NBP47853B
Bcl-2 Antibody (BCL2/782 + BCL2/796), Biotin, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP47853B-Each-of-1 | In Stock | ₹ 56,298.48 |
NBP47853B - Each of 1
In Stock
Quantity
1
Base Price: ₹ 56,298.48
GST (18%): ₹ 10,133.726
Total Price: ₹ 66,432.206
Antigen
Bcl-2
Classification
Monoclonal
Conjugate
Biotin
Formulation
PBS with 0.05% Sodium Azide
Gene Symbols
BCL2
Immunogen
Recombinant full-length human bcl-2 protein (Uniprot: P10415)
Quantity
0.1 mL
Primary or Secondary
Primary
Test Specificity
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.
Content And Storage
Store at 4C in the dark.
Isotype
IgG1 κ
Applications
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone
BCL2/782 + BCL2/796
Dilution
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2
Host Species
Mouse
Purification Method
Protein A or G purified
Research Discipline
Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Phospho Specific, Tumor Suppressors
Gene ID (Entrez)
596
Target Species
Human
Form
Purified
Related Products
Description
- Bcl-2 Monoclonal specifically detects Bcl-2 in Human samples
- It is validated for Western Blot, Immunohistochemistry, Immunohistochemistry-Paraffin.
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Antigen: Bcl-2
Classification: Monoclonal
Conjugate: Biotin
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: BCL2
Immunogen: Recombinant full-length human bcl-2 protein (Uniprot: P10415)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: BCL2/782 + BCL2/796
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias: apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Phospho Specific, Tumor Suppressors
Gene ID (Entrez): 596
Target Species: Human
Form: Purified
Antigen:
Bcl-2
Classification:
Monoclonal
Conjugate:
Biotin
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
BCL2
Immunogen:
Recombinant full-length human bcl-2 protein (Uniprot: P10415)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
BCL2/782 + BCL2/796
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias:
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Apoptosis, Autophagy, Biologically Active Proteins, Cancer, Cellular Markers, Mitochondrial Mediated Pathway, Mitophagy, Oncogenes, Phospho Specific, Tumor Suppressors
Gene ID (Entrez):
596
Target Species:
Human
Form:
Purified
Antigen: Androgen R/NR3C4
Classification: Monoclonal
Conjugate: Biotin
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: AR
Immunogen: A synthetic peptide, aa 302-318 of human Androgen R/NR3C4 (Androgen R/NR3C4441); Recombinant human DHTR protein (DHTR/882) (Uniprot: P10275)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin. This monoclonal antibody is superb for staining of formalin/paraffin tissues.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Applications: Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: AR441 + DHTR/882
Dilution: Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias: AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Breast Cancer, Cancer, Cellular Markers, Phospho Specific
Gene ID (Entrez): 367
Target Species: Human, Mouse (Negative)
Form: Purified
Antigen:
Androgen R/NR3C4
Classification:
Monoclonal
Conjugate:
Biotin
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
AR
Immunogen:
A synthetic peptide, aa 302-318 of human Androgen R/NR3C4 (Androgen R/NR3C4441); Recombinant human DHTR protein (DHTR/882) (Uniprot: P10275)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of 110kDa, which is identified as androgen receptor (AR). It reacts with full length, and the newly described A form of the receptor. It does not cross react with estrogen, progesterone, or glucocorticoid receptors. The expression of AR is reportedly inversely correlated with histologic grade i.e. well differentiated prostate tumors show higher expression than the poorly differentiated tumors. In prostate cancer, AR has been proposed, as a marker of hormone-responsiveness and thus it may be useful in identifying patients likely to benefit from anti-androgen therapy. Anti-androgen receptor has been useful clinically in differentiating morpheaform basal cell carcinoma (mBCC) from desmoplastic trichoepithelioma (DTE) in the skin. This monoclonal antibody is superb for staining of formalin/paraffin tissues.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
AR441 + DHTR/882
Dilution:
Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias:
AIS, androgen receptor, DHTRTFM, Dihydrotestosterone receptorHYSP1, HUMARA, NR3C4KD, Nuclear receptor subfamily 3 group C member 4, SMAX1SBMA, spinal and bulbar muscular atrophy
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Breast Cancer, Cancer, Cellular Markers, Phospho Specific
Gene ID (Entrez):
367
Target Species:
Human, Mouse (Negative)
Form:
Purified
Antigen: WT1
Classification: Monoclonal
Conjugate: Biotin
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: WT1
Immunogen: Recombinant full length human WT1 protein (WT1/857); Recombinant fragment aa1-181 of human WT1 (6F-H2) (Uniprot: P19544)
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a 47-55kDa-tumor suppressor protein, identified as Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone: WT1/857 + 6F-H2
Dilution: Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias: AWT1, NPHS4GUD, WAGR, Wilms tumor 1, Wilms tumor protein, WIT-2, WT33
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Angiogenesis, Cancer, Cell Cycle and Replication, Cellular Markers, Chromatin Research, Tumor Suppressors
Gene ID (Entrez): 7490
Target Species: Human, Mouse, Rat
Form: Purified
Antigen:
WT1
Classification:
Monoclonal
Conjugate:
Biotin
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
WT1
Immunogen:
Recombinant full length human WT1 protein (WT1/857); Recombinant fragment aa1-181 of human WT1 (6F-H2) (Uniprot: P19544)
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a 47-55kDa-tumor suppressor protein, identified as Wilms tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunofluorescence
Clone:
WT1/857 + 6F-H2
Dilution:
Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias:
AWT1, NPHS4GUD, WAGR, Wilms tumor 1, Wilms tumor protein, WIT-2, WT33
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Angiogenesis, Cancer, Cell Cycle and Replication, Cellular Markers, Chromatin Research, Tumor Suppressors
Gene ID (Entrez):
7490
Target Species:
Human, Mouse, Rat
Form:
Purified
Antigen: Nucleolin
Classification: Monoclonal
Conjugate: Biotin
Formulation: PBS with 0.05% Sodium Azide
Gene Symbols: NCL
Immunogen: Lysate of SU-DHL-1 Nuclei (364-5); Recombinant human NCL protein (NCL/902) (Uniprot: P19338 )
Quantity: 0.1 mL
Primary or Secondary: Primary
Test Specificity: Recognizes a protein of ∼76kDa, which is identified as Nucleolin (NCL). It is the major nucleolar phosphoprotein of growing eukaryotic cells. NCL is located mainly in dense fibrillar regions of the nucleolus. It is found associated with intranucleolar chromatin and pre-ribosomal particles. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. This monoclonal antibody can be used to stain the nucleoli in cell or tissue preparations and can be used as a marker of the nucleoli in subcellular fractions. It produces a speckled pattern in the nuclei of cells of normal and malignant cells and may be used to stain the nucleoli of cells in fixed or frozen tissue sections. It can be used with paraformaldehyde fixed frozen tissue or cell preparations and formalin fixed, paraffin-embedded tissue sections.
Content And Storage: Store at 4C in the dark.
Isotype: IgG1 κ
Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: 364-5 + NCL/902
Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias: C23, FLJ45706, FLJ59041, nucleolin, Protein C23
Host Species: Mouse
Purification Method: Protein A or G purified
Research Discipline: Cell Cycle and Replication, Chromatin Research, Core ESC Like Genes, DNA Repair, DNA replication Transcription Translation and Splicing, Phospho Specific, Stem Cell Markers
Gene ID (Entrez): 4691
Target Species: Human, Bovine (Negative), Mouse (Negative), Rat (Negative)
Form: Purified
Antigen:
Nucleolin
Classification:
Monoclonal
Conjugate:
Biotin
Formulation:
PBS with 0.05% Sodium Azide
Gene Symbols:
NCL
Immunogen:
Lysate of SU-DHL-1 Nuclei (364-5); Recombinant human NCL protein (NCL/902) (Uniprot: P19338 )
Quantity:
0.1 mL
Primary or Secondary:
Primary
Test Specificity:
Recognizes a protein of ∼76kDa, which is identified as Nucleolin (NCL). It is the major nucleolar phosphoprotein of growing eukaryotic cells. NCL is located mainly in dense fibrillar regions of the nucleolus. It is found associated with intranucleolar chromatin and pre-ribosomal particles. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly. This monoclonal antibody can be used to stain the nucleoli in cell or tissue preparations and can be used as a marker of the nucleoli in subcellular fractions. It produces a speckled pattern in the nuclei of cells of normal and malignant cells and may be used to stain the nucleoli of cells in fixed or frozen tissue sections. It can be used with paraformaldehyde fixed frozen tissue or cell preparations and formalin fixed, paraffin-embedded tissue sections.
Content And Storage:
Store at 4C in the dark.
Isotype:
IgG1 κ
Applications:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
364-5 + NCL/902
Dilution:
Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin, Immunofluorescence
Gene Alias:
C23, FLJ45706, FLJ59041, nucleolin, Protein C23
Host Species:
Mouse
Purification Method:
Protein A or G purified
Research Discipline:
Cell Cycle and Replication, Chromatin Research, Core ESC Like Genes, DNA Repair, DNA replication Transcription Translation and Splicing, Phospho Specific, Stem Cell Markers
Gene ID (Entrez):
4691
Target Species:
Human, Bovine (Negative), Mouse (Negative), Rat (Negative)
Form:
Purified