discipline:
Cancer
Gene ID (Entrez):
6770.0
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
STAR/2154
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
cholesterol trafficker, mitochondrial steroid acute regulatory protein, StAR, StARD1, STARD1StAR-related lipid transfer (START) domain containing 1, START domain containing 1, START domain-containing protein 1, steroid acute regulatory protein, steroidogenic acute regulator, steroidogenic acute regulatory protein, steroidogenic acute regulatory protein, mitochondrial
Host Species:
Mouse
Molecular Weight of Antigen:
30 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ