NBP275768
Cytokeratin 10 Antibody (KRT10/1990R) - Azide and BSA Free, Novus Biologicals™
Manufacturer: Novus Biologicals
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | NBP275768-Each-of-1 | In Stock | ₹ 55,271.76 |
NBP275768 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 55,271.76
GST (18%): ₹ 9,948.917
Total Price: ₹ 65,220.677
Antigen
Cytokeratin 1/10
Classification
Monoclonal
Concentration
0.2 mg/ml
Dilution
Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1 ug/ml, Immunohistochemistry-Paraffin 0.1-0.2 ug/ml
Gene Accession No.
P13645
Gene Symbols
KRT10
Immunogen
Recombinant human full-length Cytokeratin 10 protein (Uniprot: P13645)
Purification Method
Protein A or G purified
Research Discipline
Cytoskeleton Markers
Gene ID (Entrez)
3858.0
Target Species
Human, Mouse
Form
Purified
Applications
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone
KRT10/1990R
Conjugate
Unconjugated
Formulation
10 mM PBS with No Preservative
Gene Alias
67 kDa cytokeratin, CK 1, CK 10, CK1, CK10, Cytokeratin 10, Cytokeratin1, Cytokeratin10, EHK 1, EHK1, EPPK, Hair Alpha Protein, K1, k10, Keratin 1, Keratin 1 (epidermolytic hyperkeratosis), Keratin 10, Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris), Keratin type I cytoskeletal 10, Keratin Type II Cytoskeletal 1, Keratin1, Keratin10, KPP, KRT 1, Krt 10, KRT1, KRT10, KRT1A, KRTA, NEPPK
Host Species
Rabbit
Molecular Weight of Antigen
56.5 kDa
Quantity
100 μg
Primary or Secondary
Primary
Test Specificity
This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
Content And Storage
Store at 4°C.
Isotype
IgG
Description
- Cytokeratin 10 Monoclonal specifically detects Cytokeratin 10 in Human, Mouse samples
- It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin.
Compare Similar Items
Show Difference
Antigen: Cytokeratin 1/10
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1 ug/ml, Immunohistochemistry-Paraffin 0.1-0.2 ug/ml
Gene Accession No.: P13645
Gene Symbols: KRT10
Immunogen: Recombinant human full-length Cytokeratin 10 protein (Uniprot: P13645)
Purification Method: Protein A or G purified
Research Discipline: Cytoskeleton Markers
Gene ID (Entrez): 3858.0
Target Species: Human, Mouse
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone: KRT10/1990R
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: 67 kDa cytokeratin, CK 1, CK 10, CK1, CK10, Cytokeratin 10, Cytokeratin1, Cytokeratin10, EHK 1, EHK1, EPPK, Hair Alpha Protein, K1, k10, Keratin 1, Keratin 1 (epidermolytic hyperkeratosis), Keratin 10, Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris), Keratin type I cytoskeletal 10, Keratin Type II Cytoskeletal 1, Keratin1, Keratin10, KPP, KRT 1, Krt 10, KRT1, KRT10, KRT1A, KRTA, NEPPK
Host Species: Rabbit
Molecular Weight of Antigen: 56.5 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
Content And Storage: Store at 4°C.
Isotype: IgG
Antigen:
Cytokeratin 1/10
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Flow Cytometry 0.5-1 ug/million cells, Immunocytochemistry/Immunofluorescence 0.5-1 ug/ml, Immunohistochemistry-Paraffin 0.1-0.2 ug/ml
Gene Accession No.:
P13645
Gene Symbols:
KRT10
Immunogen:
Recombinant human full-length Cytokeratin 10 protein (Uniprot: P13645)
Purification Method:
Protein A or G purified
Research Discipline:
Cytoskeleton Markers
Gene ID (Entrez):
3858.0
Target Species:
Human, Mouse
Form:
Purified
Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
Clone:
KRT10/1990R
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
67 kDa cytokeratin, CK 1, CK 10, CK1, CK10, Cytokeratin 10, Cytokeratin1, Cytokeratin10, EHK 1, EHK1, EPPK, Hair Alpha Protein, K1, k10, Keratin 1, Keratin 1 (epidermolytic hyperkeratosis), Keratin 10, Keratin 10 (epidermolytic hyperkeratosis; keratosis palmaris et plantaris), Keratin type I cytoskeletal 10, Keratin Type II Cytoskeletal 1, Keratin1, Keratin10, KPP, KRT 1, Krt 10, KRT1, KRT10, KRT1A, KRTA, NEPPK
Host Species:
Rabbit
Molecular Weight of Antigen:
56.5 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
This MAb recognizes a protein of 56.5 kDa, identified as cytokeratin 10 (CK10). CK10 is expressed in all suprabasal layers of the epidermis. In the epidermis, expression of CK10 strictly parallels the extent of differentiation; it is absent in the basal layer, appears in the first suprabasal layers and increases in concentration towards the granular layer. However, CK10 is rarely detected in early stages of vulvar squamous carcinomas (tumors less than 2 cm, clinical stage I) regardless of the tumor grade. In larger and more advanced tumors (greater than 2 cm, clinical stages II and III), CK10 is detected very frequently. Expression of CK10 is related to maturation of malignant keratinocytes, being preferentially detected in more-differentiated parts.
Content And Storage:
Store at 4°C.
Isotype:
IgG
Antigen: Elastin alpha
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.: P15502
Gene Symbols: ELN
Immunogen: Recombinant full-length human Elastin protein (Uniprot: P15502)
Purification Method: Protein A or G purified
Research Discipline: Extracellular Matrix
Gene ID (Entrez): 2006.0
Target Species: Human
Form: Purified
Applications: ELISA, Immunohistochemistry (Paraffin)
Clone: ELN/1981
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: elastin, FLJ38671, FLJ43523, SVAS, tropoelastin, WBS, WS
Host Species: Mouse
Molecular Weight of Antigen: 70 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.
Content And Storage: Store at 4°C.
Isotype: IgG1 κ
Antigen:
Elastin alpha
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
ELISA, Immunohistochemistry-Paraffin 1-2 ug/ml
Gene Accession No.:
P15502
Gene Symbols:
ELN
Immunogen:
Recombinant full-length human Elastin protein (Uniprot: P15502)
Purification Method:
Protein A or G purified
Research Discipline:
Extracellular Matrix
Gene ID (Entrez):
2006.0
Target Species:
Human
Form:
Purified
Applications:
ELISA, Immunohistochemistry (Paraffin)
Clone:
ELN/1981
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
elastin, FLJ38671, FLJ43523, SVAS, tropoelastin, WBS, WS
Host Species:
Mouse
Molecular Weight of Antigen:
70 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension.
Content And Storage:
Store at 4°C.
Isotype:
IgG1 κ
Antigen: MyoD
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.: P15172, P15172
Gene Symbols: MYOD1
Immunogen: Recombinant human full-length MyoD protein (Uniprot: P15172 )
Purification Method: Protein A purified
Research Discipline: Cancer, Cell Cycle and Replication, Growth and Development, Phospho Specific
Gene ID (Entrez): 4654.0
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: MYOD1/2075R
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: bHLHc1BHLHC1, Class C basic helix-loop-helix protein 1, MYF3Myf-3, MYODmyoblast determination protein 1, myogenic differentiation 1, Myogenic factor 3myf-3, PUM
Host Species: Rabbit
Molecular Weight of Antigen: 45 kDa
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Recognizes a phospho-protein of 45kDa, identified as MyoD1. This monoclonal antibody does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas. Only nuclear staining should be considered as evidence of skeletal muscle differentiation.
Content And Storage: Store at 4°C.
Isotype: IgG
Antigen:
MyoD
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.:
P15172, P15172
Gene Symbols:
MYOD1
Immunogen:
Recombinant human full-length MyoD protein (Uniprot: P15172 )
Purification Method:
Protein A purified
Research Discipline:
Cancer, Cell Cycle and Replication, Growth and Development, Phospho Specific
Gene ID (Entrez):
4654.0
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
MYOD1/2075R
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
bHLHc1BHLHC1, Class C basic helix-loop-helix protein 1, MYF3Myf-3, MYODmyoblast determination protein 1, myogenic differentiation 1, Myogenic factor 3myf-3, PUM
Host Species:
Rabbit
Molecular Weight of Antigen:
45 kDa
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Recognizes a phospho-protein of 45kDa, identified as MyoD1. This monoclonal antibody does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas. Only nuclear staining should be considered as evidence of skeletal muscle differentiation.
Content And Storage:
Store at 4°C.
Isotype:
IgG
Antigen: Filaggrin
Classification: Monoclonal
Concentration: 0.2 mg/ml
Dilution: Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.: P20930
Gene Symbols: FLG
Immunogen: Recombinant human Filaggrin protein fragment (around aa 998-1104) (exact sequence is proprietary) (Uniprot: P20930)
Purification Method: Protein A or G purified
Research Discipline: Cytoskeleton Markers
Gene ID (Entrez): 2312.0
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: FLG/1563
Conjugate: Unconjugated
Formulation: 10 mM PBS with No Preservative
Gene Alias: ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species: Mouse
Molecular Weight of Antigen: __
Quantity: 100 μg
Primary or Secondary: Primary
Test Specificity: Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage: Store at 4°C.
Isotype: IgG2b κ
Antigen:
Filaggrin
Classification:
Monoclonal
Concentration:
0.2 mg/ml
Dilution:
Immunohistochemistry-Paraffin 0.5-1 ug/ml
Gene Accession No.:
P20930
Gene Symbols:
FLG
Immunogen:
Recombinant human Filaggrin protein fragment (around aa 998-1104) (exact sequence is proprietary) (Uniprot: P20930)
Purification Method:
Protein A or G purified
Research Discipline:
Cytoskeleton Markers
Gene ID (Entrez):
2312.0
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
FLG/1563
Conjugate:
Unconjugated
Formulation:
10 mM PBS with No Preservative
Gene Alias:
ATOD2, epidermal filaggrin, filaggrin, Profilaggrin
Host Species:
Mouse
Molecular Weight of Antigen:
__
Quantity:
100 μg
Primary or Secondary:
Primary
Test Specificity:
Filaggrin is an intermediate filament-associated protein that aggregates keratin intermediate filaments in mammalian epidermis. It is initially synthesized as a polyprotein precursor, profilaggrin (consisting of multiple filaggrin units of 324 aa each), which is localized in keratohyalin granules, and is subsequently proteolytically processed into individual functional filaggrin molecules. Active filaggrin is present at a level of the epidermis where keratinocytes are in transition between the live nucleated granular layer and the anucleate cornified layer, suggesting that filaggrin aids in the terminal differentiation process by facilitating apoptotic machinery.
Content And Storage:
Store at 4°C.
Isotype:
IgG2b κ