NBP275764
Bcl-2 Antibody (BCL2/2210R) - Azide and BSA Free, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP275764-Each-of-1 | In Stock | ₹ 56,298.48 |
NBP275764 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 56,298.48
GST (18%): ₹ 10,133.726
Total Price: ₹ 66,432.206
Antigen
Bcl-2
Classification
Monoclonal
Concentration
0.2 mg/ml
Dilution
Western Blot 0.5 - 1 μg/mL, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1 - 2 μg/mL, Immunohistochemistry-Paraffin 0.5 - 1 μg/mL, Protein Array
Gene Accession No.
P10415, P10415
Gene Symbols
BCL2
Immunogen
Recombinant full-length human bcl-2 protein (Uniprot: P10415)
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.
Content And Storage
Store at 4°C.
Isotype
IgG
Applications
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array
Clone
BCL2/2210R
Conjugate
Unconjugated
Formulation
10 mM PBS with No Preservative
Gene Alias
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2
Host Species
Rabbit
Purification Method
Protein A or G purified
Research Discipline
Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Tumor Suppressors
Gene ID (Entrez)
596.0
Target Species
Human
Form
Purified
Related Products
Description
- Bcl-2 Monoclonal specifically detects Bcl-2 in Human samples
- It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.
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Antigen: Bcl-2
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Western Blot 0.5 - 1 μg/mL, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1 - 2 μg/mL, Immunohistochemistry-Paraffin 0.5 - 1 μg/mL, Protein Array
Gene Accession No.: P10415, P10415
Gene Symbols: BCL2
Immunogen: Recombinant full-length human bcl-2 protein (Uniprot: P10415)
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.
Content And Storage: Store at 4°C.
Isotype: IgG
Applications: Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array
Clone: BCL2/2210R
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2
Host Species: Rabbit
Purification Method: Protein A or G purified
Research Discipline: Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Tumor Suppressors
Gene ID (Entrez): 596.0
Target Species: Human
Form: Purified
Antigen:
Bcl-2
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Western Blot 0.5 - 1 μg/mL, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1 - 2 μg/mL, Immunohistochemistry-Paraffin 0.5 - 1 μg/mL, Protein Array
Gene Accession No.:
P10415, P10415
Gene Symbols:
BCL2
Immunogen:
Recombinant full-length human bcl-2 protein (Uniprot: P10415)
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.
Content And Storage:
Store at 4°C.
Isotype:
IgG
Applications:
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array
Clone:
BCL2/2210R
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2
Host Species:
Rabbit
Purification Method:
Protein A or G purified
Research Discipline:
Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Tumor Suppressors
Gene ID (Entrez):
596.0
Target Species:
Human
Form:
Purified
Antigen: PU.1/Spi-1
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Western Blot 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P17947
Gene Symbols: SPI1
Immunogen: Recombinant fragment (around aa 16-170) of human PU.1/Spi-1 protein (Exact sequence is proprietary) (Uniprot: P17947 )
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: PU.1 is a member of the ETS family of transcription factors and is important for normal B-cell development. It is expressed in the myeloid lineage and in immature as well as mature B-lymphocytes, with the exception of plasma cells. PU.1 is expressed in germinal center B-cells and mantle B-cells. Various lymphomas are also positive for this marker. It is essential during early B-cell differentiation. The absence of PU.1 results in total block of B-cell development at the pre-pro stage. PU.1 plays a key role in normal myeloid differentiation, and regulates the expression of immunoglobulin and other genes that are important for B-cell development.
Content And Storage: Store at 4°C.
Isotype: IgG2b κ
Applications: Western Blot, Immunohistochemistry (Paraffin)
Clone: PU1/2146
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: hematopoietic transcription factor PU.1, OF, PU.1, SFPI131 kDa transforming protein, SPI-1, SPI-1 proto-oncogene, SPI-A, spleen focus forming virus (SFFV) proviral integration oncogene spi1,31 kDa-transforming protein, transcription factor PU.1
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Innate Immunity
Gene ID (Entrez): 6688.0
Target Species: Human
Form: Purified
Antigen:
PU.1/Spi-1
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Western Blot 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P17947
Gene Symbols:
SPI1
Immunogen:
Recombinant fragment (around aa 16-170) of human PU.1/Spi-1 protein (Exact sequence is proprietary) (Uniprot: P17947 )
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
PU.1 is a member of the ETS family of transcription factors and is important for normal B-cell development. It is expressed in the myeloid lineage and in immature as well as mature B-lymphocytes, with the exception of plasma cells. PU.1 is expressed in germinal center B-cells and mantle B-cells. Various lymphomas are also positive for this marker. It is essential during early B-cell differentiation. The absence of PU.1 results in total block of B-cell development at the pre-pro stage. PU.1 plays a key role in normal myeloid differentiation, and regulates the expression of immunoglobulin and other genes that are important for B-cell development.
Content And Storage:
Store at 4°C.
Isotype:
IgG2b κ
Applications:
Western Blot, Immunohistochemistry (Paraffin)
Clone:
PU1/2146
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
hematopoietic transcription factor PU.1, OF, PU.1, SFPI131 kDa transforming protein, SPI-1, SPI-1 proto-oncogene, SPI-A, spleen focus forming virus (SFFV) proviral integration oncogene spi1,31 kDa-transforming protein, transcription factor PU.1
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Innate Immunity
Gene ID (Entrez):
6688.0
Target Species:
Human
Form:
Purified
Antigen: Cytokeratin 1/10
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1 ug/ml, Immunohistochemistry-Paraffin 0.1-0.2 ug/ml
Gene Accession No.: P13645
Gene Symbols: KRT10
Immunogen: Recombinant human full-length Cytokeratin 10 protein (Uniprot: P13645)
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
Content And Storage: Store at 4°C.
Isotype: IgG
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: KRT10/1990R
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: 67 kDa cytokeratin, CK 1, CK 10, CK1, CK10, Cytokeratin 10, Cytokeratin1, Cytokeratin10, EHK 1, EHK1, EPPK, Hair Alpha Protein, K1, k10, Keratin 1, Keratin 1 (epidermolytic hyperkeratosis), Keratin 10, Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris), Keratin type I cytoskeletal 10, Keratin Type II Cytoskeletal 1, Keratin1, Keratin10, KPP, KRT 1, Krt 10, KRT1, KRT10, KRT1A, KRTA, NEPPK
Host Species: Rabbit
Purification Method: Protein A or G purified
Research Discipline: Cytoskeleton Markers
Gene ID (Entrez): 3858.0
Target Species: Human, Mouse
Form: Purified
Antigen:
Cytokeratin 1/10
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1 ug/ml, Immunohistochemistry-Paraffin 0.1-0.2 ug/ml
Gene Accession No.:
P13645
Gene Symbols:
KRT10
Immunogen:
Recombinant human full-length Cytokeratin 10 protein (Uniprot: P13645)
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
Content And Storage:
Store at 4°C.
Isotype:
IgG
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
KRT10/1990R
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
67 kDa cytokeratin, CK 1, CK 10, CK1, CK10, Cytokeratin 10, Cytokeratin1, Cytokeratin10, EHK 1, EHK1, EPPK, Hair Alpha Protein, K1, k10, Keratin 1, Keratin 1 (epidermolytic hyperkeratosis), Keratin 10, Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris), Keratin type I cytoskeletal 10, Keratin Type II Cytoskeletal 1, Keratin1, Keratin10, KPP, KRT 1, Krt 10, KRT1, KRT10, KRT1A, KRTA, NEPPK
Host Species:
Rabbit
Purification Method:
Protein A or G purified
Research Discipline:
Cytoskeleton Markers
Gene ID (Entrez):
3858.0
Target Species:
Human, Mouse
Form:
Purified
Antigen: Elastin alpha
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P15502
Gene Symbols: ELN
Immunogen: Recombinant full-length human Elastin protein (Uniprot: P15502)
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: ELN/1981
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: elastin, FLJ38671, FLJ43523, SVAS, tropoelastin, WBS, WS
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Extracellular Matrix
Gene ID (Entrez): 2006.0
Target Species: Human
Form: Purified
Antigen:
Elastin alpha
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P15502
Gene Symbols:
ELN
Immunogen:
Recombinant full-length human Elastin protein (Uniprot: P15502)
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
ELN/1981
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
elastin, FLJ38671, FLJ43523, SVAS, tropoelastin, WBS, WS
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Extracellular Matrix
Gene ID (Entrez):
2006.0
Target Species:
Human
Form:
Purified