NBP275749
Bcl-6 Antibody (BCL6/1982) - Azide and BSA Free, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP275749-Each-of-1 | In Stock | ₹ 55,271.76 |
NBP275749 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
Bcl-6
Classification
Monoclonal
Concentration
0.2 mg/ml
Dilution
ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.
P41182
Gene Symbols
BCL6
Immunogen
Recombinant human bcl-6 protein fragment (around aa256-389) (exact sequence is proprietary) (Uniprot: P41182)
Purification Method
Protein A or G purified
Research Discipline
Cancer, Cell Cycle and Replication, Tumor Suppressors
Gene ID (Entrez)
604.0
Target Species
Human
Form
Purified
Applications
ELISA, Immunohistochemistry (Paraffin)
Clone
BCL6/1982
Conjugate
Unconjugated
Formulation
10 mM PBS with No Preservative
Gene Alias
B-cell CLL/lymphoma 6, B-cell lymphoma 6 protein transcript, BCL-5, BCL5B-cell lymphoma 5 protein, BCL-6, BCL6A, cys-his2 zinc finger transcription factor, LAZ3ZBTB27B-cell lymphoma 6 protein, lymphoma-associated zinc finger gene on chromosome 3, Protein LAZ-3, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51ZNF51, zinc finger transcription factor BCL6S
Host Species
Mouse
Molecular Weight of Antigen
95 kDa
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ('LH') cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
Content And Storage
Store at 4°C.
Isotype
IgG1 κ
Related Products
Description
- Bcl-6 Monoclonal specifically detects Bcl-6 in Human samples
- It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.
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Antigen: Bcl-6
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P41182
Gene Symbols: BCL6
Immunogen: Recombinant human bcl-6 protein fragment (around aa256-389) (exact sequence is proprietary) (Uniprot: P41182)
Purification Method: Protein A or G purified
Research Discipline: Cancer, Cell Cycle and Replication, Tumor Suppressors
Gene ID (Entrez): 604.0
Target Species: Human
Form: Purified
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: BCL6/1982
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: B-cell CLL/lymphoma 6, B-cell lymphoma 6 protein transcript, BCL-5, BCL5B-cell lymphoma 5 protein, BCL-6, BCL6A, cys-his2 zinc finger transcription factor, LAZ3ZBTB27B-cell lymphoma 6 protein, lymphoma-associated zinc finger gene on chromosome 3, Protein LAZ-3, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51ZNF51, zinc finger transcription factor BCL6S
Host Species: Mouse
Molecular Weight of Antigen: 95 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ('LH') cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Antigen:
Bcl-6
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P41182
Gene Symbols:
BCL6
Immunogen:
Recombinant human bcl-6 protein fragment (around aa256-389) (exact sequence is proprietary) (Uniprot: P41182)
Purification Method:
Protein A or G purified
Research Discipline:
Cancer, Cell Cycle and Replication, Tumor Suppressors
Gene ID (Entrez):
604.0
Target Species:
Human
Form:
Purified
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
BCL6/1982
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
B-cell CLL/lymphoma 6, B-cell lymphoma 6 protein transcript, BCL-5, BCL5B-cell lymphoma 5 protein, BCL-6, BCL6A, cys-his2 zinc finger transcription factor, LAZ3ZBTB27B-cell lymphoma 6 protein, lymphoma-associated zinc finger gene on chromosome 3, Protein LAZ-3, Zinc finger and BTB domain-containing protein 27, Zinc finger protein 51ZNF51, zinc finger transcription factor BCL6S
Host Species:
Mouse
Molecular Weight of Antigen:
95 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ('LH') cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Antigen: TCL1A
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P56279, P56279
Gene Symbols: TCL1A
Immunogen: Recombinant human TCL1A protein fragment (around aa 2-109) (exact sequence is proprietary) (Uniprot: P56279)
Purification Method: Protein A or G purified
Research Discipline: __
Gene ID (Entrez): 8115.0
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: TCL1/2078
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: Oncogene TCL1, Oncogene TCL-1, Protein p14 TCL1, T-cell leukemia/lymphoma 1A, T-cell lymphoma-1, T-cell lymphoma-1A, TCL1T-cell leukemia/lymphoma protein 1A
Host Species: Mouse
Molecular Weight of Antigen: 14 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: T-cell leukemia/Lymphoma Protein 1A (TCL1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Antigen:
TCL1A
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P56279, P56279
Gene Symbols:
TCL1A
Immunogen:
Recombinant human TCL1A protein fragment (around aa 2-109) (exact sequence is proprietary) (Uniprot: P56279)
Purification Method:
Protein A or G purified
Research Discipline:
__
Gene ID (Entrez):
8115.0
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
TCL1/2078
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
Oncogene TCL1, Oncogene TCL-1, Protein p14 TCL1, T-cell leukemia/lymphoma 1A, T-cell lymphoma-1, T-cell lymphoma-1A, TCL1T-cell leukemia/lymphoma protein 1A
Host Species:
Mouse
Molecular Weight of Antigen:
14 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
T-cell leukemia/Lymphoma Protein 1A (TCL1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Antigen: CDX2
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Western Blot 0.5-1.0 ug/ml, Immunoprecipitation 2-4 ug/mg protein, Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.: Q99626, Q99626
Gene Symbols: CDX2
Immunogen: Recombinant human full-length CDX2 protein (Uniprot: Q99626)
Purification Method: Protein A or G purified
Research Discipline: Cancer, Chromatin Research, DNA Repair, Growth and Development, Transcription Factors and Regulators
Gene ID (Entrez): 1045.0
Target Species: Human
Form: Purified
Applications: Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
Clone: PCRP-CDX2-1A3
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: caudal type homeo box transcription factor 2, caudal type homeobox 2, Caudal-type homeobox protein 2, CDX-3, CDX3caudal type homeobox transcription factor 2, homeobox protein CDX-2
Host Species: Mouse
Molecular Weight of Antigen: 40 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: The specificity of this monoclonal antibody to its intended target was validated by HuProtTMArray, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Antigen:
CDX2
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Western Blot 0.5-1.0 ug/ml, Immunoprecipitation 2-4 ug/mg protein, Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.:
Q99626, Q99626
Gene Symbols:
CDX2
Immunogen:
Recombinant human full-length CDX2 protein (Uniprot: Q99626)
Purification Method:
Protein A or G purified
Research Discipline:
Cancer, Chromatin Research, DNA Repair, Growth and Development, Transcription Factors and Regulators
Gene ID (Entrez):
1045.0
Target Species:
Human
Form:
Purified
Applications:
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
Clone:
PCRP-CDX2-1A3
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
caudal type homeo box transcription factor 2, caudal type homeobox 2, Caudal-type homeobox protein 2, CDX-3, CDX3caudal type homeobox transcription factor 2, homeobox protein CDX-2
Host Species:
Mouse
Molecular Weight of Antigen:
40 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
The specificity of this monoclonal antibody to its intended target was validated by HuProtTMArray, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Antigen: AIF-1/Iba1
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P55008
Gene Symbols: AIF1
Immunogen: Purified recombinant human AIF-1/Iba1 protein (around aa 1-146) (exact sequence is proprietary) (Uniprot: P55008)
Purification Method: Protein A or G purified
Research Discipline: Autoimmune Diseases, Cancer, Cell Biology, Cell Cycle and Replication, Immunology, Inflammation, Lipid and Metabolism, Microglia Markers, Neuroscience
Gene ID (Entrez): 199.0
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: rAIF1/1909
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: AIF-1, allograft inflammatory factor 1, G1, IBA1, IbaI, interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, IRT1, IRT-1, Protein G1
Host Species: Mouse
Molecular Weight of Antigen: 16.7 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Antigen:
AIF-1/Iba1
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P55008
Gene Symbols:
AIF1
Immunogen:
Purified recombinant human AIF-1/Iba1 protein (around aa 1-146) (exact sequence is proprietary) (Uniprot: P55008)
Purification Method:
Protein A or G purified
Research Discipline:
Autoimmune Diseases, Cancer, Cell Biology, Cell Cycle and Replication, Immunology, Inflammation, Lipid and Metabolism, Microglia Markers, Neuroscience
Gene ID (Entrez):
199.0
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
rAIF1/1909
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
AIF-1, allograft inflammatory factor 1, G1, IBA1, IbaI, interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, IRT1, IRT-1, Protein G1
Host Species:
Mouse
Molecular Weight of Antigen:
16.7 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ