NBP275742

StAR Antibody (STAR/2154) - Azide and BSA Free, Novus Biologicals™

Manufacturer: Novus Biologicals

Select a Size

Pack Size SKU Availability Price
Each of 1 NBP275742-Each-of-1 In Stock ₹ 55,271.76

NBP275742 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

StAR

Classification

Monoclonal

Concentration

0.2 mg/ml

Dilution

Immunohistochemistry-Paraffin 1-2 ug/ml

Gene Alias

cholesterol trafficker, mitochondrial steroid acute regulatory protein, StAR, StARD1, STARD1StAR-related lipid transfer (START) domain containing 1, START domain containing 1, START domain-containing protein 1, steroid acute regulatory protein, steroidogenic acute regulator, steroidogenic acute regulatory protein, steroidogenic acute regulatory protein, mitochondrial

Host Species

Mouse

Molecular Weight of Antigen

30 kDa

Quantity

100 μg

Primary or Secondary

Primary

Test Specificity

Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.

Content And Storage

Store at 4°C.

Isotype

IgG1 κ

Applications

Immunohistochemistry (Paraffin)

Clone

STAR/2154

Conjugate

Unconjugated

Formulation

10 mM PBS with No Preservative

Gene Symbols

STAR

Immunogen

Recombinant fragment (around aa 39-108) of human StAR protein (exact sequence is proprietary) (Uniprot: P49675)

Purification Method

Protein A or G purified

Research Discipline

Cancer

Gene ID (Entrez)

6770.0

Target Species

Human

Form

Purified

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Description

  • StAR Monoclonal specifically detects StAR in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.

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Novus Biologicals

NBP275742

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Antigen:
StAR

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Immunohistochemistry-Paraffin 1-2 ug/ml

Gene Alias:
cholesterol trafficker, mitochondrial steroid acute regulatory protein, StAR, StARD1, STARD1StAR-related lipid transfer (START) domain containing 1, START domain containing 1, START domain-containing protein 1, steroid acute regulatory protein, steroidogenic acute regulator, steroidogenic acute regulatory protein, steroidogenic acute regulatory protein, mitochondrial

Host Species:
Mouse

Molecular Weight of Antigen:
30 kDa

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas.

Content And Storage:
Store at 4°C.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
STAR/2154

Conjugate:
Unconjugated

Formulation:
10 mM PBS with No Preservative

Gene Symbols:
STAR

Immunogen:
Recombinant fragment (around aa 39-108) of human StAR protein (exact sequence is proprietary) (Uniprot: P49675)

Purification Method:
Protein A or G purified

Research Discipline:
Cancer

Gene ID (Entrez):
6770.0

Target Species:
Human

Form:
Purified

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Novus Biologicals

NBP275744

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Antigen:
TROP-2

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Western Blot 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml

Gene Alias:
Cell surface glycoprotein Trop-2, EGP1, EGP-1, epithelial glycoprotein-1, GA733-1GP50, gastrointestinal tumor-associated antigen GA7331, M1S1cell surface glycoprotein TROP2, Membrane component chromosome 1 surface marker 1, membrane component, chromosome 1, surface marker 1, Pancreatic carcinoma marker protein GA733-1, pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733, TROP2GA7331, tumor-associated calcium signal transducer 2

Host Species:
Mouse

Molecular Weight of Antigen:
40 kDa

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
TROP-2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.

Content And Storage:
Store at 4°C.

Isotype:
IgG2b κ

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Clone:
TACSTD2/2151

Conjugate:
Unconjugated

Formulation:
10 mM PBS with No Preservative

Gene Symbols:
TACSTD2

Immunogen:
Recombinant fragment of human TROP-2 protein (around aa 31-274) (exact sequence is proprietary) (Uniprot: P09758 )

Purification Method:
Protein A or G purified

Research Discipline:
Signal Transduction

Gene ID (Entrez):
4070.0

Target Species:
Human

Form:
Purified

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Novus Biologicals

NBP275749

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Antigen:
Bcl-6

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml

Gene Alias:
B-cell CLL/lymphoma 6, B-cell lymphoma 6 protein transcript, BCL-5, BCL5B-cell lymphoma 5 protein, BCL-6, BCL6A, cys-his2 zinc finger transcription factor, LAZ3ZBTB27B-cell lymphoma 6 protein, lymphoma-associated zinc finger gene on chromosome 3, Protein LAZ-3, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51ZNF51, zinc finger transcription factor BCL6S

Host Species:
Mouse

Molecular Weight of Antigen:
95 kDa

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ('LH') cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.

Content And Storage:
Store at 4°C.

Isotype:
IgG1 κ

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
BCL6/1982

Conjugate:
Unconjugated

Formulation:
10 mM PBS with No Preservative

Gene Symbols:
BCL6

Immunogen:
Recombinant human bcl-6 protein fragment (around aa256-389) (exact sequence is proprietary) (Uniprot: P41182)

Purification Method:
Protein A or G purified

Research Discipline:
Cancer, Cell Cycle and Replication, Tumor Suppressors

Gene ID (Entrez):
604.0

Target Species:
Human

Form:
Purified

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Novus Biologicals

NBP275750

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Antigen:
TCL1A

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Immunohistochemistry-Paraffin 1-2 ug/ml

Gene Alias:
Oncogene TCL1, Oncogene TCL-1, Protein p14 TCL1, T-cell leukemia/lymphoma 1A, T-cell lymphoma-1, T-cell lymphoma-1A, TCL1T-cell leukemia/lymphoma protein 1A

Host Species:
Mouse

Molecular Weight of Antigen:
14 kDa

Quantity:
100 μg

Primary or Secondary:
Primary

Test Specificity:
T-cell leukemia/Lymphoma Protein 1A (TCL1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.

Content And Storage:
Store at 4°C.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
TCL1/2078

Conjugate:
Unconjugated

Formulation:
10 mM PBS with No Preservative

Gene Symbols:
TCL1A

Immunogen:
Recombinant human TCL1A protein fragment (around aa 2-109) (exact sequence is proprietary) (Uniprot: P56279)

Purification Method:
Protein A or G purified

Research Discipline:
__

Gene ID (Entrez):
8115.0

Target Species:
Human

Form:
Purified