NBP275750

TCL1A Antibody (TCL1/2078) - Azide and BSA Free, Novus Biologicals™

Manufacturer: Novus Biologicals

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Pack Size SKU Availability Price
Each of 1 NBP275750-Each-of-1 In Stock ₹ 55,271.76

NBP275750 - Each of 1

₹ 55,271.76

In Stock

Quantity

1

Base Price: ₹ 55,271.76

GST (18%): ₹ 9,948.917

Total Price: ₹ 65,220.677

Antigen

TCL1A

Classification

Monoclonal

Concentration

0.2 mg/ml

Dilution

Immunohistochemistry-Paraffin 1-2 ug/ml

Gene Accession No.

P56279, P56279

Gene Symbols

TCL1A

Immunogen

Recombinant human TCL1A protein fragment (around aa 2-109) (exact sequence is proprietary) (Uniprot: P56279)

Purification Method

Protein A or G purified

Primary or Secondary

Primary

Test Specificity

T-cell leukemia/Lymphoma Protein 1A (TCL1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.

Content And Storage

Store at 4°C.

Isotype

IgG1 κ

Applications

Immunohistochemistry (Paraffin)

Clone

TCL1/2078

Conjugate

Unconjugated

Formulation

10 mM PBS with No Preservative

Gene Alias

Oncogene TCL1, Oncogene TCL-1, Protein p14 TCL1, T-cell leukemia/lymphoma 1A, T-cell lymphoma-1, T-cell lymphoma-1A, TCL1T-cell leukemia/lymphoma protein 1A

Host Species

Mouse

Molecular Weight of Antigen

14 kDa

Quantity

100 μg

Gene ID (Entrez)

8115.0

Target Species

Human

Form

Purified

Description

  • TCL1A Monoclonal specifically detects TCL1A in Human samples
  • It is validated for Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array.

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Novus Biologicals

NBP275750

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Antigen:
TCL1A

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Immunohistochemistry-Paraffin 1-2 ug/ml

Gene Accession No.:
P56279, P56279

Gene Symbols:
TCL1A

Immunogen:
Recombinant human TCL1A protein fragment (around aa 2-109) (exact sequence is proprietary) (Uniprot: P56279)

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
T-cell leukemia/Lymphoma Protein 1A (TCL1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.

Content And Storage:
Store at 4°C.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
TCL1/2078

Conjugate:
Unconjugated

Formulation:
10 mM PBS with No Preservative

Gene Alias:
Oncogene TCL1, Oncogene TCL-1, Protein p14 TCL1, T-cell leukemia/lymphoma 1A, T-cell lymphoma-1, T-cell lymphoma-1A, TCL1T-cell leukemia/lymphoma protein 1A

Host Species:
Mouse

Molecular Weight of Antigen:
14 kDa

Quantity:
100 μg

Gene ID (Entrez):
8115.0

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP275759

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Antigen:
CDX2

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Western Blot 0.5-1.0 ug/ml, Immunoprecipitation 2-4 ug/mg protein, Immunohistochemistry-Paraffin 0.5-1 ug/ml

Gene Accession No.:
Q99626, Q99626

Gene Symbols:
CDX2

Immunogen:
Recombinant human full-length CDX2 protein (Uniprot: Q99626)

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
The specificity of this monoclonal antibody to its intended target was validated by HuProtTMArray, containing more than 19,000, full-length human proteins. The intestine-specific transcription factors CDX1 and CDX2 are important for directing intestinal development, differentiation, proliferation and maintenance of the intestinal phenotype. CDX2 protein expression has been seen in GI carcinomas. Anti-CDX2 has been useful to establish GI origin of metastatic adenocarcinomas and carcinoids and is especially useful to distinguish metastatic colorectal adenocarcinoma from lung adenocarcinoma. However, mucinous carcinomas of the ovary also express CDX2 protein. It limits the usefulness of this marker in the distinction of metastatic colorectal adenocarcinoma from mucinous carcinoma of the ovary.

Content And Storage:
Store at 4°C.

Isotype:
IgG1 κ

Applications:
Western Blot, Immunoprecipitation, Immunohistochemistry (Paraffin)

Clone:
PCRP-CDX2-1A3

Conjugate:
Unconjugated

Formulation:
10 mM PBS with No Preservative

Gene Alias:
caudal type homeo box transcription factor 2, caudal type homeobox 2, Caudal-type homeobox protein 2, CDX-3, CDX3caudal type homeobox transcription factor 2, homeobox protein CDX-2

Host Species:
Mouse

Molecular Weight of Antigen:
40 kDa

Quantity:
100 μg

Gene ID (Entrez):
1045.0

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP275760

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Antigen:
AIF-1/Iba1

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Immunohistochemistry-Paraffin 1-2 ug/ml

Gene Accession No.:
P55008

Gene Symbols:
AIF1

Immunogen:
Purified recombinant human AIF-1/Iba1 protein (around aa 1-146) (exact sequence is proprietary) (Uniprot: P55008)

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
AIF1 is a cytoplasmic, calcium-binding protein that is thought to play a role in macrophage activation and function. AIF1, containing two EF domains, is induced by cytokines and Interferons. In an unstimulated state, AIF1 colocalizes with actin, and upon stimulation, translocates to lamellipodia. It is also a marker of human microglia and is expressed by macrophages in injured skeletal muscle. The gene encoding AIF1 resides in the tumor necrosis factor (TNF) cluster of genes, located in the region represented by the human major histocompatibility complex (MHC).

Content And Storage:
Store at 4°C.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin)

Clone:
rAIF1/1909

Conjugate:
Unconjugated

Formulation:
10 mM PBS with No Preservative

Gene Alias:
AIF-1, allograft inflammatory factor 1, G1, IBA1, IbaI, interferon gamma responsive transcript, Ionized calcium-binding adapter molecule 1, IRT1, IRT-1, Protein G1

Host Species:
Mouse

Molecular Weight of Antigen:
16.7 kDa

Quantity:
100 μg

Gene ID (Entrez):
199.0

Target Species:
Human

Form:
Purified

Img

Novus Biologicals

NBP275764

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Antigen:
Bcl-2

Classification:
Monoclonal

Concentration:
0.2 mg/ml

Dilution:
Western Blot 0.5 - 1 μg/mL, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1 - 2 μg/mL, Immunohistochemistry-Paraffin 0.5 - 1 μg/mL, Protein Array

Gene Accession No.:
P10415, P10415

Gene Symbols:
BCL2

Immunogen:
Recombinant full-length human bcl-2 protein (Uniprot: P10415)

Purification Method:
Protein A or G purified

Primary or Secondary:
Primary

Test Specificity:
This antibody recognizes a protein of 25-26kDa, identified as the Bcl-2 lpha oncoprotein. It shows no cross-reaction with Bcl-x or Bax protein. Expression of Bcl-2 lpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2 lpha protein, whereas the normal or hyperplastic germinal centers are negative. Consequently, this antibody is valuable when distinguishing between reactive and neoplastic follicular proliferation in lymph node biopsies. It may also be used in distinguishing between those follicular lymphomas that express Bcl-2 protein and the small number in which the neoplastic cells are Bcl-2 negative.

Content And Storage:
Store at 4°C.

Isotype:
IgG

Applications:
Western Blot, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Peptide Array

Clone:
BCL2/2210R

Conjugate:
Unconjugated

Formulation:
10 mM PBS with No Preservative

Gene Alias:
apoptosis regulator Bcl-2, B-cell CLL/lymphoma 2, Bcl-2

Host Species:
Rabbit

Molecular Weight of Antigen:
__

Quantity:
100 μg

Gene ID (Entrez):
596.0

Target Species:
Human

Form:
Purified