NBP275744
TROP-2 Antibody (TACSTD2/2151) - Azide and BSA Free, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP275744-Each-of-1 | In Stock | ₹ 55,271.76 |
NBP275744 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
TROP-2
Classification
Monoclonal
Concentration
0.2 mg/ml
Dilution
Western Blot 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.
P09758
Gene Symbols
TACSTD2
Immunogen
Recombinant fragment of human TROP-2 protein (around aa 31-274) (exact sequence is proprietary) (Uniprot: P09758 )
Purification Method
Protein A or G purified
Research Discipline
Signal Transduction
Gene ID (Entrez)
4070.0
Target Species
Human
Form
Purified
Applications
Western Blot, Immunohistochemistry (Paraffin)
Clone
TACSTD2/2151
Conjugate
Unconjugated
Formulation
10 mM PBS with No Preservative
Gene Alias
Cell surface glycoprotein Trop-2, EGP1, EGP-1, epithelial glycoprotein-1, GA733-1GP50, gastrointestinal tumor-associated antigen GA7331, M1S1cell surface glycoprotein TROP2, Membrane component chromosome 1 surface marker 1, membrane component, chromosome 1, surface marker 1, Pancreatic carcinoma marker protein GA733-1, pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733, TROP2GA7331, tumor-associated calcium signal transducer 2
Host Species
Mouse
Molecular Weight of Antigen
40 kDa
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
TROP-2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.
Content And Storage
Store at 4°C.
Isotype
IgG2b κ
Description
- TROP-2 Monoclonal specifically detects TROP-2 in Human samples
- It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.
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Antigen: TROP-2
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Western Blot 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P09758
Gene Symbols: TACSTD2
Immunogen: Recombinant fragment of human TROP-2 protein (around aa 31-274) (exact sequence is proprietary) (Uniprot: P09758 )
Purification Method: Protein A or G purified
Research Discipline: Signal Transduction
Gene ID (Entrez): 4070.0
Target Species: Human
Form: Purified
Applications: Western Blot, Immunohistochemistry (Paraffin)
Clone: TACSTD2/2151
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: Cell surface glycoprotein Trop-2, EGP1, EGP-1, epithelial glycoprotein-1, GA733-1GP50, gastrointestinal tumor-associated antigen GA7331, M1S1cell surface glycoprotein TROP2, Membrane component chromosome 1 surface marker 1, membrane component, chromosome 1, surface marker 1, Pancreatic carcinoma marker protein GA733-1, pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733, TROP2GA7331, tumor-associated calcium signal transducer 2
Host Species: Mouse
Molecular Weight of Antigen: 40 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: TROP-2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.
Content And Storage: Store at 4°C.
Isotype: IgG2b κ
Antigen:
TROP-2
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Western Blot 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P09758
Gene Symbols:
TACSTD2
Immunogen:
Recombinant fragment of human TROP-2 protein (around aa 31-274) (exact sequence is proprietary) (Uniprot: P09758 )
Purification Method:
Protein A or G purified
Research Discipline:
Signal Transduction
Gene ID (Entrez):
4070.0
Target Species:
Human
Form:
Purified
Applications:
Western Blot, Immunohistochemistry (Paraffin)
Clone:
TACSTD2/2151
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
Cell surface glycoprotein Trop-2, EGP1, EGP-1, epithelial glycoprotein-1, GA733-1GP50, gastrointestinal tumor-associated antigen GA7331, M1S1cell surface glycoprotein TROP2, Membrane component chromosome 1 surface marker 1, membrane component, chromosome 1, surface marker 1, Pancreatic carcinoma marker protein GA733-1, pancreatic carcinoma marker protein GA7331,40kD glycoprotein, identified by monoclonal GA733, TROP2GA7331, tumor-associated calcium signal transducer 2
Host Species:
Mouse
Molecular Weight of Antigen:
40 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
TROP-2 is a cell surface glycoprotein receptor. It is a single pass type I membrane protein containing one thyroglobulin type-1 domain, an epidermal growth factor-like repeat, a phosphatidylinositol binding site and tyrosine phosphorylation sites near the C-terminus. It plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. It is also highly expressed in several types of tumors and is involved in regulating the growth of carcinoma cells.
Content And Storage:
Store at 4°C.
Isotype:
IgG2b κ
Antigen: Bcl-6
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P41182
Gene Symbols: BCL6
Immunogen: Recombinant human bcl-6 protein fragment (around aa256-389) (exact sequence is proprietary) (Uniprot: P41182)
Purification Method: Protein A or G purified
Research Discipline: Cancer, Cell Cycle and Replication, Tumor Suppressors
Gene ID (Entrez): 604.0
Target Species: Human
Form: Purified
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: BCL6/1982
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: B-cell CLL/lymphoma 6, B-cell lymphoma 6 protein transcript, BCL-5, BCL5B-cell lymphoma 5 protein, BCL-6, BCL6A, cys-his2 zinc finger transcription factor, LAZ3ZBTB27B-cell lymphoma 6 protein, lymphoma-associated zinc finger gene on chromosome 3, Protein LAZ-3, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51ZNF51, zinc finger transcription factor BCL6S
Host Species: Mouse
Molecular Weight of Antigen: 95 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ('LH') cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Antigen:
Bcl-6
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P41182
Gene Symbols:
BCL6
Immunogen:
Recombinant human bcl-6 protein fragment (around aa256-389) (exact sequence is proprietary) (Uniprot: P41182)
Purification Method:
Protein A or G purified
Research Discipline:
Cancer, Cell Cycle and Replication, Tumor Suppressors
Gene ID (Entrez):
604.0
Target Species:
Human
Form:
Purified
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
BCL6/1982
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
B-cell CLL/lymphoma 6, B-cell lymphoma 6 protein transcript, BCL-5, BCL5B-cell lymphoma 5 protein, BCL-6, BCL6A, cys-his2 zinc finger transcription factor, LAZ3ZBTB27B-cell lymphoma 6 protein, lymphoma-associated zinc finger gene on chromosome 3, Protein LAZ-3, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51ZNF51, zinc finger transcription factor BCL6S
Host Species:
Mouse
Molecular Weight of Antigen:
95 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ('LH') cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Antigen: TCL1A
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P56279, P56279
Gene Symbols: TCL1A
Immunogen: Recombinant human TCL1A protein fragment (around aa 2-109) (exact sequence is proprietary) (Uniprot: P56279)
Purification Method: Protein A or G purified
Research Discipline: __
Gene ID (Entrez): 8115.0
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: TCL1/2078
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: Oncogene TCL1, Oncogene TCL-1, Protein p14 TCL1, T-cell leukemia/lymphoma 1A, T-cell lymphoma-1, T-cell lymphoma-1A, TCL1T-cell leukemia/lymphoma protein 1A
Host Species: Mouse
Molecular Weight of Antigen: 14 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: T-cell leukemia/Lymphoma Protein 1A (TCL1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Antigen:
TCL1A
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P56279, P56279
Gene Symbols:
TCL1A
Immunogen:
Recombinant human TCL1A protein fragment (around aa 2-109) (exact sequence is proprietary) (Uniprot: P56279)
Purification Method:
Protein A or G purified
Research Discipline:
__
Gene ID (Entrez):
8115.0
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
TCL1/2078
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
Oncogene TCL1, Oncogene TCL-1, Protein p14 TCL1, T-cell leukemia/lymphoma 1A, T-cell lymphoma-1, T-cell lymphoma-1A, TCL1T-cell leukemia/lymphoma protein 1A
Host Species:
Mouse
Molecular Weight of Antigen:
14 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
T-cell leukemia/Lymphoma Protein 1A (TCL1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Antigen: CDX2
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Western Blot 0.5-1.0 ug/ml, Immunoprecipitation 2-4 ug/mg protein, Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.: Q99626, Q99626
Gene Symbols: CDX2
Immunogen: Recombinant human full-length CDX2 protein (Uniprot: Q99626)
Purification Method: Protein A or G purified
Research Discipline: Cancer, Chromatin Research, DNA Repair, Growth and Development, Transcription Factors and Regulators
Gene ID (Entrez): 1045.0
Target Species: Human
Form: Purified
Applications: Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
Clone: PCRP-CDX2-1A3
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: caudal type homeo box transcription factor 2, caudal type homeobox 2, Caudal-type homeobox protein 2, CDX-3, CDX3caudal type homeobox transcription factor 2, homeobox protein CDX-2
Host Species: Mouse
Molecular Weight of Antigen: 40 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: The specificity of this monoclonal antibody to its intended target was validated by HuProtTMArray, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Antigen:
CDX2
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Western Blot 0.5-1.0 ug/ml, Immunoprecipitation 2-4 ug/mg protein, Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.:
Q99626, Q99626
Gene Symbols:
CDX2
Immunogen:
Recombinant human full-length CDX2 protein (Uniprot: Q99626)
Purification Method:
Protein A or G purified
Research Discipline:
Cancer, Chromatin Research, DNA Repair, Growth and Development, Transcription Factors and Regulators
Gene ID (Entrez):
1045.0
Target Species:
Human
Form:
Purified
Applications:
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
Clone:
PCRP-CDX2-1A3
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
caudal type homeo box transcription factor 2, caudal type homeobox 2, Caudal-type homeobox protein 2, CDX-3, CDX3caudal type homeobox transcription factor 2, homeobox protein CDX-2
Host Species:
Mouse
Molecular Weight of Antigen:
40 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
The specificity of this monoclonal antibody to its intended target was validated by HuProtTMArray, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ