NBP275759
CDX2 Antibody (PCRP-CDX2-1A3) - Azide and BSA Free, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP275759-Each-of-1 | In Stock | ₹ 55,271.76 |
NBP275759 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
CDX2
Classification
Monoclonal
Concentration
0.2 mg/ml
Dilution
Western Blot 0.5-1.0 ug/ml, Immunoprecipitation 2-4 ug/mg protein, Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.
Q99626, Q99626
Gene Symbols
CDX2
Immunogen
Recombinant human full-length CDX2 protein (Uniprot: Q99626)
Purification Method
Protein A or G purified
Research Discipline
Cancer, Chromatin Research, DNA Repair, Growth and Development, Transcription Factors and Regulators
Gene ID (Entrez)
1045.0
Target Species
Human
Form
Purified
Applications
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
Clone
PCRP-CDX2-1A3
Conjugate
Unconjugated
Formulation
10 mM PBS with No Preservative
Gene Alias
caudal type homeo box transcription factor 2, caudal type homeobox 2, Caudal-type homeobox protein 2, CDX-3, CDX3caudal type homeobox transcription factor 2, homeobox protein CDX-2
Host Species
Mouse
Molecular Weight of Antigen
40 kDa
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
The specificity of this monoclonal antibody to its intended target was validated by HuProtTMArray, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
Content And Storage
Store at 4°C.
Isotype
IgG1 κ
Description
- CDX2 Monoclonal specifically detects CDX2 in Human samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Microarray, Protein Array.
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Antigen: CDX2
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Western Blot 0.5-1.0 ug/ml, Immunoprecipitation 2-4 ug/mg protein, Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.: Q99626, Q99626
Gene Symbols: CDX2
Immunogen: Recombinant human full-length CDX2 protein (Uniprot: Q99626)
Purification Method: Protein A or G purified
Research Discipline: Cancer, Chromatin Research, DNA Repair, Growth and Development, Transcription Factors and Regulators
Gene ID (Entrez): 1045.0
Target Species: Human
Form: Purified
Applications: Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
Clone: PCRP-CDX2-1A3
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: caudal type homeo box transcription factor 2, caudal type homeobox 2, Caudal-type homeobox protein 2, CDX-3, CDX3caudal type homeobox transcription factor 2, homeobox protein CDX-2
Host Species: Mouse
Molecular Weight of Antigen: 40 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: The specificity of this monoclonal antibody to its intended target was validated by HuProtTMArray, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Antigen:
CDX2
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Western Blot 0.5-1.0 ug/ml, Immunoprecipitation 2-4 ug/mg protein, Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.:
Q99626, Q99626
Gene Symbols:
CDX2
Immunogen:
Recombinant human full-length CDX2 protein (Uniprot: Q99626)
Purification Method:
Protein A or G purified
Research Discipline:
Cancer, Chromatin Research, DNA Repair, Growth and Development, Transcription Factors and Regulators
Gene ID (Entrez):
1045.0
Target Species:
Human
Form:
Purified
Applications:
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)
Clone:
PCRP-CDX2-1A3
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
caudal type homeo box transcription factor 2, caudal type homeobox 2, Caudal-type homeobox protein 2, CDX-3, CDX3caudal type homeobox transcription factor 2, homeobox protein CDX-2
Host Species:
Mouse
Molecular Weight of Antigen:
40 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
The specificity of this monoclonal antibody to its intended target was validated by HuProtTMArray, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Antigen: AIF-1/Iba1
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P55008
Gene Symbols: AIF1
Immunogen: Purified recombinant human AIF-1/Iba1 protein (around aa 1-146) (exact sequence is proprietary) (Uniprot: P55008)
Purification Method: Protein A or G purified
Research Discipline: Autoimmune Diseases, Cancer, Cell Biology, Cell Cycle and Replication, Immunology, Inflammation, Lipid and Metabolism, Microglia Markers, Neuroscience
Gene ID (Entrez): 199.0
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: rAIF1/1909
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: AIF-1, allograft inflammatory factor 1, G1, IBA1, IbaI, interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, IRT1, IRT-1, Protein G1
Host Species: Mouse
Molecular Weight of Antigen: 16.7 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Antigen:
AIF-1/Iba1
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P55008
Gene Symbols:
AIF1
Immunogen:
Purified recombinant human AIF-1/Iba1 protein (around aa 1-146) (exact sequence is proprietary) (Uniprot: P55008)
Purification Method:
Protein A or G purified
Research Discipline:
Autoimmune Diseases, Cancer, Cell Biology, Cell Cycle and Replication, Immunology, Inflammation, Lipid and Metabolism, Microglia Markers, Neuroscience
Gene ID (Entrez):
199.0
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
rAIF1/1909
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
AIF-1, allograft inflammatory factor 1, G1, IBA1, IbaI, interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, IRT1, IRT-1, Protein G1
Host Species:
Mouse
Molecular Weight of Antigen:
16.7 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Antigen: Bcl-2
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Western Blot 0.5 - 1 μg/mL, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1 - 2 μg/mL, Immunohistochemistry-Paraffin 0.5 - 1 μg/mL, Protein Array
Gene Accession No.: P10415, P10415
Gene Symbols: BCL2
Immunogen: Recombinant full-length human bcl-2 protein (Uniprot: P10415)
Purification Method: Protein A or G purified
Research Discipline: Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Tumor Suppressors
Gene ID (Entrez): 596.0
Target Species: Human
Form: Purified
Applications: Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array
Clone: BCL2/2210R
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2
Host Species: Rabbit
Molecular Weight of Antigen: __
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.
Content And Storage: Store at 4°C.
Isotype: IgG
Antigen:
Bcl-2
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Western Blot 0.5 - 1 μg/mL, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1 - 2 μg/mL, Immunohistochemistry-Paraffin 0.5 - 1 μg/mL, Protein Array
Gene Accession No.:
P10415, P10415
Gene Symbols:
BCL2
Immunogen:
Recombinant full-length human bcl-2 protein (Uniprot: P10415)
Purification Method:
Protein A or G purified
Research Discipline:
Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Tumor Suppressors
Gene ID (Entrez):
596.0
Target Species:
Human
Form:
Purified
Applications:
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array
Clone:
BCL2/2210R
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2
Host Species:
Rabbit
Molecular Weight of Antigen:
__
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.
Content And Storage:
Store at 4°C.
Isotype:
IgG
Antigen: PU.1/Spi-1
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Western Blot 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P17947
Gene Symbols: SPI1
Immunogen: Recombinant fragment (around aa 16-170) of human PU.1/Spi-1 protein (Exact sequence is proprietary) (Uniprot: P17947 )
Purification Method: Protein A or G purified
Research Discipline: Innate Immunity
Gene ID (Entrez): 6688.0
Target Species: Human
Form: Purified
Applications: Western Blot, Immunohistochemistry (Paraffin)
Clone: PU1/2146
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: hematopoietic transcription factor PU.1, OF, PU.1, SFPI131 kDa transforming protein, SPI-1, SPI-1 proto-oncogene, SPI-A, spleen focus forming virus (SFFV) proviral integration oncogene spi1,31 kDa-transforming protein, transcription factor PU.1
Host Species: Mouse
Molecular Weight of Antigen: 40 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: PU.1 is a member of the ETS family of transcription factors and is important for normal B-cell development. It is expressed in the myeloid lineage and in immature as well as mature B-lymphocytes, with the exception of plasma cells. PU.1 is expressed in germinal center B-cells and mantle B-cells. Various lymphomas are also positive for this marker. It is essential during early B-cell differentiation. The absence of PU.1 results in total block of B-cell development at the pre-pro stage. PU.1 plays a key role in normal myeloid differentiation, and regulates the expression of immunoglobulin and other genes that are important for B-cell development.
Content And Storage: Store at 4°C.
Isotype: IgG2b κ
Antigen:
PU.1/Spi-1
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Western Blot 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P17947
Gene Symbols:
SPI1
Immunogen:
Recombinant fragment (around aa 16-170) of human PU.1/Spi-1 protein (Exact sequence is proprietary) (Uniprot: P17947 )
Purification Method:
Protein A or G purified
Research Discipline:
Innate Immunity
Gene ID (Entrez):
6688.0
Target Species:
Human
Form:
Purified
Applications:
Western Blot, Immunohistochemistry (Paraffin)
Clone:
PU1/2146
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
hematopoietic transcription factor PU.1, OF, PU.1, SFPI131 kDa transforming protein, SPI-1, SPI-1 proto-oncogene, SPI-A, spleen focus forming virus (SFFV) proviral integration oncogene spi1,31 kDa-transforming protein, transcription factor PU.1
Host Species:
Mouse
Molecular Weight of Antigen:
40 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
PU.1 is a member of the ETS family of transcription factors and is important for normal B-cell development. It is expressed in the myeloid lineage and in immature as well as mature B-lymphocytes, with the exception of plasma cells. PU.1 is expressed in germinal center B-cells and mantle B-cells. Various lymphomas are also positive for this marker. It is essential during early B-cell differentiation. The absence of PU.1 results in total block of B-cell development at the pre-pro stage. PU.1 plays a key role in normal myeloid differentiation, and regulates the expression of immunoglobulin and other genes that are important for B-cell development.
Content And Storage:
Store at 4°C.
Isotype:
IgG2b κ