NBP275770
Elastin Antibody (ELN/1981) - Azide and BSA Free, Novus Biologicals™
Manufacturer: Novus Biologicals
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP275770-Each-of-1 | In Stock | ₹ 55,485.66 |
NBP275770 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,485.66
GST (18%): ₹ 9,987.419
Total Price: ₹ 65,473.079
Antigen
Elastin alpha
Classification
Monoclonal
Concentration
0.2 mg/ml
Dilution
ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.
P15502
Gene Symbols
ELN
Immunogen
Recombinant full-length human Elastin protein (Uniprot: P15502)
Purification Method
Protein A or G purified
Research Discipline
Extracellular Matrix
Gene ID (Entrez)
2006.0
Target Species
Human
Form
Purified
Applications
ELISA, Immunohistochemistry (Paraffin)
Clone
ELN/1981
Conjugate
Unconjugated
Formulation
10 mM PBS with No Preservative
Gene Alias
elastin, FLJ38671, FLJ43523, SVAS, tropoelastin, WBS, WS
Host Species
Mouse
Molecular Weight of Antigen
70 kDa
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.
Content And Storage
Store at 4°C.
Isotype
IgG1 κ
Description
- Elastin Monoclonal specifically detects Elastin in Human samples
- It is validated for ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.
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Antigen: Elastin alpha
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P15502
Gene Symbols: ELN
Immunogen: Recombinant full-length human Elastin protein (Uniprot: P15502)
Purification Method: Protein A or G purified
Research Discipline: Extracellular Matrix
Gene ID (Entrez): 2006.0
Target Species: Human
Form: Purified
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: ELN/1981
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: elastin, FLJ38671, FLJ43523, SVAS, tropoelastin, WBS, WS
Host Species: Mouse
Molecular Weight of Antigen: 70 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Antigen:
Elastin alpha
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P15502
Gene Symbols:
ELN
Immunogen:
Recombinant full-length human Elastin protein (Uniprot: P15502)
Purification Method:
Protein A or G purified
Research Discipline:
Extracellular Matrix
Gene ID (Entrez):
2006.0
Target Species:
Human
Form:
Purified
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
ELN/1981
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
elastin, FLJ38671, FLJ43523, SVAS, tropoelastin, WBS, WS
Host Species:
Mouse
Molecular Weight of Antigen:
70 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Antigen: MyoD
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.: P15172, P15172
Gene Symbols: MYOD1
Immunogen: Recombinant human full-length MyoD protein (Uniprot: P15172 )
Purification Method: Protein A purified
Research Discipline: Cancer, Cell Cycle and Replication, Growth and Development, Phospho Specific
Gene ID (Entrez): 4654.0
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: MYOD1/2075R
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: bHLHc1BHLHC1, Class C basic helix-loop-helix protein 1, MYF3Myf-3, MYODmyoblast determination protein 1, myogenic differentiation 1, Myogenic factor 3myf-3, PUM
Host Species: Rabbit
Molecular Weight of Antigen: 45 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Recognizes a phospho-protein of 45kDa, identified as MyoD1. This monoclonal antibody does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas. Only nuclear staining should be considered as evidence of skeletal muscle differentiation.
Content And Storage: Store at 4°C.
Isotype: IgG
Antigen:
MyoD
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.:
P15172, P15172
Gene Symbols:
MYOD1
Immunogen:
Recombinant human full-length MyoD protein (Uniprot: P15172 )
Purification Method:
Protein A purified
Research Discipline:
Cancer, Cell Cycle and Replication, Growth and Development, Phospho Specific
Gene ID (Entrez):
4654.0
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
MYOD1/2075R
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
bHLHc1BHLHC1, Class C basic helix-loop-helix protein 1, MYF3Myf-3, MYODmyoblast determination protein 1, myogenic differentiation 1, Myogenic factor 3myf-3, PUM
Host Species:
Rabbit
Molecular Weight of Antigen:
45 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Recognizes a phospho-protein of 45kDa, identified as MyoD1. This monoclonal antibody does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas. Only nuclear staining should be considered as evidence of skeletal muscle differentiation.
Content And Storage:
Store at 4°C.
Isotype:
IgG
Antigen: Filaggrin
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.: P20930
Gene Symbols: FLG
Immunogen: Recombinant human Filaggrin protein fragment (around aa 998-1104) (exact sequence is proprietary) (Uniprot: P20930)
Purification Method: Protein A or G purified
Research Discipline: Cytoskeleton Markers
Gene ID (Entrez): 2312.0
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: FLG/1563
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage: Store at 4°C.
Isotype: IgG2b κ
Antigen:
Filaggrin
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.:
P20930
Gene Symbols:
FLG
Immunogen:
Recombinant human Filaggrin protein fragment (around aa 998-1104) (exact sequence is proprietary) (Uniprot: P20930)
Purification Method:
Protein A or G purified
Research Discipline:
Cytoskeleton Markers
Gene ID (Entrez):
2312.0
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
FLG/1563
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage:
Store at 4°C.
Isotype:
IgG2b κ
Antigen: UCH-L1/PGP9.5
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Western Blot 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P09936
Gene Symbols: UCHL1
Immunogen: Recombinant full-length human UCH-L1/PGP9.5 protein (Uniprot: P09936)
Purification Method: Protein A or G purified
Research Discipline: __
Gene ID (Entrez): 7345.0
Target Species: Human, Rat
Form: Purified
Applications: Western Blot, Immunohistochemistry (Paraffin)
Clone: rUCHL1/775
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This MAb reacts with a protein of 20-30 kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UCH-L1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Antigen:
UCH-L1/PGP9.5
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Western Blot 0.5-1 ug/ml, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P09936
Gene Symbols:
UCHL1
Immunogen:
Recombinant full-length human UCH-L1/PGP9.5 protein (Uniprot: P09936)
Purification Method:
Protein A or G purified
Research Discipline:
__
Gene ID (Entrez):
7345.0
Target Species:
Human, Rat
Form:
Purified
Applications:
Western Blot, Immunohistochemistry (Paraffin)
Clone:
rUCHL1/775
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
EC 3.4.19.12, EC 6.-, Neuron cytoplasmic protein 9.5, PARK5, PGP 9.5, PGP9.5, PGP9.5Uch-L1, PGP95, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase), ubiquitin carboxyl-terminal hydrolase isozyme L1, ubiquitin C-terminal hydrolase, Ubiquitin thioesterase L1, UCHL1, UCH-L1
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This MAb reacts with a protein of 20-30 kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UCH-L1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ